Effect of sunlight and season on serotonin turnover in the brain.

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Title: Effect of sunlight and season on serotonin turnover in the brain.
Authors: Lambert GW (AUTHOR), Reid C (AUTHOR), Kaye DM (AUTHOR), Jennings GL (AUTHOR), Esler MD (AUTHOR), Lambert, G W (AUTHOR), Reid, C (AUTHOR), Kaye, D M (AUTHOR), Jennings, G L (AUTHOR), Esler, M D (AUTHOR)
Source: Lancet. 12/7/2002, Vol. 360 Issue 9348, p1840-1842. 3p.
Abstract: Alterations in monoaminergic neurotransmission in the brain are thought to underlie seasonal variations in mood, behaviour, and affective disorders. We took blood samples from internal jugular veins in 101 healthy men, to assess the relation between concentration of serotonin metabolite in these samples and weather conditions and season. We showed that turnover of serotonin by the brain was lowest in winter (p=0.013). Moreover, the rate of production of serotonin by the brain was directly related to the prevailing duration of bright sunlight (r=0.294, p=0.010), and rose rapidly with increased luminosity. Our findings are further evidence for the notion that changes in release of serotonin by the brain underlie mood seasonality and seasonal affective disorder. [ABSTRACT FROM AUTHOR]
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  Data: Effect of sunlight and season on serotonin turnover in the brain.
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 12/7/2002, Vol. 360 Issue 9348, p1840-1842. 3p.
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Alterations in monoaminergic neurotransmission in the brain are thought to underlie seasonal variations in mood, behaviour, and affective disorders. We took blood samples from internal jugular veins in 101 healthy men, to assess the relation between concentration of serotonin metabolite in these samples and weather conditions and season. We showed that turnover of serotonin by the brain was lowest in winter (p=0.013). Moreover, the rate of production of serotonin by the brain was directly related to the prevailing duration of bright sunlight (r=0.294, p=0.010), and rose rapidly with increased luminosity. Our findings are further evidence for the notion that changes in release of serotonin by the brain underlie mood seasonality and seasonal affective disorder. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/s0140-6736(02)11737-5
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              Text: 12/7/2002
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