The pattern of ocular dominance columns in cat primary visual cortex: intra- and interindividual variability of column spacing and its dependence on genetic background.
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| Title: | The pattern of ocular dominance columns in cat primary visual cortex: intra- and interindividual variability of column spacing and its dependence on genetic background. |
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| Authors: | Kaschube, Matthias (AUTHOR), Wolf, Fred (AUTHOR), Puhlmann, Mathias (AUTHOR), Rathjen, Stefan (AUTHOR), Schmidt, Karl‐Friedrich (AUTHOR), Geisel, Theo (AUTHOR), Löwel, Siegrid (AUTHOR) |
| Source: | European Journal of Neuroscience. Dec2003, Vol. 18 Issue 12, p3251-3266. 16p. |
| Subjects: | Senses, Visual cortex, Cerebral cortex, Neurophysiology, Neurobiology, Neurosciences |
| Abstract: | We present a comprehensive analysis of the intrinsic variability of the periodicity of ocular dominance columns in cat primary visual cortex (area 17) and its relationship to genetic background and visual experience. We characterized the intra-areal and interindividual variability of column spacing in a large set ( n = 49) of ocular dominance patterns adapting a recently developed technique for the two-dimensional analysis of orientation column patterns. Patterns were obtained from three different cat colonies (termed F, M and D), the cats having either normal visual experience or experimentally induced strabismus. Two-dimensional maps of local column spacing were calculated for every pattern. In individual cortices, local column spacings varied by > 50% with the majority of column spacings ranging between 0.6 and 1.5 mm in different animals. In animals from colonies F and M ( n = 29), the mean column spacing ranged between 1.03 and 1.27 mm and exhibited no significant differences, either between the two breeds or between strabismic and normal animals. The mean spacing was moderately clustered in the left and right brain hemisphere of individual animals but not in littermates. In animals from colony D ( n = 2), average column spacing ranged between 0.73 and 0.95 mm, and was thus significantly different from the distribution of spacings in animals from breeds F and M, suggesting an influence of genetic factors on the layout of ocular dominance columns. Local column spacing exhibited a considerable systematic intra-areal variation, with largest spacings along the representation of the horizontal meridian and smallest spacings along the peripheral representation of the vertical meridian. The total variability of ocular dominance column spacing comprised 24% systematic intra-areal variation, 18% interindividual differences of mean column spacing and 58% nonsystematic intra-areal variability. [ABSTRACT FROM AUTHOR] |
| Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 11701957 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The pattern of ocular dominance columns in cat primary visual cortex: intra- and interindividual variability of column spacing and its dependence on genetic background. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Kaschube%2C+Matthias%22">Kaschube, Matthias</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wolf%2C+Fred%22">Wolf, Fred</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Puhlmann%2C+Mathias%22">Puhlmann, Mathias</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rathjen%2C+Stefan%22">Rathjen, Stefan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schmidt%2C+Karl‐Friedrich%22">Schmidt, Karl‐Friedrich</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Geisel%2C+Theo%22">Geisel, Theo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Löwel%2C+Siegrid%22">Löwel, Siegrid</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neuroscience%22">European Journal of Neuroscience</searchLink>. Dec2003, Vol. 18 Issue 12, p3251-3266. 16p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Senses%22">Senses</searchLink><br /><searchLink fieldCode="DE" term="%22Visual+cortex%22">Visual cortex</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebral+cortex%22">Cerebral cortex</searchLink><br /><searchLink fieldCode="DE" term="%22Neurophysiology%22">Neurophysiology</searchLink><br /><searchLink fieldCode="DE" term="%22Neurobiology%22">Neurobiology</searchLink><br /><searchLink fieldCode="DE" term="%22Neurosciences%22">Neurosciences</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: We present a comprehensive analysis of the intrinsic variability of the periodicity of ocular dominance columns in cat primary visual cortex (area 17) and its relationship to genetic background and visual experience. We characterized the intra-areal and interindividual variability of column spacing in a large set ( n = 49) of ocular dominance patterns adapting a recently developed technique for the two-dimensional analysis of orientation column patterns. Patterns were obtained from three different cat colonies (termed F, M and D), the cats having either normal visual experience or experimentally induced strabismus. Two-dimensional maps of local column spacing were calculated for every pattern. In individual cortices, local column spacings varied by > 50% with the majority of column spacings ranging between 0.6 and 1.5 mm in different animals. In animals from colonies F and M ( n = 29), the mean column spacing ranged between 1.03 and 1.27 mm and exhibited no significant differences, either between the two breeds or between strabismic and normal animals. The mean spacing was moderately clustered in the left and right brain hemisphere of individual animals but not in littermates. In animals from colony D ( n = 2), average column spacing ranged between 0.73 and 0.95 mm, and was thus significantly different from the distribution of spacings in animals from breeds F and M, suggesting an influence of genetic factors on the layout of ocular dominance columns. Local column spacing exhibited a considerable systematic intra-areal variation, with largest spacings along the representation of the horizontal meridian and smallest spacings along the peripheral representation of the vertical meridian. The total variability of ocular dominance column spacing comprised 24% systematic intra-areal variation, 18% interindividual differences of mean column spacing and 58% nonsystematic intra-areal variability. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/j.1460-9568.2003.02979.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 16 StartPage: 3251 Subjects: – SubjectFull: Senses Type: general – SubjectFull: Visual cortex Type: general – SubjectFull: Cerebral cortex Type: general – SubjectFull: Neurophysiology Type: general – SubjectFull: Neurobiology Type: general – SubjectFull: Neurosciences Type: general Titles: – TitleFull: The pattern of ocular dominance columns in cat primary visual cortex: intra- and interindividual variability of column spacing and its dependence on genetic background. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kaschube, Matthias – PersonEntity: Name: NameFull: Wolf, Fred – PersonEntity: Name: NameFull: Puhlmann, Mathias – PersonEntity: Name: NameFull: Rathjen, Stefan – PersonEntity: Name: NameFull: Schmidt, Karl‐Friedrich – PersonEntity: Name: NameFull: Geisel, Theo – PersonEntity: Name: NameFull: Löwel, Siegrid IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 12 Text: Dec2003 Type: published Y: 2003 Identifiers: – Type: issn-print Value: 0953816X Numbering: – Type: volume Value: 18 – Type: issue Value: 12 Titles: – TitleFull: European Journal of Neuroscience Type: main |
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