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Synergistic effect between back pain and common mental disorders and the risk of future disability pension: a nationwide study from Sweden.

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Title: Synergistic effect between back pain and common mental disorders and the risk of future disability pension: a nationwide study from Sweden.
Authors: Dorner, T. E., Alexanderson, K., Svedberg, P., Tinghög, P., Ropponen, A., Mittendorfer-Rutz, E.
Source: Psychological Medicine. Jan2016, Vol. 46 Issue 2, p425-436. 12p.
Subjects: Backache, Confidence intervals, Mental depression, Reporting of diseases, Disability insurance, Longitudinal method, Mental illness, Pensions, Probability theory, Research funding, Risk assessment, Sick leave, Surveys, Mathematical variables, Comorbidity, Educational attainment
Geographic Terms: Sweden
Abstract: Background. The aim of this study was to analyse a possible synergistic effect between back pain and common mental disorders (CMDs) in relation to future disability pension (DP). Method. All 4 823 069 individuals aged 16-64 years, living in Sweden in December 2004, not pensioned in 2005 and without ongoing sickness absence at the turn of 2004/2005 formed the cohort of this register-based study. Hazard ratios (HRs) and 95% confidence intervals (CIs) for DP (2006-2010) were estimated. Exposure variables were back pain (M54) (sickness absence or inpatient or specialized outpatient care in 2005) and CMD (F40-F48) [sickness absence or inpatient or specialized outpatient care or antidepressants (N06a) in 2005]. Results. HRs for DP were 4.03 (95% CI 3.87-4.21) and 3.86 (95% CI 3.68-4.04) in women and men with back pain. HRs for DP in women and men with CMD were 4.98 (95% CI 4.88-5.08) and 6.05 (95% CI 5.90-6.21). In women and men with both conditions, HRs for DP were 15.62 (95% CI 14.40-16.94) and 19.84 (95% CI 17.94-21.94). In women, synergy index, relative excess risk due to interaction, and attributable proportion were 1.24 (95% CI 1.13-1.36), 0.18 (95% CI 0.11-0.25), and 2.08 (95% CI 1.09-3.06). The corresponding figures for men were 1.45 (95% CI 1.29-1.62), 0.29 (95% CI 0.22-0.36), and 4.21 (95% CI 2.71-5.70). Conclusions. Co-morbidity of back pain and CMD is associated with a higher risk of DP than either individual condition, when added up, which has possible clinical implications to prevent further disability and exclusion from the labour market. [ABSTRACT FROM AUTHOR]
Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Synergistic effect between back pain and common mental disorders and the risk of future disability pension: a nationwide study from Sweden.
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  Data: <searchLink fieldCode="AR" term="%22Dorner%2C+T%2E+E%2E%22">Dorner, T. E.</searchLink><br /><searchLink fieldCode="AR" term="%22Alexanderson%2C+K%2E%22">Alexanderson, K.</searchLink><br /><searchLink fieldCode="AR" term="%22Svedberg%2C+P%2E%22">Svedberg, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Tinghög%2C+P%2E%22">Tinghög, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Ropponen%2C+A%2E%22">Ropponen, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Mittendorfer-Rutz%2C+E%2E%22">Mittendorfer-Rutz, E.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Psychological+Medicine%22">Psychological Medicine</searchLink>. Jan2016, Vol. 46 Issue 2, p425-436. 12p.
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  Data: <searchLink fieldCode="DE" term="%22Sweden%22">Sweden</searchLink>
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  Data: Background. The aim of this study was to analyse a possible synergistic effect between back pain and common mental disorders (CMDs) in relation to future disability pension (DP). Method. All 4 823 069 individuals aged 16-64 years, living in Sweden in December 2004, not pensioned in 2005 and without ongoing sickness absence at the turn of 2004/2005 formed the cohort of this register-based study. Hazard ratios (HRs) and 95% confidence intervals (CIs) for DP (2006-2010) were estimated. Exposure variables were back pain (M54) (sickness absence or inpatient or specialized outpatient care in 2005) and CMD (F40-F48) [sickness absence or inpatient or specialized outpatient care or antidepressants (N06a) in 2005]. Results. HRs for DP were 4.03 (95% CI 3.87-4.21) and 3.86 (95% CI 3.68-4.04) in women and men with back pain. HRs for DP in women and men with CMD were 4.98 (95% CI 4.88-5.08) and 6.05 (95% CI 5.90-6.21). In women and men with both conditions, HRs for DP were 15.62 (95% CI 14.40-16.94) and 19.84 (95% CI 17.94-21.94). In women, synergy index, relative excess risk due to interaction, and attributable proportion were 1.24 (95% CI 1.13-1.36), 0.18 (95% CI 0.11-0.25), and 2.08 (95% CI 1.09-3.06). The corresponding figures for men were 1.45 (95% CI 1.29-1.62), 0.29 (95% CI 0.22-0.36), and 4.21 (95% CI 2.71-5.70). Conclusions. Co-morbidity of back pain and CMD is associated with a higher risk of DP than either individual condition, when added up, which has possible clinical implications to prevent further disability and exclusion from the labour market. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1017/S003329171500197X
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      – Code: eng
        Text: English
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        PageCount: 12
        StartPage: 425
    Subjects:
      – SubjectFull: Backache
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Reporting of diseases
        Type: general
      – SubjectFull: Disability insurance
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      – SubjectFull: Longitudinal method
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      – SubjectFull: Mental illness
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      – SubjectFull: Pensions
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      – SubjectFull: Research funding
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      – SubjectFull: Risk assessment
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      – SubjectFull: Sick leave
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      – SubjectFull: Surveys
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      – SubjectFull: Mathematical variables
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      – SubjectFull: Educational attainment
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      – SubjectFull: Sweden
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              Text: Jan2016
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