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Age and education adjusted normative data and discriminative validity for Rey’s Auditory Verbal Learning Test in the elderly Greek population.

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Title: Age and education adjusted normative data and discriminative validity for Rey’s Auditory Verbal Learning Test in the elderly Greek population.
Authors: Messinis, Lambros (AUTHOR), Nasios, Grigorios (AUTHOR), Mougias, Antonios (AUTHOR), Politis, Antonis (AUTHOR), Zampakis, Petros (AUTHOR), Tsiamaki, Eirini (AUTHOR), Malefaki, Sonia (AUTHOR), Gourzis, Phillipos (AUTHOR), Papathanasopoulos, Panagiotis (AUTHOR)
Source: Journal of Clinical & Experimental Neuropsychology. Jan2016, Vol. 38 Issue 1, p23-39. 17p. 3 Diagrams, 3 Charts, 1 Graph.
Subjects: Neuropsychological tests, Episodic memory, Older people, Sociodemographic factors, Receiver operating characteristic curves
Geographic Terms: Greece
Abstract: Rey’s Auditory Verbal Learning Test (RAVLT) is a widely used neuropsychological test to assess episodic memory. In the present study we sought to establish normative and discriminative validity data for the RAVLT in the elderly population using previously adapted learning lists for the Greek adult population. We administered the test to 258 cognitively healthy elderly participants, aged 60–89 years, and two patient groups (192 with amnestic mild cognitive impairment, aMCI, and 65 with Alzheimer’s disease, AD). From the statistical analyses, we found that age and education contributed significantly to most trials of the RAVLT, whereas the influence of gender was not significant. Younger elderly participants with higher education outperformed the older elderly with lower education levels. Moreover, both clinical groups performed significantly worse on most RAVLT trials and composite measures than matched cognitively healthy controls. Furthermore, the AD group performed more poorly than the aMCI group on most RAVLT variables. Receiver operating characteristic (ROC) analysis was used to examine the utility of the RAVLT trials to discriminate cognitively healthy controls from aMCI and AD patients. Area under the curve (AUC), an index of effect size, showed that most of the RAVLT measures (individual and composite) included in this study adequately differentiated between the performance of healthy elders and aMCI/AD patients. We also provide cutoff scores in discriminating cognitively healthy controls from aMCI and AD patients, based on the sensitivity and specificity of the prescribed scores. Moreover, we present age- and education-specific normative data for individual and composite scores for the Greek adapted RAVLT in elderly subjects aged between 60 and 89 years for use in clinical and research settings. [ABSTRACT FROM PUBLISHER]
Copyright of Journal of Clinical & Experimental Neuropsychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Age and education adjusted normative data and discriminative validity for Rey’s Auditory Verbal Learning Test in the elderly Greek population.
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  Data: <searchLink fieldCode="AR" term="%22Messinis%2C+Lambros%22">Messinis, Lambros</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nasios%2C+Grigorios%22">Nasios, Grigorios</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mougias%2C+Antonios%22">Mougias, Antonios</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Politis%2C+Antonis%22">Politis, Antonis</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zampakis%2C+Petros%22">Zampakis, Petros</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tsiamaki%2C+Eirini%22">Tsiamaki, Eirini</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Malefaki%2C+Sonia%22">Malefaki, Sonia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gourzis%2C+Phillipos%22">Gourzis, Phillipos</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Papathanasopoulos%2C+Panagiotis%22">Papathanasopoulos, Panagiotis</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Clinical+%26+Experimental+Neuropsychology%22">Journal of Clinical & Experimental Neuropsychology</searchLink>. Jan2016, Vol. 38 Issue 1, p23-39. 17p. 3 Diagrams, 3 Charts, 1 Graph.
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  Data: <searchLink fieldCode="DE" term="%22Neuropsychological+tests%22">Neuropsychological tests</searchLink><br /><searchLink fieldCode="DE" term="%22Episodic+memory%22">Episodic memory</searchLink><br /><searchLink fieldCode="DE" term="%22Older+people%22">Older people</searchLink><br /><searchLink fieldCode="DE" term="%22Sociodemographic+factors%22">Sociodemographic factors</searchLink><br /><searchLink fieldCode="DE" term="%22Receiver+operating+characteristic+curves%22">Receiver operating characteristic curves</searchLink>
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  Data: Rey’s Auditory Verbal Learning Test (RAVLT) is a widely used neuropsychological test to assess episodic memory. In the present study we sought to establish normative and discriminative validity data for the RAVLT in the elderly population using previously adapted learning lists for the Greek adult population. We administered the test to 258 cognitively healthy elderly participants, aged 60–89 years, and two patient groups (192 with amnestic mild cognitive impairment, aMCI, and 65 with Alzheimer’s disease, AD). From the statistical analyses, we found that age and education contributed significantly to most trials of the RAVLT, whereas the influence of gender was not significant. Younger elderly participants with higher education outperformed the older elderly with lower education levels. Moreover, both clinical groups performed significantly worse on most RAVLT trials and composite measures than matched cognitively healthy controls. Furthermore, the AD group performed more poorly than the aMCI group on most RAVLT variables. Receiver operating characteristic (ROC) analysis was used to examine the utility of the RAVLT trials to discriminate cognitively healthy controls from aMCI and AD patients. Area under the curve (AUC), an index of effect size, showed that most of the RAVLT measures (individual and composite) included in this study adequately differentiated between the performance of healthy elders and aMCI/AD patients. We also provide cutoff scores in discriminating cognitively healthy controls from aMCI and AD patients, based on the sensitivity and specificity of the prescribed scores. Moreover, we present age- and education-specific normative data for individual and composite scores for the Greek adapted RAVLT in elderly subjects aged between 60 and 89 years for use in clinical and research settings. [ABSTRACT FROM PUBLISHER]
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  Data: <i>Copyright of Journal of Clinical & Experimental Neuropsychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – SubjectFull: Older people
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      – SubjectFull: Sociodemographic factors
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      – SubjectFull: Greece
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              Text: Jan2016
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