Five year follow-up of non-psychotic adults with frequent auditory verbal hallucinations: are they still healthy?

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Title: Five year follow-up of non-psychotic adults with frequent auditory verbal hallucinations: are they still healthy?
Authors: Daalman, K., Diederen, K. M. J., Hoekema, L., van Lutterveld, R., Sommer, I. E. C.
Source: Psychological Medicine. Jul2016, Vol. 46 Issue 9, p1897-1907. 11p.
Subjects: Diagnosis of mental depression, Schizophrenia risk factors, Chi-squared test, Comparative studies, Auditory hallucinations, Intelligence tests, Interviewing, Longitudinal method, Medical needs assessment, Mental health services, Classification of mental disorders, Questionnaires, Telephones, Mathematical variables, Logistic regression analysis, Descriptive statistics, Mann Whitney U Test
Abstract: Background. Previously, we described 103 adults (mean age 41 years) who experienced frequent, auditory verbal hallucinations (AVH), in the absence of a need for mental healthcare. Importantly, these adults were largely past the peak incidence age for psychosis (15-35 years). It is unclear if these older individuals with AVH are still at increased risk for psychosis or other psychopathology. To address this question, we conducted a 5-year follow-up of previously included individuals (103 with AVH, 60 controls). Method. Eighty-one adults with AVH (78.6%) and forty-nine controls (81.7%) could be contacted and were willing to participate. Participants were screened for psychosis and a need for mental healthcare at follow-up using the Comprehensive Assessment of Symptoms and History interview (CASH). Need for mental healthcare was defined as a clinical diagnosis as identified using the CASH and/or treatment by a mental healthcare specialist. Phenomenology of AVH was assessed with the PSYRATS Auditory Hallucinations Rating Scale. Results. Five individuals with AVH (6.2%) had developed psychosis and 32 (39.5%) had developed a need for mental healthcare. Voice-related distress at baseline significantly predicted need for mental healthcare. AVH persisted in most individuals (86.4%), without significant changes in phenomenology. None of the controls had developed psychotic symptoms, and need for mental healthcare (n = 6, 12.2%) was significantly lower in this group. Conclusions. These findings suggest that frequentAVHin non-psychotic adults past the peak incidence age for psychosis constitute a rather static symptom and that individuals with AVH may be best viewed as situated on a need for care continuum. [ABSTRACT FROM AUTHOR]
Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Five year follow-up of non-psychotic adults with frequent auditory verbal hallucinations: are they still healthy?
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  Data: <searchLink fieldCode="AR" term="%22Daalman%2C+K%2E%22">Daalman, K.</searchLink><br /><searchLink fieldCode="AR" term="%22Diederen%2C+K%2E+M%2E+J%2E%22">Diederen, K. M. J.</searchLink><br /><searchLink fieldCode="AR" term="%22Hoekema%2C+L%2E%22">Hoekema, L.</searchLink><br /><searchLink fieldCode="AR" term="%22van+Lutterveld%2C+R%2E%22">van Lutterveld, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Sommer%2C+I%2E+E%2E+C%2E%22">Sommer, I. E. C.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Psychological+Medicine%22">Psychological Medicine</searchLink>. Jul2016, Vol. 46 Issue 9, p1897-1907. 11p.
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  Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+mental+depression%22">Diagnosis of mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Schizophrenia+risk+factors%22">Schizophrenia risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Chi-squared+test%22">Chi-squared test</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Auditory+hallucinations%22">Auditory hallucinations</searchLink><br /><searchLink fieldCode="DE" term="%22Intelligence+tests%22">Intelligence tests</searchLink><br /><searchLink fieldCode="DE" term="%22Interviewing%22">Interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+needs+assessment%22">Medical needs assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+health+services%22">Mental health services</searchLink><br /><searchLink fieldCode="DE" term="%22Classification+of+mental+disorders%22">Classification of mental disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Telephones%22">Telephones</searchLink><br /><searchLink fieldCode="DE" term="%22Mathematical+variables%22">Mathematical variables</searchLink><br /><searchLink fieldCode="DE" term="%22Logistic+regression+analysis%22">Logistic regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Mann+Whitney+U+Test%22">Mann Whitney U Test</searchLink>
– Name: Abstract
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  Data: Background. Previously, we described 103 adults (mean age 41 years) who experienced frequent, auditory verbal hallucinations (AVH), in the absence of a need for mental healthcare. Importantly, these adults were largely past the peak incidence age for psychosis (15-35 years). It is unclear if these older individuals with AVH are still at increased risk for psychosis or other psychopathology. To address this question, we conducted a 5-year follow-up of previously included individuals (103 with AVH, 60 controls). Method. Eighty-one adults with AVH (78.6%) and forty-nine controls (81.7%) could be contacted and were willing to participate. Participants were screened for psychosis and a need for mental healthcare at follow-up using the Comprehensive Assessment of Symptoms and History interview (CASH). Need for mental healthcare was defined as a clinical diagnosis as identified using the CASH and/or treatment by a mental healthcare specialist. Phenomenology of AVH was assessed with the PSYRATS Auditory Hallucinations Rating Scale. Results. Five individuals with AVH (6.2%) had developed psychosis and 32 (39.5%) had developed a need for mental healthcare. Voice-related distress at baseline significantly predicted need for mental healthcare. AVH persisted in most individuals (86.4%), without significant changes in phenomenology. None of the controls had developed psychotic symptoms, and need for mental healthcare (n = 6, 12.2%) was significantly lower in this group. Conclusions. These findings suggest that frequentAVHin non-psychotic adults past the peak incidence age for psychosis constitute a rather static symptom and that individuals with AVH may be best viewed as situated on a need for care continuum. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1017/S0033291716000386
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      – SubjectFull: Diagnosis of mental depression
        Type: general
      – SubjectFull: Schizophrenia risk factors
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      – SubjectFull: Chi-squared test
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