Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study.

Saved in:
Bibliographic Details
Title: Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study.
Authors: Tondo, L., Vázquez, G. H., Baethge, C., Baronessa, C., Bolzani, L., Koukopoulos, A., Mazzarini, L., Murru, A., Pacchiarotti, I., Pinna, M., Salvatore, P., Sani, G., Selle, V., Spalletta, G., Girardi, P., Tohen, M., Vieta, E., Baldessarini, R. J.
Source: Acta Psychiatrica Scandinavica. Jan2016, Vol. 133 Issue 1, p34-43. 10p. 5 Charts, 1 Graph.
Subjects: Bipolar disorder, Schizophrenia, Nosology, Sociodemographic factors, Suicidal ideation, Multivariate analysis
Abstract: Objective Nosological distinctions among schizoaffective disorder ( SA), bipolar I disorder with psychotic features ( BDp), and schizophrenia ( SZ) remain unresolved. Method We compared 2269 subjects with psychotic features in DSM- IV- TR diagnoses (1435 BDp, 463 SZ, 371 SA) from 8 collaborating international sites, by 12 sociodemographic and clinical measures, all between diagnostic pairs. Results In bivariate comparisons, SA was consistently intermediate between BDp and SZ for 11/12 features (except onset stressors), and SZ vs. BDp differed in all 12 factors. SA differed from both BDp and SZ in 9/12 factors: SA and BDp were similar in education and suicidal ideation or acts; SA and SZ were similar in education, onset stressors, and substance abuse. Meta-analytic comparisons of diagnostic pairs for 10 categorical factors indicated similar differences of SA from both SZ and BDp. Multivariate modeling indicated significantly independent differences between BDp and SZ (8 factors), SA vs. SZ (5), and BDp vs. SA (3). Measurement variance was similar for all diagnoses. Conclusion SA was consistently intermediate between BDp and SZ. The three diagnostic groups ranked: BDp > SA > SZ related to lesser morbidity or disability. The findings are not consistent with a dyadic Kraepelinian categorization, although the considerable overlap among the three DSM- IV diagnostic groups indicates uncertain boundaries if they represent distinct disorders. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 112334015
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Tondo%2C+L%2E%22">Tondo, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Vázquez%2C+G%2E+H%2E%22">Vázquez, G. H.</searchLink><br /><searchLink fieldCode="AR" term="%22Baethge%2C+C%2E%22">Baethge, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Baronessa%2C+C%2E%22">Baronessa, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Bolzani%2C+L%2E%22">Bolzani, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Koukopoulos%2C+A%2E%22">Koukopoulos, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Mazzarini%2C+L%2E%22">Mazzarini, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Murru%2C+A%2E%22">Murru, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Pacchiarotti%2C+I%2E%22">Pacchiarotti, I.</searchLink><br /><searchLink fieldCode="AR" term="%22Pinna%2C+M%2E%22">Pinna, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Salvatore%2C+P%2E%22">Salvatore, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Sani%2C+G%2E%22">Sani, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Selle%2C+V%2E%22">Selle, V.</searchLink><br /><searchLink fieldCode="AR" term="%22Spalletta%2C+G%2E%22">Spalletta, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Girardi%2C+P%2E%22">Girardi, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Tohen%2C+M%2E%22">Tohen, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Vieta%2C+E%2E%22">Vieta, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Baldessarini%2C+R%2E+J%2E%22">Baldessarini, R. J.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Jan2016, Vol. 133 Issue 1, p34-43. 10p. 5 Charts, 1 Graph.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Bipolar+disorder%22">Bipolar disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Schizophrenia%22">Schizophrenia</searchLink><br /><searchLink fieldCode="DE" term="%22Nosology%22">Nosology</searchLink><br /><searchLink fieldCode="DE" term="%22Sociodemographic+factors%22">Sociodemographic factors</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+ideation%22">Suicidal ideation</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective Nosological distinctions among schizoaffective disorder ( SA), bipolar I disorder with psychotic features ( BDp), and schizophrenia ( SZ) remain unresolved. Method We compared 2269 subjects with psychotic features in DSM- IV- TR diagnoses (1435 BDp, 463 SZ, 371 SA) from 8 collaborating international sites, by 12 sociodemographic and clinical measures, all between diagnostic pairs. Results In bivariate comparisons, SA was consistently intermediate between BDp and SZ for 11/12 features (except onset stressors), and SZ vs. BDp differed in all 12 factors. SA differed from both BDp and SZ in 9/12 factors: SA and BDp were similar in education and suicidal ideation or acts; SA and SZ were similar in education, onset stressors, and substance abuse. Meta-analytic comparisons of diagnostic pairs for 10 categorical factors indicated similar differences of SA from both SZ and BDp. Multivariate modeling indicated significantly independent differences between BDp and SZ (8 factors), SA vs. SZ (5), and BDp vs. SA (3). Measurement variance was similar for all diagnoses. Conclusion SA was consistently intermediate between BDp and SZ. The three diagnostic groups ranked: BDp > SA > SZ related to lesser morbidity or disability. The findings are not consistent with a dyadic Kraepelinian categorization, although the considerable overlap among the three DSM- IV diagnostic groups indicates uncertain boundaries if they represent distinct disorders. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=112334015
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/acps.12447
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 10
        StartPage: 34
    Subjects:
      – SubjectFull: Bipolar disorder
        Type: general
      – SubjectFull: Schizophrenia
        Type: general
      – SubjectFull: Nosology
        Type: general
      – SubjectFull: Sociodemographic factors
        Type: general
      – SubjectFull: Suicidal ideation
        Type: general
      – SubjectFull: Multivariate analysis
        Type: general
    Titles:
      – TitleFull: Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Tondo, L.
      – PersonEntity:
          Name:
            NameFull: Vázquez, G. H.
      – PersonEntity:
          Name:
            NameFull: Baethge, C.
      – PersonEntity:
          Name:
            NameFull: Baronessa, C.
      – PersonEntity:
          Name:
            NameFull: Bolzani, L.
      – PersonEntity:
          Name:
            NameFull: Koukopoulos, A.
      – PersonEntity:
          Name:
            NameFull: Mazzarini, L.
      – PersonEntity:
          Name:
            NameFull: Murru, A.
      – PersonEntity:
          Name:
            NameFull: Pacchiarotti, I.
      – PersonEntity:
          Name:
            NameFull: Pinna, M.
      – PersonEntity:
          Name:
            NameFull: Salvatore, P.
      – PersonEntity:
          Name:
            NameFull: Sani, G.
      – PersonEntity:
          Name:
            NameFull: Selle, V.
      – PersonEntity:
          Name:
            NameFull: Spalletta, G.
      – PersonEntity:
          Name:
            NameFull: Girardi, P.
      – PersonEntity:
          Name:
            NameFull: Tohen, M.
      – PersonEntity:
          Name:
            NameFull: Vieta, E.
      – PersonEntity:
          Name:
            NameFull: Baldessarini, R. J.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: Jan2016
              Type: published
              Y: 2016
          Identifiers:
            – Type: issn-print
              Value: 0001690X
          Numbering:
            – Type: volume
              Value: 133
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Acta Psychiatrica Scandinavica
              Type: main
ResultId 1