Prognostic value of usual gait speed in well-functioning older people -- results from the health, aging and body composition study.

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Title: Prognostic value of usual gait speed in well-functioning older people -- results from the health, aging and body composition study.
Authors: Cesari M (AUTHOR), Kritchevsky SB (AUTHOR), Penninx BW (AUTHOR), Nicklas BJ (AUTHOR), Simonsick EM (AUTHOR), Newman AB (AUTHOR), Tylavsky FA (AUTHOR), Brach JS (AUTHOR), Satterfield S (AUTHOR), Bauer DC (AUTHOR), Visser M (AUTHOR), Rubin SM (AUTHOR), Harris TB (AUTHOR), Pahor M (AUTHOR)
Source: Journal of the American Geriatrics Society. Oct2005, Vol. 53 Issue 10, p1675-1680. 6p.
Abstract: Objectives: To define clinically relevant cutpoints for usual gait speed and to investigate their predictive value for health-related events in older persons. Design: Prospective cohort study. Setting: Health, Aging and Body Composition Study. Participants: Three thousand forty-seven well-functioning older persons (mean age 74.2). Measurements: Usual gait speed on a 6-m course was assessed at baseline. Participants were randomly divided into two groups to identify (Sample A; n=2,031) and then validate (Sample B; n=1,016) usual gait-speed cutpoints. Rates of persistent lower extremity limitation events (mean follow-up 4.9 years) were calculated according to gait speed in Sample A. A cutpoint (defining high- (<1 m/s) and low risk (>/=1 m/s) groups) was identified based on persistent lower extremity limitation events. The predictive value of the identified cutpoints for major health-related events (persistent severe lower extremity limitation, death, and hospitalization) was evaluated in Sample B using Cox regression analyses. Results: A graded response was seen between risk groups and health-related outcomes. Participants in the high-risk group had a higher risk of persistent lower extremity limitation (rate ratio (RR)=2.20, 95% confidence interval (CI)=1.76-2.74), persistent severe lower extremity limitation (RR=2.29, 95% CI=1.63-3.20), death (RR=1.64, 95% CI=1.14-2.37), and hospitalization (RR=1.48, 95% CI=1.02-2.13) than those in the low-risk group. Conclusion: Usual gait speed of less than 1 m/s identifies persons at high risk of health-related outcomes in well-functioning older people. Provision of a clinically meaningful cutpoint for usual gait speed may facilitate its use in clinical and research settings. [ABSTRACT FROM AUTHOR]
Copyright of Journal of the American Geriatrics Society is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Prognostic value of usual gait speed in well-functioning older people -- results from the health, aging and body composition study.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Cesari+M%22&quot;&gt;Cesari M&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kritchevsky+SB%22&quot;&gt;Kritchevsky SB&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Penninx+BW%22&quot;&gt;Penninx BW&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Nicklas+BJ%22&quot;&gt;Nicklas BJ&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Simonsick+EM%22&quot;&gt;Simonsick EM&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Newman+AB%22&quot;&gt;Newman AB&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tylavsky+FA%22&quot;&gt;Tylavsky FA&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Brach+JS%22&quot;&gt;Brach JS&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Satterfield+S%22&quot;&gt;Satterfield S&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bauer+DC%22&quot;&gt;Bauer DC&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Visser+M%22&quot;&gt;Visser M&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rubin+SM%22&quot;&gt;Rubin SM&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Harris+TB%22&quot;&gt;Harris TB&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pahor+M%22&quot;&gt;Pahor M&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Journal+of+the+American+Geriatrics+Society%22&quot;&gt;Journal of the American Geriatrics Society&lt;/searchLink&gt;. Oct2005, Vol. 53 Issue 10, p1675-1680. 6p.
– Name: Abstract
  Label: Abstract
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  Data: Objectives: To define clinically relevant cutpoints for usual gait speed and to investigate their predictive value for health-related events in older persons. Design: Prospective cohort study. Setting: Health, Aging and Body Composition Study. Participants: Three thousand forty-seven well-functioning older persons (mean age 74.2). Measurements: Usual gait speed on a 6-m course was assessed at baseline. Participants were randomly divided into two groups to identify (Sample A; n=2,031) and then validate (Sample B; n=1,016) usual gait-speed cutpoints. Rates of persistent lower extremity limitation events (mean follow-up 4.9 years) were calculated according to gait speed in Sample A. A cutpoint (defining high- (&lt;1 m/s) and low risk (&gt;/=1 m/s) groups) was identified based on persistent lower extremity limitation events. The predictive value of the identified cutpoints for major health-related events (persistent severe lower extremity limitation, death, and hospitalization) was evaluated in Sample B using Cox regression analyses. Results: A graded response was seen between risk groups and health-related outcomes. Participants in the high-risk group had a higher risk of persistent lower extremity limitation (rate ratio (RR)=2.20, 95% confidence interval (CI)=1.76-2.74), persistent severe lower extremity limitation (RR=2.29, 95% CI=1.63-3.20), death (RR=1.64, 95% CI=1.14-2.37), and hospitalization (RR=1.48, 95% CI=1.02-2.13) than those in the low-risk group. Conclusion: Usual gait speed of less than 1 m/s identifies persons at high risk of health-related outcomes in well-functioning older people. Provision of a clinically meaningful cutpoint for usual gait speed may facilitate its use in clinical and research settings. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Journal of the American Geriatrics Society is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1111/j.1532-5415.2005.53501.x
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