View in EDS PDF Full Text

The influence of comorbid disorders on the episodicity of bipolar disorder in youth.

Saved in:
Bibliographic Details
Title: The influence of comorbid disorders on the episodicity of bipolar disorder in youth.
Authors: Yen, S., Stout, R., Hower, H., Killam, M. A., Weinstock, L. M., Topor, D. R., Dickstein, D. P., Hunt, J. I., Gill, M. K., Goldstein, T. R., Goldstein, B. I., Ryan, N. D., Strober, M., Sala, R., Axelson, D. A., Birmaher, B., Keller, M. B.
Source: Acta Psychiatrica Scandinavica. Apr2016, Vol. 133 Issue 4, p324-334. 11p. 4 Charts.
Subjects: Bipolar disorder in adolescence, Comorbidity, Pathological psychology, Anxiety disorders, Attention-deficit hyperactivity disorder
Abstract: Objective Bipolar disorder ( BP) frequently co-occurs with other psychiatric disorders. We examine whether course of anxiety disorders ( ANX), attention deficit hyperactivity disorder ( ADHD), disruptive behavior disorders ( DBD), and substance use disorders ( SUD) influence likelihood of recovery and recurrence of depression and mania in BP youth. Method Weekly ratings of psychiatric disorder intensity were obtained from 413 participants of the Course and Outcome of BP Youth project, followed for an average of 7.75 years. Multiple-event Cox proportional hazards regression analyses examined worsening of comorbid disorders as predictors of mood episode recovery and recurrence. Results Increased severity in ANX and SUD predicted longer time to recovery and less time to next depressive episode, and less time to next manic episode. Multivariate models with ANX and SUD found that significant effects of ANX remained, but SUD only predicted longer time to depression recovery. Increased severity of ADHD and DBD predicted shorter time to recurrence for depressive and manic episodes. Conclusion There are significant time-varying relationships between the course of comorbid disorders and episodicity of depression and mania in BP youth. Worsening of comorbid conditions may present as a precursor to mood episode recurrence or warn of mood episode protraction. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 113881334
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The influence of comorbid disorders on the episodicity of bipolar disorder in youth.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Yen%2C+S%2E%22">Yen, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Stout%2C+R%2E%22">Stout, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Hower%2C+H%2E%22">Hower, H.</searchLink><br /><searchLink fieldCode="AR" term="%22Killam%2C+M%2E+A%2E%22">Killam, M. A.</searchLink><br /><searchLink fieldCode="AR" term="%22Weinstock%2C+L%2E+M%2E%22">Weinstock, L. M.</searchLink><br /><searchLink fieldCode="AR" term="%22Topor%2C+D%2E+R%2E%22">Topor, D. R.</searchLink><br /><searchLink fieldCode="AR" term="%22Dickstein%2C+D%2E+P%2E%22">Dickstein, D. P.</searchLink><br /><searchLink fieldCode="AR" term="%22Hunt%2C+J%2E+I%2E%22">Hunt, J. I.</searchLink><br /><searchLink fieldCode="AR" term="%22Gill%2C+M%2E+K%2E%22">Gill, M. K.</searchLink><br /><searchLink fieldCode="AR" term="%22Goldstein%2C+T%2E+R%2E%22">Goldstein, T. R.</searchLink><br /><searchLink fieldCode="AR" term="%22Goldstein%2C+B%2E+I%2E%22">Goldstein, B. I.</searchLink><br /><searchLink fieldCode="AR" term="%22Ryan%2C+N%2E+D%2E%22">Ryan, N. D.</searchLink><br /><searchLink fieldCode="AR" term="%22Strober%2C+M%2E%22">Strober, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Sala%2C+R%2E%22">Sala, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Axelson%2C+D%2E+A%2E%22">Axelson, D. A.</searchLink><br /><searchLink fieldCode="AR" term="%22Birmaher%2C+B%2E%22">Birmaher, B.</searchLink><br /><searchLink fieldCode="AR" term="%22Keller%2C+M%2E+B%2E%22">Keller, M. B.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Apr2016, Vol. 133 Issue 4, p324-334. 11p. 4 Charts.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Bipolar+disorder+in+adolescence%22">Bipolar disorder in adolescence</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink><br /><searchLink fieldCode="DE" term="%22Pathological+psychology%22">Pathological psychology</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety+disorders%22">Anxiety disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Attention-deficit+hyperactivity+disorder%22">Attention-deficit hyperactivity disorder</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective Bipolar disorder ( BP) frequently co-occurs with other psychiatric disorders. We examine whether course of anxiety disorders ( ANX), attention deficit hyperactivity disorder ( ADHD), disruptive behavior disorders ( DBD), and substance use disorders ( SUD) influence likelihood of recovery and recurrence of depression and mania in BP youth. Method Weekly ratings of psychiatric disorder intensity were obtained from 413 participants of the Course and Outcome of BP Youth project, followed for an average of 7.75 years. Multiple-event Cox proportional hazards regression analyses examined worsening of comorbid disorders as predictors of mood episode recovery and recurrence. Results Increased severity in ANX and SUD predicted longer time to recovery and less time to next depressive episode, and less time to next manic episode. Multivariate models with ANX and SUD found that significant effects of ANX remained, but SUD only predicted longer time to depression recovery. Increased severity of ADHD and DBD predicted shorter time to recurrence for depressive and manic episodes. Conclusion There are significant time-varying relationships between the course of comorbid disorders and episodicity of depression and mania in BP youth. Worsening of comorbid conditions may present as a precursor to mood episode recurrence or warn of mood episode protraction. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=113881334
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/acps.12514
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 324
    Subjects:
      – SubjectFull: Bipolar disorder in adolescence
        Type: general
      – SubjectFull: Comorbidity
        Type: general
      – SubjectFull: Pathological psychology
        Type: general
      – SubjectFull: Anxiety disorders
        Type: general
      – SubjectFull: Attention-deficit hyperactivity disorder
        Type: general
    Titles:
      – TitleFull: The influence of comorbid disorders on the episodicity of bipolar disorder in youth.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Yen, S.
      – PersonEntity:
          Name:
            NameFull: Stout, R.
      – PersonEntity:
          Name:
            NameFull: Hower, H.
      – PersonEntity:
          Name:
            NameFull: Killam, M. A.
      – PersonEntity:
          Name:
            NameFull: Weinstock, L. M.
      – PersonEntity:
          Name:
            NameFull: Topor, D. R.
      – PersonEntity:
          Name:
            NameFull: Dickstein, D. P.
      – PersonEntity:
          Name:
            NameFull: Hunt, J. I.
      – PersonEntity:
          Name:
            NameFull: Gill, M. K.
      – PersonEntity:
          Name:
            NameFull: Goldstein, T. R.
      – PersonEntity:
          Name:
            NameFull: Goldstein, B. I.
      – PersonEntity:
          Name:
            NameFull: Ryan, N. D.
      – PersonEntity:
          Name:
            NameFull: Strober, M.
      – PersonEntity:
          Name:
            NameFull: Sala, R.
      – PersonEntity:
          Name:
            NameFull: Axelson, D. A.
      – PersonEntity:
          Name:
            NameFull: Birmaher, B.
      – PersonEntity:
          Name:
            NameFull: Keller, M. B.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: Apr2016
              Type: published
              Y: 2016
          Identifiers:
            – Type: issn-print
              Value: 0001690X
          Numbering:
            – Type: volume
              Value: 133
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Acta Psychiatrica Scandinavica
              Type: main
ResultId 1