Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study.
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| Title: | Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study. |
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| Authors: | Tondo, L., Vázquez, G. H., Baethge, C., Baronessa, C., Bolzani, L., Koukopoulos, A., Mazzarini, L., Murru, A., Pacchiarotti, I., Pinna, M., Salvatore, P., Sani, G., Selle, V., Spalletta, G., Girardi, P., Tohen, M., Vieta, E., Baldessarini, R. J. |
| Source: | Acta Psychiatrica Scandinavica. Jan2016, Vol. 133 Issue 1, p34-43. 10p. 5 Charts, 1 Graph. |
| Subjects: | Bipolar disorder, Schizophrenia, Nosology, Sociodemographic factors, Suicidal ideation, Multivariate analysis |
| Abstract: | Objective Nosological distinctions among schizoaffective disorder ( SA), bipolar I disorder with psychotic features ( BDp), and schizophrenia ( SZ) remain unresolved. Method We compared 2269 subjects with psychotic features in DSM- IV- TR diagnoses (1435 BDp, 463 SZ, 371 SA) from 8 collaborating international sites, by 12 sociodemographic and clinical measures, all between diagnostic pairs. Results In bivariate comparisons, SA was consistently intermediate between BDp and SZ for 11/12 features (except onset stressors), and SZ vs. BDp differed in all 12 factors. SA differed from both BDp and SZ in 9/12 factors: SA and BDp were similar in education and suicidal ideation or acts; SA and SZ were similar in education, onset stressors, and substance abuse. Meta-analytic comparisons of diagnostic pairs for 10 categorical factors indicated similar differences of SA from both SZ and BDp. Multivariate modeling indicated significantly independent differences between BDp and SZ (8 factors), SA vs. SZ (5), and BDp vs. SA (3). Measurement variance was similar for all diagnoses. Conclusion SA was consistently intermediate between BDp and SZ. The three diagnostic groups ranked: BDp > SA > SZ related to lesser morbidity or disability. The findings are not consistent with a dyadic Kraepelinian categorization, although the considerable overlap among the three DSM- IV diagnostic groups indicates uncertain boundaries if they represent distinct disorders. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 112334015 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Tondo%2C+L%2E%22">Tondo, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Vázquez%2C+G%2E+H%2E%22">Vázquez, G. H.</searchLink><br /><searchLink fieldCode="AR" term="%22Baethge%2C+C%2E%22">Baethge, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Baronessa%2C+C%2E%22">Baronessa, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Bolzani%2C+L%2E%22">Bolzani, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Koukopoulos%2C+A%2E%22">Koukopoulos, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Mazzarini%2C+L%2E%22">Mazzarini, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Murru%2C+A%2E%22">Murru, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Pacchiarotti%2C+I%2E%22">Pacchiarotti, I.</searchLink><br /><searchLink fieldCode="AR" term="%22Pinna%2C+M%2E%22">Pinna, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Salvatore%2C+P%2E%22">Salvatore, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Sani%2C+G%2E%22">Sani, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Selle%2C+V%2E%22">Selle, V.</searchLink><br /><searchLink fieldCode="AR" term="%22Spalletta%2C+G%2E%22">Spalletta, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Girardi%2C+P%2E%22">Girardi, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Tohen%2C+M%2E%22">Tohen, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Vieta%2C+E%2E%22">Vieta, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Baldessarini%2C+R%2E+J%2E%22">Baldessarini, R. J.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Jan2016, Vol. 133 Issue 1, p34-43. 10p. 5 Charts, 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Bipolar+disorder%22">Bipolar disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Schizophrenia%22">Schizophrenia</searchLink><br /><searchLink fieldCode="DE" term="%22Nosology%22">Nosology</searchLink><br /><searchLink fieldCode="DE" term="%22Sociodemographic+factors%22">Sociodemographic factors</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+ideation%22">Suicidal ideation</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objective Nosological distinctions among schizoaffective disorder ( SA), bipolar I disorder with psychotic features ( BDp), and schizophrenia ( SZ) remain unresolved. Method We compared 2269 subjects with psychotic features in DSM- IV- TR diagnoses (1435 BDp, 463 SZ, 371 SA) from 8 collaborating international sites, by 12 sociodemographic and clinical measures, all between diagnostic pairs. Results In bivariate comparisons, SA was consistently intermediate between BDp and SZ for 11/12 features (except onset stressors), and SZ vs. BDp differed in all 12 factors. SA differed from both BDp and SZ in 9/12 factors: SA and BDp were similar in education and suicidal ideation or acts; SA and SZ were similar in education, onset stressors, and substance abuse. Meta-analytic comparisons of diagnostic pairs for 10 categorical factors indicated similar differences of SA from both SZ and BDp. Multivariate modeling indicated significantly independent differences between BDp and SZ (8 factors), SA vs. SZ (5), and BDp vs. SA (3). Measurement variance was similar for all diagnoses. Conclusion SA was consistently intermediate between BDp and SZ. The three diagnostic groups ranked: BDp > SA > SZ related to lesser morbidity or disability. The findings are not consistent with a dyadic Kraepelinian categorization, although the considerable overlap among the three DSM- IV diagnostic groups indicates uncertain boundaries if they represent distinct disorders. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/acps.12447 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 34 Subjects: – SubjectFull: Bipolar disorder Type: general – SubjectFull: Schizophrenia Type: general – SubjectFull: Nosology Type: general – SubjectFull: Sociodemographic factors Type: general – SubjectFull: Suicidal ideation Type: general – SubjectFull: Multivariate analysis Type: general Titles: – TitleFull: Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tondo, L. – PersonEntity: Name: NameFull: Vázquez, G. H. – PersonEntity: Name: NameFull: Baethge, C. – PersonEntity: Name: NameFull: Baronessa, C. – PersonEntity: Name: NameFull: Bolzani, L. – PersonEntity: Name: NameFull: Koukopoulos, A. – PersonEntity: Name: NameFull: Mazzarini, L. – PersonEntity: Name: NameFull: Murru, A. – PersonEntity: Name: NameFull: Pacchiarotti, I. – PersonEntity: Name: NameFull: Pinna, M. – PersonEntity: Name: NameFull: Salvatore, P. – PersonEntity: Name: NameFull: Sani, G. – PersonEntity: Name: NameFull: Selle, V. – PersonEntity: Name: NameFull: Spalletta, G. – PersonEntity: Name: NameFull: Girardi, P. – PersonEntity: Name: NameFull: Tohen, M. – PersonEntity: Name: NameFull: Vieta, E. – PersonEntity: Name: NameFull: Baldessarini, R. J. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2016 Type: published Y: 2016 Identifiers: – Type: issn-print Value: 0001690X Numbering: – Type: volume Value: 133 – Type: issue Value: 1 Titles: – TitleFull: Acta Psychiatrica Scandinavica Type: main |
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