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The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.

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Title: The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.
Authors: Seage GR III (AUTHOR), Gatsonis C (AUTHOR), Weissman JS (AUTHOR), Haas JS (AUTHOR), Cleary PD (AUTHOR), Fowler FJ (AUTHOR), Massagli MP (AUTHOR), Stone VE (AUTHOR), Craven DE (AUTHOR), Makadon H (AUTHOR), Goldberg J (AUTHOR), Coltin K (AUTHOR), Levin KS (AUTHOR), Epstein AM (AUTHOR)
Source: American Journal of Public Health. Apr97, Vol. 87 Issue 4, p567-573. 7p.
Subjects: AIDS patients, HIV-positive persons, Public health, Medical records
Geographic Terms: Boston (Mass.), Massachusetts
Abstract: OBJECTIVES: This study developed a new acquired immunodeficiency syndrome (AIDS) severity system by including diagnostic, physiological, functional, and sociodemographic factors predictive of survival. METHODS: Three-hundred five persons with AIDS in Boston were interviewed; their medical records were reviewed and vital status ascertained. RESULTS: Overall median (+/- SD) survival for the cohort from the first interview until death was 560 +/- 14.4 days. The best model for predicting survival, the Boston AIDS Survival Score, included the Justice score (stage 2 relative hazard [RH] = 1.25, 95% confidence interval [CI] = 0.80, 1.96; stage 3 RH = 1.76, 95% CI = 1.15, 2.70), a newly developed opportunistic disease score (Boston Opportunistic Disease Survival Score; stage 2 RH = 1.35, 95% CI = 0.90, 2.02; stage 3 RH = 2.10, 95% CI = 1.38, 3.18), and measures of activities of daily living (any intermediate limitations, RH = 1.84, 95% CI = 1.05, 3.21; any basic limitations, RH = 2.60, 95% CI = 1.44, 4.69). This model had substantially greater predictive power (R2 = .17, C statistic = .68) than the Justice score alone (R2 = .09, C statistic = .61). CONCLUSIONS: Incorporating data on clinically important events and functional status into a physiologically based system can improve the prediction of survival with AIDS. [ABSTRACT FROM AUTHOR]
Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument.
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  Data: <searchLink fieldCode="AR" term="%22Seage+GR+III%22">Seage GR III</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gatsonis+C%22">Gatsonis C</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Weissman+JS%22">Weissman JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Haas+JS%22">Haas JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cleary+PD%22">Cleary PD</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fowler+FJ%22">Fowler FJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Massagli+MP%22">Massagli MP</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Stone+VE%22">Stone VE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Craven+DE%22">Craven DE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Makadon+H%22">Makadon H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Goldberg+J%22">Goldberg J</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Coltin+K%22">Coltin K</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Levin+KS%22">Levin KS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Epstein+AM%22">Epstein AM</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Public+Health%22">American Journal of Public Health</searchLink>. Apr97, Vol. 87 Issue 4, p567-573. 7p.
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  Data: <searchLink fieldCode="DE" term="%22AIDS+patients%22">AIDS patients</searchLink><br /><searchLink fieldCode="DE" term="%22HIV-positive+persons%22">HIV-positive persons</searchLink><br /><searchLink fieldCode="DE" term="%22Public+health%22">Public health</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+records%22">Medical records</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Boston+%28Mass%2E%29%22">Boston (Mass.)</searchLink><br /><searchLink fieldCode="DE" term="%22Massachusetts%22">Massachusetts</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: OBJECTIVES: This study developed a new acquired immunodeficiency syndrome (AIDS) severity system by including diagnostic, physiological, functional, and sociodemographic factors predictive of survival. METHODS: Three-hundred five persons with AIDS in Boston were interviewed; their medical records were reviewed and vital status ascertained. RESULTS: Overall median (+/- SD) survival for the cohort from the first interview until death was 560 +/- 14.4 days. The best model for predicting survival, the Boston AIDS Survival Score, included the Justice score (stage 2 relative hazard [RH] = 1.25, 95% confidence interval [CI] = 0.80, 1.96; stage 3 RH = 1.76, 95% CI = 1.15, 2.70), a newly developed opportunistic disease score (Boston Opportunistic Disease Survival Score; stage 2 RH = 1.35, 95% CI = 0.90, 2.02; stage 3 RH = 2.10, 95% CI = 1.38, 3.18), and measures of activities of daily living (any intermediate limitations, RH = 1.84, 95% CI = 1.05, 3.21; any basic limitations, RH = 2.60, 95% CI = 1.44, 4.69). This model had substantially greater predictive power (R2 = .17, C statistic = .68) than the Justice score alone (R2 = .09, C statistic = .61). CONCLUSIONS: Incorporating data on clinically important events and functional status into a physiologically based system can improve the prediction of survival with AIDS. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.2105/AJPH.87.4.567
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 567
    Subjects:
      – SubjectFull: AIDS patients
        Type: general
      – SubjectFull: HIV-positive persons
        Type: general
      – SubjectFull: Public health
        Type: general
      – SubjectFull: Medical records
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      – SubjectFull: Boston (Mass.)
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      – SubjectFull: Massachusetts
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              Text: Apr97
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              Y: 1997
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