Bibliographic Details
| Title: |
The quality of life questionnaire for cancer patients treated with anticancer drugs (QOL-ACD): validity and reliability in japanese patients with advanced non-small-cell lung cancer. |
| Authors: |
Matsumoto, T., Ohashi, Y., Morita, S., Kobayashi, K., Shibuya, M., Yamaji, Y., Eguchi, K., Fukuoka, M., Nagao, K., Nishiwaki, Y., Niitani, H., CPT-11 Lung Cancer Study Groups West and East (CORPORATE AUTHOR) |
| Source: |
Quality of Life Research. Aug2002, Vol. 11 Issue 5, p483-493. 11p. |
| Subjects: |
Questionnaires, Quality of life, Small cell lung cancer, Patients |
| Abstract: |
The quality of life questionnaire for cancer patients treated with anticancer drugs (QOL-ACD), which consists of four domains (functional, physical, mental, and psychosocial) and a global face scale, was developed as a generic questionnaire for Japanese cancer patients undergoing chemotherapy. We examined the validity and reliability of this questionnaire in Japanese patients with advanced non-small-cell lung cancer (NSCLC), who participated in two randomized phase III trials. After excluding two items, one showing low test-retest reliability and the other showing poor convergent validity for the target population, Cronbach's alpha coefficients ranged from 0.795 to 0.897 and the intra-class correlation coefficients ranged from 0.612 to 0.866. These results confirmed the high reliability of the questionnaire. The results of factor analysis provided strong support for the domain structure used in the questionnaire. Each of the four domains had a moderate to strong association with important clinical variables, such as performance status or weight loss, and correlation analysis showed that the face scale provided an appropriate measure of the global quality of life. These results indicated that the QOL-ACD is potentially useful for clinical research on Japanese patients with advanced NSCLC. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
