The ketogenic diet: a 3- to 6- year follow-up of 150 children enrolled prospectively.
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| Title: | The ketogenic diet: a 3- to 6- year follow-up of 150 children enrolled prospectively. |
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| Authors: | Hemingway C (AUTHOR), Freeman JM (AUTHOR), Pillas DJ (AUTHOR), Pyzik PL (AUTHOR) |
| Source: | Pediatrics. Oct2001, Vol. 108 Issue 4, p898-905. 8p. |
| Abstract: | Objective. To document the long-term outcome of the 83 children with difficult-to-control seizures who were enrolled prospectively in a study of the efficacy of the ketogenic diet and who had remained on the diet for 1 year. Methods. A total of 150 consecutive children were entered prospectively into a study of the ketogenic diet's efficacy and tolerability. Three to 6 years after diet initiation, all 150 families were sent a survey inquiring about their child's current health status, seizure frequency, and current anticonvulsant medications. They were asked about their experience with the diet and reasons for discontinuation. Several telephone attempts were made to contact those who did not respond to the written questionnaire. Responses were entered in an Access database and analyzed. Results. In 1999, 3 to 6 years after initiating the diet, 107 of 150 families responded to a questionnaire. Thirty-five additional families were interviewed by telephone, 4 were lost to follow-up, and 4 children had died, unrelated to the diet. Of the original 150 patient cohort, 20 (13%) were seizure-free and an additional 21 (14%) had a 90% to 99% decrease in their seizures. Twenty-nine were free of medications, and 28 were on only 1 medication; 15 remained on the diet. There were no known cardiac complications. Conclusion. Three to 6 years after initiation, the ketogenic diet had proven to be effective in the control of difficult-to-control seizures in children. The diet often allows decrease or discontinuation of medication. It is more effective than many of the newer anticonvulsants and is well-tolerated when it is effective. [ABSTRACT FROM AUTHOR] |
| Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 106896297 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The ketogenic diet: a 3- to 6- year follow-up of 150 children enrolled prospectively. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hemingway+C%22">Hemingway C</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Freeman+JM%22">Freeman JM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pillas+DJ%22">Pillas DJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pyzik+PL%22">Pyzik PL</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Oct2001, Vol. 108 Issue 4, p898-905. 8p. – Name: Abstract Label: Abstract Group: Ab Data: Objective. To document the long-term outcome of the 83 children with difficult-to-control seizures who were enrolled prospectively in a study of the efficacy of the ketogenic diet and who had remained on the diet for 1 year. Methods. A total of 150 consecutive children were entered prospectively into a study of the ketogenic diet's efficacy and tolerability. Three to 6 years after diet initiation, all 150 families were sent a survey inquiring about their child's current health status, seizure frequency, and current anticonvulsant medications. They were asked about their experience with the diet and reasons for discontinuation. Several telephone attempts were made to contact those who did not respond to the written questionnaire. Responses were entered in an Access database and analyzed. Results. In 1999, 3 to 6 years after initiating the diet, 107 of 150 families responded to a questionnaire. Thirty-five additional families were interviewed by telephone, 4 were lost to follow-up, and 4 children had died, unrelated to the diet. Of the original 150 patient cohort, 20 (13%) were seizure-free and an additional 21 (14%) had a 90% to 99% decrease in their seizures. Twenty-nine were free of medications, and 28 were on only 1 medication; 15 remained on the diet. There were no known cardiac complications. Conclusion. Three to 6 years after initiation, the ketogenic diet had proven to be effective in the control of difficult-to-control seizures in children. The diet often allows decrease or discontinuation of medication. It is more effective than many of the newer anticonvulsants and is well-tolerated when it is effective. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=106896297 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1542/peds.108.4.898 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 898 Titles: – TitleFull: The ketogenic diet: a 3- to 6- year follow-up of 150 children enrolled prospectively. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hemingway C – PersonEntity: Name: NameFull: Freeman JM – PersonEntity: Name: NameFull: Pillas DJ – PersonEntity: Name: NameFull: Pyzik PL IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2001 Type: published Y: 2001 Identifiers: – Type: issn-print Value: 00314005 Numbering: – Type: volume Value: 108 – Type: issue Value: 4 Titles: – TitleFull: Pediatrics Type: main |
| ResultId | 1 |
