Leptin levels in restricting and purging anorectics.
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| Title: | Leptin levels in restricting and purging anorectics. |
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| Authors: | Mehler PS (AUTHOR), Eckel RH (AUTHOR), Donohoo WT (AUTHOR) |
| Source: | International Journal of Eating Disorders. Sep1999, Vol. 26 Issue 2, p189-194. 6p. |
| Abstract: | Patients with anorexia nervosa of the restricting (AN-R) and purging (AN-P) subtypes were studied to determine if there was a differential effect on leptin levels. It was hypothesized that the AN-P subgroup would have elevated leptin compared to the AN-R subgroup. Fasting plasma and anthropormorphic measurements were collected from 8 women with AN-R and 5 with AN-P. Eleven women served as controls. Overall, the plasma leptin correlated with body mass index (BMI; R = 0.432, p < .05). The AN-P subgroup had elevated leptin compared to the AN-R subgroup (3.8 +/- 0.8 vs. 1.5 +/- 0.2 ng/ml, p < .05) despite similar BMI (16.0 +/- 0.5 vs. 14.8 +/- 0.8 kg/m2). Additionally, the AN-P subgroup had similar plasma leptins as controls (3.8 +/- 0.8 vs. 3.6 +/- 0.1) despite different BMI (16.0 +/- 0.5 vs. 20.2 +/- 0.2, p < .001). Cortisol in the AN-P subgroup trended to be higher than in the restricting anorectics (21.8 +/- 3.0 vs. 15.6 +/- 1.3, p = .06). In AN, leptin was elevated in AN-P vs. AN. This may be due to increased glucocorticoid stimulation of leptin. [ABSTRACT FROM AUTHOR] |
| Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 107229745 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Leptin levels in restricting and purging anorectics. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Mehler+PS%22">Mehler PS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Eckel+RH%22">Eckel RH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Donohoo+WT%22">Donohoo WT</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Eating+Disorders%22">International Journal of Eating Disorders</searchLink>. Sep1999, Vol. 26 Issue 2, p189-194. 6p. – Name: Abstract Label: Abstract Group: Ab Data: Patients with anorexia nervosa of the restricting (AN-R) and purging (AN-P) subtypes were studied to determine if there was a differential effect on leptin levels. It was hypothesized that the AN-P subgroup would have elevated leptin compared to the AN-R subgroup. Fasting plasma and anthropormorphic measurements were collected from 8 women with AN-R and 5 with AN-P. Eleven women served as controls. Overall, the plasma leptin correlated with body mass index (BMI; R = 0.432, p < .05). The AN-P subgroup had elevated leptin compared to the AN-R subgroup (3.8 +/- 0.8 vs. 1.5 +/- 0.2 ng/ml, p < .05) despite similar BMI (16.0 +/- 0.5 vs. 14.8 +/- 0.8 kg/m2). Additionally, the AN-P subgroup had similar plasma leptins as controls (3.8 +/- 0.8 vs. 3.6 +/- 0.1) despite different BMI (16.0 +/- 0.5 vs. 20.2 +/- 0.2, p < .001). Cortisol in the AN-P subgroup trended to be higher than in the restricting anorectics (21.8 +/- 3.0 vs. 15.6 +/- 1.3, p = .06). In AN, leptin was elevated in AN-P vs. AN. This may be due to increased glucocorticoid stimulation of leptin. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=107229745 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/(sici)1098-108x(199909)26:2<189::aid-eat8>3.0.co;2-v Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 189 Titles: – TitleFull: Leptin levels in restricting and purging anorectics. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mehler PS – PersonEntity: Name: NameFull: Eckel RH – PersonEntity: Name: NameFull: Donohoo WT IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep1999 Type: published Y: 1999 Identifiers: – Type: issn-print Value: 02763478 Numbering: – Type: volume Value: 26 – Type: issue Value: 2 Titles: – TitleFull: International Journal of Eating Disorders Type: main |
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