HIV-1 neutralizing antibodies induced by native-like envelope trimers.
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| Title: | HIV-1 neutralizing antibodies induced by native-like envelope trimers. |
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| Authors: | Sanders, Rogier W., van Gils, Marit J., Derking, Ronald, Sok, Devin, Ketas, Thomas J., Burger, Judith A., Ozorowski, Gabriel, Cupo, Albert, Simonich, Cassandra, Goo, Leslie, Arendt, Heather, Kim, Helen J., Jeong Hyun Lee, Pugacli, Pavel, Williams, Melissa, Debnath, Gargi, Moldt, Brian, van Breemen, Marielle J., Isik, Gozde, Medina-Ramirez, Max |
| Source: | Science (pre-March 2025). 7/10/2015, Vol. 349 Issue 6244, p154-154. 1p. |
| Subjects: | AIDS vaccination research, Glycoproteins, Recombinant antibodies, Immunoglobulins, Immunoglobulin synthesis |
| Abstract: | The article discusses research the induction of HIV-1 broadly neutralizing antibodies (bNAbs) through the identification of immunogens on the basis of an envelope glycoprotein (Env). Topics include the testing of the vaccine in rabbits and macaques, the use of native-like envelope trimers, and the potential for the development of recombinant Env immunogens. |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 108366406 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: HIV-1 neutralizing antibodies induced by native-like envelope trimers. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sanders%2C+Rogier+W%2E%22">Sanders, Rogier W.</searchLink><br /><searchLink fieldCode="AR" term="%22van+Gils%2C+Marit+J%2E%22">van Gils, Marit J.</searchLink><br /><searchLink fieldCode="AR" term="%22Derking%2C+Ronald%22">Derking, Ronald</searchLink><br /><searchLink fieldCode="AR" term="%22Sok%2C+Devin%22">Sok, Devin</searchLink><br /><searchLink fieldCode="AR" term="%22Ketas%2C+Thomas+J%2E%22">Ketas, Thomas J.</searchLink><br /><searchLink fieldCode="AR" term="%22Burger%2C+Judith+A%2E%22">Burger, Judith A.</searchLink><br /><searchLink fieldCode="AR" term="%22Ozorowski%2C+Gabriel%22">Ozorowski, Gabriel</searchLink><br /><searchLink fieldCode="AR" term="%22Cupo%2C+Albert%22">Cupo, Albert</searchLink><br /><searchLink fieldCode="AR" term="%22Simonich%2C+Cassandra%22">Simonich, Cassandra</searchLink><br /><searchLink fieldCode="AR" term="%22Goo%2C+Leslie%22">Goo, Leslie</searchLink><br /><searchLink fieldCode="AR" term="%22Arendt%2C+Heather%22">Arendt, Heather</searchLink><br /><searchLink fieldCode="AR" term="%22Kim%2C+Helen+J%2E%22">Kim, Helen J.</searchLink><br /><searchLink fieldCode="AR" term="%22Jeong+Hyun+Lee%22">Jeong Hyun Lee</searchLink><br /><searchLink fieldCode="AR" term="%22Pugacli%2C+Pavel%22">Pugacli, Pavel</searchLink><br /><searchLink fieldCode="AR" term="%22Williams%2C+Melissa%22">Williams, Melissa</searchLink><br /><searchLink fieldCode="AR" term="%22Debnath%2C+Gargi%22">Debnath, Gargi</searchLink><br /><searchLink fieldCode="AR" term="%22Moldt%2C+Brian%22">Moldt, Brian</searchLink><br /><searchLink fieldCode="AR" term="%22van+Breemen%2C+Marielle+J%2E%22">van Breemen, Marielle J.</searchLink><br /><searchLink fieldCode="AR" term="%22Isik%2C+Gozde%22">Isik, Gozde</searchLink><br /><searchLink fieldCode="AR" term="%22Medina-Ramirez%2C+Max%22">Medina-Ramirez, Max</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Science+%28pre-March+2025%29%22">Science (pre-March 2025)</searchLink>. 7/10/2015, Vol. 349 Issue 6244, p154-154. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22AIDS+vaccination+research%22">AIDS vaccination research</searchLink><br /><searchLink fieldCode="DE" term="%22Glycoproteins%22">Glycoproteins</searchLink><br /><searchLink fieldCode="DE" term="%22Recombinant+antibodies%22">Recombinant antibodies</searchLink><br /><searchLink fieldCode="DE" term="%22Immunoglobulins%22">Immunoglobulins</searchLink><br /><searchLink fieldCode="DE" term="%22Immunoglobulin+synthesis%22">Immunoglobulin synthesis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The article discusses research the induction of HIV-1 broadly neutralizing antibodies (bNAbs) through the identification of immunogens on the basis of an envelope glycoprotein (Env). Topics include the testing of the vaccine in rabbits and macaques, the use of native-like envelope trimers, and the potential for the development of recombinant Env immunogens. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=108366406 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/science.aac4223 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: 154 Subjects: – SubjectFull: AIDS vaccination research Type: general – SubjectFull: Glycoproteins Type: general – SubjectFull: Recombinant antibodies Type: general – SubjectFull: Immunoglobulins Type: general – SubjectFull: Immunoglobulin synthesis Type: general Titles: – TitleFull: HIV-1 neutralizing antibodies induced by native-like envelope trimers. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sanders, Rogier W. – PersonEntity: Name: NameFull: van Gils, Marit J. – PersonEntity: Name: NameFull: Derking, Ronald – PersonEntity: Name: NameFull: Sok, Devin – PersonEntity: Name: NameFull: Ketas, Thomas J. – PersonEntity: Name: NameFull: Burger, Judith A. – PersonEntity: Name: NameFull: Ozorowski, Gabriel – PersonEntity: Name: NameFull: Cupo, Albert – PersonEntity: Name: NameFull: Simonich, Cassandra – PersonEntity: Name: NameFull: Goo, Leslie – PersonEntity: Name: NameFull: Arendt, Heather – PersonEntity: Name: NameFull: Kim, Helen J. – PersonEntity: Name: NameFull: Jeong Hyun Lee – PersonEntity: Name: NameFull: Pugacli, Pavel – PersonEntity: Name: NameFull: Williams, Melissa – PersonEntity: Name: NameFull: Debnath, Gargi – PersonEntity: Name: NameFull: Moldt, Brian – PersonEntity: Name: NameFull: van Breemen, Marielle J. – PersonEntity: Name: NameFull: Isik, Gozde – PersonEntity: Name: NameFull: Medina-Ramirez, Max IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 07 Text: 7/10/2015 Type: published Y: 2015 Identifiers: – Type: issn-print Value: 00368075 Numbering: – Type: volume Value: 349 – Type: issue Value: 6244 Titles: – TitleFull: Science (pre-March 2025) Type: main |
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