Meta-analysis of erythrocyte Na,K-ATPase activity in bipolar illness This work was presented at the Second Great Lakes Symposium on Medical Statistics, Kalamazoo, MI, October 6–8, 1993, and at the 1995 Spring Meeting of the Eastern North American Region of the International Biometric Society, Birmingham, AL, March 26–29, 1995

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Title: Meta-analysis of erythrocyte Na,K-ATPase activity in bipolar illness This work was presented at the Second Great Lakes Symposium on Medical Statistics, Kalamazoo, MI, October 6–8, 1993, and at the 1995 Spring Meeting of the Eastern North American Region of the International Biometric Society, Birmingham, AL, March 26–29, 1995
Authors: Looney, Stephen W., El-Mallakh, Rif S., Looney, S W (AUTHOR), el-Mallakh, R S (AUTHOR)
Source: Depression & Anxiety (1091-4269). 1997, Vol. 5 Issue 2, p53-65. 13p. 2 Charts, 6 Graphs.
Subjects: Affective disorders, Erythrocytes, Meta-analysis, Adenosine triphosphatase, Mental depression
Abstract: Sodium, potassium-activated adenosine triphosphatase (Na,K-ATPase) pump activity has been variously reported to be increased, decreased, or unchanged in bipolar patients. To explore this association we conducted a meta-analysis of the available literature. All papers containing data on erythrocyte Na,K-ATPase activity were reviewed independently by both authors. A meta-analysis of these data was accomplished by standard procedure. We found a significant mood-state-related decrease in Na,K-ATPase activity in both manic and bipolar depressed patients when compared to euthymic bipolar patients, but not when ill patients were compared to normal controls. The overall change can be characterized as small to moderate in magnitude. [ABSTRACT FROM AUTHOR]
Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Meta-analysis of erythrocyte Na,K-ATPase activity in bipolar illness <FNR></FNR><FN>This work was presented at the Second Great Lakes Symposium on Medical Statistics, Kalamazoo, MI, October 6–8, 1993, and at the 1995 Spring Meeting of the Eastern North American Region of the International Biometric Society, Birmingham, AL, March 26–29, 1995 </FN>
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  Data: <searchLink fieldCode="AR" term="%22Looney%2C+Stephen+W%2E%22">Looney, Stephen W.</searchLink><br /><searchLink fieldCode="AR" term="%22El-Mallakh%2C+Rif+S%2E%22">El-Mallakh, Rif S.</searchLink><br /><searchLink fieldCode="AR" term="%22Looney%2C+S+W%22">Looney, S W</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22el-Mallakh%2C+R+S%22">el-Mallakh, R S</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Depression+%26+Anxiety+%281091-4269%29%22">Depression & Anxiety (1091-4269)</searchLink>. 1997, Vol. 5 Issue 2, p53-65. 13p. 2 Charts, 6 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Affective+disorders%22">Affective disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Erythrocytes%22">Erythrocytes</searchLink><br /><searchLink fieldCode="DE" term="%22Meta-analysis%22">Meta-analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Adenosine+triphosphatase%22">Adenosine triphosphatase</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink>
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  Data: Sodium, potassium-activated adenosine triphosphatase (Na,K-ATPase) pump activity has been variously reported to be increased, decreased, or unchanged in bipolar patients. To explore this association we conducted a meta-analysis of the available literature. All papers containing data on erythrocyte Na,K-ATPase activity were reviewed independently by both authors. A meta-analysis of these data was accomplished by standard procedure. We found a significant mood-state-related decrease in Na,K-ATPase activity in both manic and bipolar depressed patients when compared to euthymic bipolar patients, but not when ill patients were compared to normal controls. The overall change can be characterized as small to moderate in magnitude. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/(SICI)1520-6394(1997)5:2<53::AID-DA1>3.0.CO;2-6
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      – Code: eng
        Text: English
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        PageCount: 13
        StartPage: 53
    Subjects:
      – SubjectFull: Affective disorders
        Type: general
      – SubjectFull: Erythrocytes
        Type: general
      – SubjectFull: Meta-analysis
        Type: general
      – SubjectFull: Adenosine triphosphatase
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      – SubjectFull: Mental depression
        Type: general
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      – TitleFull: Meta-analysis of erythrocyte Na,K-ATPase activity in bipolar illness <FNR></FNR><FN>This work was presented at the Second Great Lakes Symposium on Medical Statistics, Kalamazoo, MI, October 6–8, 1993, and at the 1995 Spring Meeting of the Eastern North American Region of the International Biometric Society, Birmingham, AL, March 26–29, 1995 </FN>
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              Text: 1997
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