Melatonin sensitivity to dim white light in different seasons.
Saved in:
| Title: | Melatonin sensitivity to dim white light in different seasons. |
|---|---|
| Authors: | Nathan, Pradeep J., Burrows, Graham D., Norman, Trevor R. |
| Source: | Human Psychopharmacology: Clinical & Experimental. Jan99, Vol. 14 Issue 1, p53-58. 6p. 1 Chart, 2 Graphs. |
| Subjects: | Melatonin, Pineal gland secretions, Hormones, Affective disorders, Physiological effects of light |
| Abstract: | It is well known that the pineal hormone melatonin is suppressed by light. The melatonin suppression by dim light has also been suggested as a possible trait marker of bipolar disorder. However, there is large inter individual differences in the light responses. It is possible that methodological factors may contribute to the variable responses observed. Most studies in the past have been conducted in different seasons under different lighting conditions. It is possible the external lighting conditions may affect the melatonin suppression to dim light. Hence we examined the melatonin suppression by dim light in (1) a large group of subjects randomly tested once in one of the four seasons (part one) and (2) small group of subjects tested in all seasons (part two). Subjects were placed in a dark room from 2100 h to 0230 h. Light exposure was between midnight and 0100 h in a sitting position. Blood samples were collected at regular intervals for measurement of plasma melatonin. No statistically significant seasonal differences in the percentage suppression of melatonin were found in both parts of the study (p >0·5). The study suggests that seasonal changes in external lighting do not affect the melatonin suppression by dim light in healthy controls. Copyright © 1999 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR] |
| Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 11822141 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Melatonin sensitivity to dim white light in different seasons. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Nathan%2C+Pradeep+J%2E%22">Nathan, Pradeep J.</searchLink><br /><searchLink fieldCode="AR" term="%22Burrows%2C+Graham+D%2E%22">Burrows, Graham D.</searchLink><br /><searchLink fieldCode="AR" term="%22Norman%2C+Trevor+R%2E%22">Norman, Trevor R.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Human+Psychopharmacology%3A+Clinical+%26+Experimental%22">Human Psychopharmacology: Clinical & Experimental</searchLink>. Jan99, Vol. 14 Issue 1, p53-58. 6p. 1 Chart, 2 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Melatonin%22">Melatonin</searchLink><br /><searchLink fieldCode="DE" term="%22Pineal+gland+secretions%22">Pineal gland secretions</searchLink><br /><searchLink fieldCode="DE" term="%22Hormones%22">Hormones</searchLink><br /><searchLink fieldCode="DE" term="%22Affective+disorders%22">Affective disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Physiological+effects+of+light%22">Physiological effects of light</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: It is well known that the pineal hormone melatonin is suppressed by light. The melatonin suppression by dim light has also been suggested as a possible trait marker of bipolar disorder. However, there is large inter individual differences in the light responses. It is possible that methodological factors may contribute to the variable responses observed. Most studies in the past have been conducted in different seasons under different lighting conditions. It is possible the external lighting conditions may affect the melatonin suppression to dim light. Hence we examined the melatonin suppression by dim light in (1) a large group of subjects randomly tested once in one of the four seasons (part one) and (2) small group of subjects tested in all seasons (part two). Subjects were placed in a dark room from 2100 h to 0230 h. Light exposure was between midnight and 0100 h in a sitting position. Blood samples were collected at regular intervals for measurement of plasma melatonin. No statistically significant seasonal differences in the percentage suppression of melatonin were found in both parts of the study (p >0·5). The study suggests that seasonal changes in external lighting do not affect the melatonin suppression by dim light in healthy controls. Copyright © 1999 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=11822141 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/(SICI)1099-1077(199901)14:1<53::AID-HUP69>3.0.CO;2-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 53 Subjects: – SubjectFull: Melatonin Type: general – SubjectFull: Pineal gland secretions Type: general – SubjectFull: Hormones Type: general – SubjectFull: Affective disorders Type: general – SubjectFull: Physiological effects of light Type: general Titles: – TitleFull: Melatonin sensitivity to dim white light in different seasons. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Nathan, Pradeep J. – PersonEntity: Name: NameFull: Burrows, Graham D. – PersonEntity: Name: NameFull: Norman, Trevor R. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan99 Type: published Y: 1999 Identifiers: – Type: issn-print Value: 08856222 Numbering: – Type: volume Value: 14 – Type: issue Value: 1 Titles: – TitleFull: Human Psychopharmacology: Clinical & Experimental Type: main |
| ResultId | 1 |
