Synergistic effect between back pain and common mental disorders and the risk of future disability pension: a nationwide study from Sweden.

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Bibliographic Details
Title: Synergistic effect between back pain and common mental disorders and the risk of future disability pension: a nationwide study from Sweden.
Authors: Dorner, T. E., Alexanderson, K., Svedberg, P., Tinghög, P., Ropponen, A., Mittendorfer-Rutz, E.
Source: Psychological Medicine. Jan2016, Vol. 46 Issue 2, p425-436. 12p.
Subjects: Backache, Confidence intervals, Mental depression, Reporting of diseases, Disability insurance, Longitudinal method, Mental illness, Pensions, Probability theory, Research funding, Risk assessment, Sick leave, Surveys, Mathematical variables, Comorbidity, Educational attainment
Geographic Terms: Sweden
Abstract: Background. The aim of this study was to analyse a possible synergistic effect between back pain and common mental disorders (CMDs) in relation to future disability pension (DP). Method. All 4 823 069 individuals aged 16-64 years, living in Sweden in December 2004, not pensioned in 2005 and without ongoing sickness absence at the turn of 2004/2005 formed the cohort of this register-based study. Hazard ratios (HRs) and 95% confidence intervals (CIs) for DP (2006-2010) were estimated. Exposure variables were back pain (M54) (sickness absence or inpatient or specialized outpatient care in 2005) and CMD (F40-F48) [sickness absence or inpatient or specialized outpatient care or antidepressants (N06a) in 2005]. Results. HRs for DP were 4.03 (95% CI 3.87-4.21) and 3.86 (95% CI 3.68-4.04) in women and men with back pain. HRs for DP in women and men with CMD were 4.98 (95% CI 4.88-5.08) and 6.05 (95% CI 5.90-6.21). In women and men with both conditions, HRs for DP were 15.62 (95% CI 14.40-16.94) and 19.84 (95% CI 17.94-21.94). In women, synergy index, relative excess risk due to interaction, and attributable proportion were 1.24 (95% CI 1.13-1.36), 0.18 (95% CI 0.11-0.25), and 2.08 (95% CI 1.09-3.06). The corresponding figures for men were 1.45 (95% CI 1.29-1.62), 0.29 (95% CI 0.22-0.36), and 4.21 (95% CI 2.71-5.70). Conclusions. Co-morbidity of back pain and CMD is associated with a higher risk of DP than either individual condition, when added up, which has possible clinical implications to prevent further disability and exclusion from the labour market. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
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