The prevalence of pain in pediatric human immunodeficiency virs/acquired immunodeficiency syndrome as reported by participants in the pediatric late outcomes study (PACTG 219)
Saved in:
| Title: | The prevalence of pain in pediatric human immunodeficiency virs/acquired immunodeficiency syndrome as reported by participants in the pediatric late outcomes study (PACTG 219) |
|---|---|
| Authors: | Gaughan DM (AUTHOR), Hughes MD (AUTHOR), Seage GR III (AUTHOR), Selwyn PA (AUTHOR), Carey VJ (AUTHOR), Gortmaker SL (AUTHOR), Oleske JM (AUTHOR), PACTG 219 Team (CORPORATE AUTHOR) |
| Source: | Pediatrics. Jun2002, Vol. 109 Issue 6, p1144-1152. 9p. |
| Abstract: | OBJECTIVES: As the life expectancy of children with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) increases, quality-of-life outcomes are of increasing concern. The prevalence of pain in adults with AIDS ranges from 40% to 60%, depending on stage of illness. There is limited research concerning pain in HIV-infected children and youth. DESIGN: The General Health Assessment for Children was administered to caregivers of HIV-infected children and youth enrolled in the Pediatric Late Outcomes Study (PACTG 219), a prospective cohort study. Pain is assessed over the previous month with 7 questions. For the purpose of this analysis, we defined pain as the presence of pain of at least moderate intensity. Participants were observed from January 1, 1996, to December 31, 1999. RESULTS: A total of 985 HIV-positive participants had a baseline pain evaluation in 1995. The prevalence of pain remained relatively constant during each year of observation, averaging 20%. Lower CD4+ T-lymphocyte percentage, female gender, and an HIV/AIDS-related diagnosis were highly associated with an increased risk of reported pain. Pain was also independently associated with increased risk of death. After adjusting for CD4 percentage, use of combination therapy including protease inhibitors, comorbid diagnoses, and other sociodemographic characteristics, individuals reporting pain were over 5 times more likely to die than those not reporting pain (hazard ratio = 5.07; 95% confidence interval = 3.23-7.95). CONCLUSIONS: Pain is a frequently encountered symptom in children and youth with HIV disease and is also associated with increased mortality. These findings emphasize the importance of pain management in this population. [ABSTRACT FROM AUTHOR] |
| Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 106959001 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: The prevalence of pain in pediatric human immunodeficiency virs/acquired immunodeficiency syndrome as reported by participants in the pediatric late outcomes study (PACTG 219) – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Gaughan+DM%22">Gaughan DM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hughes+MD%22">Hughes MD</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Seage+GR+III%22">Seage GR III</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Selwyn+PA%22">Selwyn PA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Carey+VJ%22">Carey VJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gortmaker+SL%22">Gortmaker SL</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Oleske+JM%22">Oleske JM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22PACTG+219+Team%22">PACTG 219 Team</searchLink> (CORPORATE AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Jun2002, Vol. 109 Issue 6, p1144-1152. 9p. – Name: Abstract Label: Abstract Group: Ab Data: OBJECTIVES: As the life expectancy of children with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) increases, quality-of-life outcomes are of increasing concern. The prevalence of pain in adults with AIDS ranges from 40% to 60%, depending on stage of illness. There is limited research concerning pain in HIV-infected children and youth. DESIGN: The General Health Assessment for Children was administered to caregivers of HIV-infected children and youth enrolled in the Pediatric Late Outcomes Study (PACTG 219), a prospective cohort study. Pain is assessed over the previous month with 7 questions. For the purpose of this analysis, we defined pain as the presence of pain of at least moderate intensity. Participants were observed from January 1, 1996, to December 31, 1999. RESULTS: A total of 985 HIV-positive participants had a baseline pain evaluation in 1995. The prevalence of pain remained relatively constant during each year of observation, averaging 20%. Lower CD4+ T-lymphocyte percentage, female gender, and an HIV/AIDS-related diagnosis were highly associated with an increased risk of reported pain. Pain was also independently associated with increased risk of death. After adjusting for CD4 percentage, use of combination therapy including protease inhibitors, comorbid diagnoses, and other sociodemographic characteristics, individuals reporting pain were over 5 times more likely to die than those not reporting pain (hazard ratio = 5.07; 95% confidence interval = 3.23-7.95). CONCLUSIONS: Pain is a frequently encountered symptom in children and youth with HIV disease and is also associated with increased mortality. These findings emphasize the importance of pain management in this population. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=106959001 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1542/peds.109.6.1144 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 1144 Titles: – TitleFull: The prevalence of pain in pediatric human immunodeficiency virs/acquired immunodeficiency syndrome as reported by participants in the pediatric late outcomes study (PACTG 219) Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gaughan DM – PersonEntity: Name: NameFull: Hughes MD – PersonEntity: Name: NameFull: Seage GR III – PersonEntity: Name: NameFull: Selwyn PA – PersonEntity: Name: NameFull: Carey VJ – PersonEntity: Name: NameFull: Gortmaker SL – PersonEntity: Name: NameFull: Oleske JM – PersonEntity: Name: NameFull: PACTG 219 Team IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2002 Type: published Y: 2002 Identifiers: – Type: issn-print Value: 00314005 Numbering: – Type: volume Value: 109 – Type: issue Value: 6 Titles: – TitleFull: Pediatrics Type: main |
| ResultId | 1 |
