HIV-1 neutralizing antibodies induced by native-like envelope trimers.
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| Title: | HIV-1 neutralizing antibodies induced by native-like envelope trimers. |
|---|---|
| Authors: | Sanders, Rogier W., van Gils, Marit J., Derking, Ronald, Sok, Devin, Ketas, Thomas J., Burger, Judith A., Ozorowski, Gabriel, Cupo, Albert, Simonich, Cassandra, Goo, Leslie, Arendt, Heather, Kim, Helen J., Jeong Hyun Lee, Pugacli, Pavel, Williams, Melissa, Debnath, Gargi, Moldt, Brian, van Breemen, Marielle J., Isik, Gozde, Medina-Ramirez, Max |
| Source: | Science (pre-March 2025). 7/10/2015, Vol. 349 Issue 6244, p154-154. 1p. |
| Subjects: | AIDS vaccination research, Glycoproteins, Recombinant antibodies, Immunoglobulins, Immunoglobulin synthesis |
| Abstract: | The article discusses research the induction of HIV-1 broadly neutralizing antibodies (bNAbs) through the identification of immunogens on the basis of an envelope glycoprotein (Env). Topics include the testing of the vaccine in rabbits and macaques, the use of native-like envelope trimers, and the potential for the development of recombinant Env immunogens. |
| Database: | Psychology and Behavioral Sciences Collection |
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