Household solvent exposures and childhood acute lymphoblastic leukemia.
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| Title: | Household solvent exposures and childhood acute lymphoblastic leukemia. |
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| Authors: | Freedman DM (AUTHOR), Stewart P (AUTHOR), Kleinerman RA (AUTHOR), Wacholder S (AUTHOR), Hatch EE (AUTHOR), Tarone RE (AUTHOR), Robison LL (AUTHOR), Linet MS (AUTHOR) |
| Source: | American Journal of Public Health. Apr2001, Vol. 91 Issue 4, p564-567. 4p. |
| Subjects: | Lymphoblastic leukemia in children, Leukemia in children, Organic solvents, Mother-child relationship, Juvenile diseases |
| Abstract: | OBJECTIVES: This study explored the risk of childhood acute lymphoblastic leukemia (ALL) associated with participation by household members in hobbies or other home projects involving organic solvents. METHODS: Participants in this case-control study were 640 subjects with ALL and 640 matched controls. RESULTS: Childhood ALL was associated with frequent (> 4 times/month) exposure to model building (odds ratio [OR] = 1.9; 95% confidence interval [95% CI] = 0.7, 5.8) and artwork using solvents (OR = 4.1; 95% CI = 1.1, 15.1). We also found elevated risk (OR = 1.7; 95% CI = 1.1, 2.7) among children whose mothers lived in homes painted extensively (> 4 rooms) in the year before the children's birth. CONCLUSIONS: In this exploratory study, substantial participation by household members in some common household activities that involve organic solvents was associated with elevated risks of childhood ALL. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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