Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study.
Saved in:
| Title: | Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. |
|---|---|
| Authors: | Bingham SA (AUTHOR), Day NE (AUTHOR), Luben R (AUTHOR), Ferrari P (AUTHOR), Slimani N (AUTHOR), Norat T (AUTHOR), Clavel-Chapelon F (AUTHOR), Kesse E (AUTHOR), Nieters A (AUTHOR), Boeing H (AUTHOR), Tjønneland A (AUTHOR), Overvad K (AUTHOR), Martinez C (AUTHOR), Dorronsoro M (AUTHOR), Gonzalez CA (AUTHOR), Key TJ (AUTHOR), Trichopoulou A (AUTHOR), Naska A (AUTHOR), Vineis P (AUTHOR), Tumino R (AUTHOR) |
| Source: | Lancet. 5/3/2003, Vol. 361 Issue 9368, p1496-1501. 6p. |
| Abstract: | |
| Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
|
Full text is not displayed to guests.
Login for full access.
|
|
| FullText | Links: – Type: pdflink Text: Availability: 1 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 106874742 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Bingham+SA%22">Bingham SA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Day+NE%22">Day NE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Luben+R%22">Luben R</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ferrari+P%22">Ferrari P</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Slimani+N%22">Slimani N</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Norat+T%22">Norat T</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Clavel-Chapelon+F%22">Clavel-Chapelon F</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kesse+E%22">Kesse E</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nieters+A%22">Nieters A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Boeing+H%22">Boeing H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tjønneland+A%22">Tjønneland A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Overvad+K%22">Overvad K</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Martinez+C%22">Martinez C</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dorronsoro+M%22">Dorronsoro M</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gonzalez+CA%22">Gonzalez CA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Key+TJ%22">Key TJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Trichopoulou+A%22">Trichopoulou A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Naska+A%22">Naska A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vineis+P%22">Vineis P</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tumino+R%22">Tumino R</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 5/3/2003, Vol. 361 Issue 9368, p1496-1501. 6p. – Name: Abstract Label: Abstract Group: Ab Data: <bold>Background: </bold>Dietary fibre is thought to protect against colorectal cancer but this view has been challenged by recent prospective and intervention studies that showed no protective effect.<bold>Methods: </bold>We prospectively examined the association between dietary fibre intake and incidence of colorectal cancer in 519978 individuals aged 25-70 years taking part in the EPIC study, recruited from ten European countries. Participants completed a dietary questionnaire in 1992-98 and were followed up for cancer incidence. Relative risk estimates were obtained from fibre intake, categorised by sex-specific, cohort-wide quintiles, and from linear models relating the hazard ratio to fibre intake expressed as a continuous variable.<bold>Findings: </bold>Follow-up consisted of 1939011 person-years, and data for 1065 reported cases of colorectal cancer were included in the analysis. Dietary fibre in foods was inversely related to incidence of large bowel cancer (adjusted relative risk 0.75 [95% CI 0.59-0.95] for the highest versus lowest quintile of intake), the protective effect being greatest for the left side of the colon, and least for the rectum. After calibration with more detailed dietary data, the adjusted relative risk for the highest versus lowest quintile of fibre from food intake was 0.58 (0.41-0.85). No food source of fibre was significantly more protective than others, and non-food supplement sources of fibre were not investigated.<bold>Interpretation: </bold>In populations with low average intake of dietary fibre, an approximate doubling of total fibre intake from foods could reduce the risk of colorectal cancer by 40%. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=106874742 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/s0140-6736(03)13174-1 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 1496 Titles: – TitleFull: Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bingham SA – PersonEntity: Name: NameFull: Day NE – PersonEntity: Name: NameFull: Luben R – PersonEntity: Name: NameFull: Ferrari P – PersonEntity: Name: NameFull: Slimani N – PersonEntity: Name: NameFull: Norat T – PersonEntity: Name: NameFull: Clavel-Chapelon F – PersonEntity: Name: NameFull: Kesse E – PersonEntity: Name: NameFull: Nieters A – PersonEntity: Name: NameFull: Boeing H – PersonEntity: Name: NameFull: Tjønneland A – PersonEntity: Name: NameFull: Overvad K – PersonEntity: Name: NameFull: Martinez C – PersonEntity: Name: NameFull: Dorronsoro M – PersonEntity: Name: NameFull: Gonzalez CA – PersonEntity: Name: NameFull: Key TJ – PersonEntity: Name: NameFull: Trichopoulou A – PersonEntity: Name: NameFull: Naska A – PersonEntity: Name: NameFull: Vineis P – PersonEntity: Name: NameFull: Tumino R IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 05 Text: 5/3/2003 Type: published Y: 2003 Identifiers: – Type: issn-print Value: 01406736 Numbering: – Type: volume Value: 361 – Type: issue Value: 9368 Titles: – TitleFull: Lancet Type: main |
| ResultId | 1 |
