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Risk of mortality for dementia in a developing country: the Yoruba in Nigeria.

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Title: Risk of mortality for dementia in a developing country: the Yoruba in Nigeria.
Authors: Perkins, Anthony J., Siu L. Hui, Ogunniyi, Adesola, Gureje, Oyewusi, Baiyewu, Olusegun, Unverzagt, Frederick W., Gao, Sujuan, Hall, Kathleen S., Musick, Beverly S., Hendrie, Hugh C.
Source: International Journal of Geriatric Psychiatry. Jun2002, Vol. 17 Issue 6, p566-573. 8p. 4 Charts, 1 Graph.
Subjects: Dementia, Alzheimer's disease, Causes of death, Developing countries
Geographic Terms: Sub-Saharan Africa
Abstract: Background Limited data exist on the impact of dementia in developing nations, including its association with mortality. Objective The purpose of this paper is to assess the relationship between dementia and five-year mortality on a community dwelling elderly Yoruba population in the developing country of Nigeria and to compare those results with those from an elderly African–American community in Indianapolis. Methods A two-phase design was used to ascertain dementia status in two sites. In the first phase, the Community Screening Instrument for Dementia (CSI-D) was administered. In the second phase, subjects were sampled for the clinical assessment according to their CSI-D performance category. Proportional hazards regression was used to assess the relationship between mortality and cognitive status at both sites after adjusting for demographics and chronic disease conditions. Results For the entire screened population, poor and intermediate performance on the CSI-D is associated with increased mortality at both sites; however the effect of CSI-D performance did not significantly differ between the two sites. For the clinically assessed sample, dementia was significantly associated with increased mortality at both sites (Ibadan RR = 2.83, Indianapolis RR = 2.05), but the effect was not significantly different across the two sites. Conclusion Dementia resulted in an increased risk of mortality for Yoruba of a magnitude similar to African–Americans suggesting that the impact of dementia on mortality risk may be similar for developing and developed countries. Copyright © 2002 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Geriatric Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Risk of mortality for dementia in a developing country: the Yoruba in Nigeria.
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  Data: <searchLink fieldCode="AR" term="%22Perkins%2C+Anthony+J%2E%22">Perkins, Anthony J.</searchLink><br /><searchLink fieldCode="AR" term="%22Siu+L%2E+Hui%22">Siu L. Hui</searchLink><br /><searchLink fieldCode="AR" term="%22Ogunniyi%2C+Adesola%22">Ogunniyi, Adesola</searchLink><br /><searchLink fieldCode="AR" term="%22Gureje%2C+Oyewusi%22">Gureje, Oyewusi</searchLink><br /><searchLink fieldCode="AR" term="%22Baiyewu%2C+Olusegun%22">Baiyewu, Olusegun</searchLink><br /><searchLink fieldCode="AR" term="%22Unverzagt%2C+Frederick+W%2E%22">Unverzagt, Frederick W.</searchLink><br /><searchLink fieldCode="AR" term="%22Gao%2C+Sujuan%22">Gao, Sujuan</searchLink><br /><searchLink fieldCode="AR" term="%22Hall%2C+Kathleen+S%2E%22">Hall, Kathleen S.</searchLink><br /><searchLink fieldCode="AR" term="%22Musick%2C+Beverly+S%2E%22">Musick, Beverly S.</searchLink><br /><searchLink fieldCode="AR" term="%22Hendrie%2C+Hugh+C%2E%22">Hendrie, Hugh C.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Geriatric+Psychiatry%22">International Journal of Geriatric Psychiatry</searchLink>. Jun2002, Vol. 17 Issue 6, p566-573. 8p. 4 Charts, 1 Graph.
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  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22Dementia%22">Dementia</searchLink><br /><searchLink fieldCode="DE" term="%22Alzheimer's+disease%22">Alzheimer's disease</searchLink><br /><searchLink fieldCode="DE" term="%22Causes+of+death%22">Causes of death</searchLink><br /><searchLink fieldCode="DE" term="%22Developing+countries%22">Developing countries</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Sub-Saharan+Africa%22">Sub-Saharan Africa</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background Limited data exist on the impact of dementia in developing nations, including its association with mortality. Objective The purpose of this paper is to assess the relationship between dementia and five-year mortality on a community dwelling elderly Yoruba population in the developing country of Nigeria and to compare those results with those from an elderly African–American community in Indianapolis. Methods A two-phase design was used to ascertain dementia status in two sites. In the first phase, the Community Screening Instrument for Dementia (CSI-D) was administered. In the second phase, subjects were sampled for the clinical assessment according to their CSI-D performance category. Proportional hazards regression was used to assess the relationship between mortality and cognitive status at both sites after adjusting for demographics and chronic disease conditions. Results For the entire screened population, poor and intermediate performance on the CSI-D is associated with increased mortality at both sites; however the effect of CSI-D performance did not significantly differ between the two sites. For the clinically assessed sample, dementia was significantly associated with increased mortality at both sites (Ibadan RR = 2.83, Indianapolis RR = 2.05), but the effect was not significantly different across the two sites. Conclusion Dementia resulted in an increased risk of mortality for Yoruba of a magnitude similar to African–Americans suggesting that the impact of dementia on mortality risk may be similar for developing and developed countries. Copyright © 2002 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of International Journal of Geriatric Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Jun2002
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