Legionnaires' disease.

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Bibliographic Details
Title: Legionnaires' disease.
Authors: Cunha, Burke A., Burillo, Almudena, Bouza, Emilio
Source: Lancet. 1/23/2016, Vol. 387 Issue 10016, p376-385. 10p.
Subjects: Legionella, Legionnaires' disease, Immunosuppression, Pneumonia, Microbiology, Legionnaires' disease diagnosis, Antibiotics, Bacteriology technique, Infectious disease transmission, Cultures (Biology), Epidemics, Public health, Water supply, Disease incidence, Pharmacodynamics, Therapeutics
Abstract: Since first identified in early 1977, bacteria of the genus Legionella are recognised as a common cause of community-acquired pneumonia and a rare cause of hospital-acquired pneumonia. Legionella bacteria multisystem manifestations mainly affect susceptible patients as a result of age, underlying debilitating conditions, or immunosuppression. Water is the major natural reservoir for Legionella, and the pathogen is found in many different natural and artificial aquatic environments such as cooling towers or water systems in buildings, including hospitals. The term given to the severe pneumonia and systemic infection caused by Legionella bacteria is Legionnaires' disease. Over time, the prevalence of legionellosis or Legionnaires' disease has risen, which might indicate a greater awareness and reporting of the disease. Advances in microbiology have led to a better understanding of the ecological niches and pathogenesis of the condition. Legionnaires' disease is not always suspected because of its non-specific symptoms, and the diagnostic tests routinely available do not offer the desired sensitivity. However, effective antibiotics are available. Disease notification systems provide the basis for initiating investigations and limiting the scale and recurrence of outbreaks. This report reviews our current understanding of this disease. [ABSTRACT FROM AUTHOR]
Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Since first identified in early 1977, bacteria of the genus Legionella are recognised as a common cause of community-acquired pneumonia and a rare cause of hospital-acquired pneumonia. Legionella bacteria multisystem manifestations mainly affect susceptible patients as a result of age, underlying debilitating conditions, or immunosuppression. Water is the major natural reservoir for Legionella, and the pathogen is found in many different natural and artificial aquatic environments such as cooling towers or water systems in buildings, including hospitals. The term given to the severe pneumonia and systemic infection caused by Legionella bacteria is Legionnaires' disease. Over time, the prevalence of legionellosis or Legionnaires' disease has risen, which might indicate a greater awareness and reporting of the disease. Advances in microbiology have led to a better understanding of the ecological niches and pathogenesis of the condition. Legionnaires' disease is not always suspected because of its non-specific symptoms, and the diagnostic tests routinely available do not offer the desired sensitivity. However, effective antibiotics are available. Disease notification systems provide the basis for initiating investigations and limiting the scale and recurrence of outbreaks. This report reviews our current understanding of this disease. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/S0140-6736(15)60078-2
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 10
        StartPage: 376
    Subjects:
      – SubjectFull: Legionella
        Type: general
      – SubjectFull: Legionnaires' disease
        Type: general
      – SubjectFull: Immunosuppression
        Type: general
      – SubjectFull: Pneumonia
        Type: general
      – SubjectFull: Microbiology
        Type: general
      – SubjectFull: Legionnaires' disease diagnosis
        Type: general
      – SubjectFull: Antibiotics
        Type: general
      – SubjectFull: Bacteriology technique
        Type: general
      – SubjectFull: Infectious disease transmission
        Type: general
      – SubjectFull: Cultures (Biology)
        Type: general
      – SubjectFull: Epidemics
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      – SubjectFull: Public health
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      – SubjectFull: Water supply
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      – SubjectFull: Disease incidence
        Type: general
      – SubjectFull: Pharmacodynamics
        Type: general
      – SubjectFull: Therapeutics
        Type: general
    Titles:
      – TitleFull: Legionnaires' disease.
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              Text: 1/23/2016
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