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Fractures in patients with anorexia nervosa, bulimia nervosa, and other eating disorders -- a nationwide register study.

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Title: Fractures in patients with anorexia nervosa, bulimia nervosa, and other eating disorders -- a nationwide register study.
Authors: Vestergaard P (AUTHOR), Emborg C (AUTHOR), Støving RK (AUTHOR), Hagen C (AUTHOR), Mosekilde L (AUTHOR), Brixen K (AUTHOR)
Source: International Journal of Eating Disorders. Nov2002, Vol. 32 Issue 3, p301-308. 8p.
Abstract: OBJECTIVE: To study fracture risk in patients with anorexia nervosa (AN), bulimia nervosa (BN), or eating disorders not otherwise specified (EDNOS). METHOD: Cohort study including all Danes diagnosed with AN (n = 2,149), BN (n = 1,294), or EDNOS (n = 942) between 1977 and 1998. Each patient was compared with three randomly drawn age- and gender-matched control subjects. RESULTS: Fracture risk was increased in AN after diagnosis compared to controls (incidence rate ratio: 1.98, 95% CI: 1.60-2.44), but not before. The increased fracture risk persisted more than 10 years after diagnosis. A significant increase in fracture risk was found before diagnosis in BN (1.31, 95% CI: 1.04-1.64), with a trend towards an increase after diagnosis (1.44, 95% CI: 0.93-2.22). EDNOS patients had a significant increase in fracture risk before (1.39, 95% CI: 1.06-1.81) and after diagnosis (1.77, 95% CI: 1.25-2.51). DISCUSSION: The increased fracture risk many years after diagnosis indicates permanent skeletal damage. Copyright 2002 by Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Fractures in patients with anorexia nervosa, bulimia nervosa, and other eating disorders -- a nationwide register study.
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  Data: <searchLink fieldCode="AR" term="%22Vestergaard+P%22">Vestergaard P</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Emborg+C%22">Emborg C</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Støving+RK%22">Støving RK</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hagen+C%22">Hagen C</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mosekilde+L%22">Mosekilde L</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Brixen+K%22">Brixen K</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Eating+Disorders%22">International Journal of Eating Disorders</searchLink>. Nov2002, Vol. 32 Issue 3, p301-308. 8p.
– Name: Abstract
  Label: Abstract
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  Data: OBJECTIVE: To study fracture risk in patients with anorexia nervosa (AN), bulimia nervosa (BN), or eating disorders not otherwise specified (EDNOS). METHOD: Cohort study including all Danes diagnosed with AN (n = 2,149), BN (n = 1,294), or EDNOS (n = 942) between 1977 and 1998. Each patient was compared with three randomly drawn age- and gender-matched control subjects. RESULTS: Fracture risk was increased in AN after diagnosis compared to controls (incidence rate ratio: 1.98, 95% CI: 1.60-2.44), but not before. The increased fracture risk persisted more than 10 years after diagnosis. A significant increase in fracture risk was found before diagnosis in BN (1.31, 95% CI: 1.04-1.64), with a trend towards an increase after diagnosis (1.44, 95% CI: 0.93-2.22). EDNOS patients had a significant increase in fracture risk before (1.39, 95% CI: 1.06-1.81) and after diagnosis (1.77, 95% CI: 1.25-2.51). DISCUSSION: The increased fracture risk many years after diagnosis indicates permanent skeletal damage. Copyright 2002 by Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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