Acute vitamin D intoxication in a child.
Saved in:
| Title: | Acute vitamin D intoxication in a child. |
|---|---|
| Authors: | Barrueto F Jr. (AUTHOR), Wang-Flores HH (AUTHOR), Howland MA (AUTHOR), Hoffman RS (AUTHOR), Nelson LS (AUTHOR) |
| Source: | Pediatrics. Sep2005, Vol. 116 Issue 3, pe453-6. 1p. |
| Abstract: | We present the unique case of a previously healthy, 2-year-old boy with resistant hypercalcemia and hypertension resulting from an unintentional overdose with an imported vitamin D supplement. The patient presented initially to the emergency department with colic and constipation and was discharged after a benign physical examination. The symptoms persisted and, on the second visit, the patient was found to have a serum calcium level of 14.4 mg/dL. Despite therapy with intravenously administered 5% dextrose solution at one-half normal strength, furosemide, calcitonin, and hydrocortisone, the calcium concentration increased to 15.0 mg/dL on the second hospital day and did not decrease until the fourth hospital day, when it fell to 13.9 mg/dL. The vitamin D concentration peaked at 470 ng/mL on hospital day 3. With additional questioning, the mother revealed that she had been giving her son a daily dose of 1 ampule of Raquiferol, an imported vitamin D supplement, instead of the recommended 2 drops per day. Each ampule contained 600000 IU of vitamin D; therefore, the boy received a total of 2400000 IU over 4 days. The patient's hypercalcemia persisted for 14 days and was complicated by persistent hypertension. No renal, cardiac, or neurologic complications were noted. At discharge, the vitamin D concentration was still elevated at 389 ng/mL and the total calcium level had decreased to 11 mg/dL. The boy made a complete clinical recovery. This case highlights the need for caution when using imported and/or unregulated medicines, as well as the dangers of parental dosing errors. [ABSTRACT FROM AUTHOR] |
| Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 106531602 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Acute vitamin D intoxication in a child. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Barrueto+F+Jr%2E%22">Barrueto F Jr.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang-Flores+HH%22">Wang-Flores HH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Howland+MA%22">Howland MA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hoffman+RS%22">Hoffman RS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nelson+LS%22">Nelson LS</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Sep2005, Vol. 116 Issue 3, pe453-6. 1p. – Name: Abstract Label: Abstract Group: Ab Data: We present the unique case of a previously healthy, 2-year-old boy with resistant hypercalcemia and hypertension resulting from an unintentional overdose with an imported vitamin D supplement. The patient presented initially to the emergency department with colic and constipation and was discharged after a benign physical examination. The symptoms persisted and, on the second visit, the patient was found to have a serum calcium level of 14.4 mg/dL. Despite therapy with intravenously administered 5% dextrose solution at one-half normal strength, furosemide, calcitonin, and hydrocortisone, the calcium concentration increased to 15.0 mg/dL on the second hospital day and did not decrease until the fourth hospital day, when it fell to 13.9 mg/dL. The vitamin D concentration peaked at 470 ng/mL on hospital day 3. With additional questioning, the mother revealed that she had been giving her son a daily dose of 1 ampule of Raquiferol, an imported vitamin D supplement, instead of the recommended 2 drops per day. Each ampule contained 600000 IU of vitamin D; therefore, the boy received a total of 2400000 IU over 4 days. The patient's hypercalcemia persisted for 14 days and was complicated by persistent hypertension. No renal, cardiac, or neurologic complications were noted. At discharge, the vitamin D concentration was still elevated at 389 ng/mL and the total calcium level had decreased to 11 mg/dL. The boy made a complete clinical recovery. This case highlights the need for caution when using imported and/or unregulated medicines, as well as the dangers of parental dosing errors. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=106531602 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1542/peds.2004-2580 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: e453 Titles: – TitleFull: Acute vitamin D intoxication in a child. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Barrueto F Jr. – PersonEntity: Name: NameFull: Wang-Flores HH – PersonEntity: Name: NameFull: Howland MA – PersonEntity: Name: NameFull: Hoffman RS – PersonEntity: Name: NameFull: Nelson LS IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2005 Type: published Y: 2005 Identifiers: – Type: issn-print Value: 00314005 Numbering: – Type: volume Value: 116 – Type: issue Value: 3 Titles: – TitleFull: Pediatrics Type: main |
| ResultId | 1 |
