The spatial structure of correlated neuronal variability.
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| Title: | The spatial structure of correlated neuronal variability. |
|---|---|
| Authors: | Rosenbaum, Robert, Smith, Matthew A, Kohn, Adam, Rubin, Jonathan E, Doiron, Brent |
| Source: | Nature Neuroscience. Jan2017, Vol. 20 Issue 1, p107-114. 8p. 1 Diagram, 6 Graphs. |
| Abstract: | Shared neural variability is ubiquitous in cortical populations. While this variability is presumed to arise from overlapping synaptic input, its precise relationship to local circuit architecture remains unclear. We combine computational models and in vivo recordings to study the relationship between the spatial structure of connectivity and correlated variability in neural circuits. Extending the theory of networks with balanced excitation and inhibition, we find that spatially localized lateral projections promote weakly correlated spiking, but broader lateral projections produce a distinctive spatial correlation structure: nearby neuron pairs are positively correlated, pairs at intermediate distances are negatively correlated and distant pairs are weakly correlated. This non-monotonic dependence of correlation on distance is revealed in a new analysis of recordings from superficial layers of macaque primary visual cortex. Our findings show that incorporating distance-dependent connectivity improves the extent to which balanced network theory can explain correlated neural variability. [ABSTRACT FROM AUTHOR] |
| Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 120393066 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/nn.4433 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 107 Titles: – TitleFull: The spatial structure of correlated neuronal variability. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Rosenbaum, Robert – PersonEntity: Name: NameFull: Smith, Matthew A – PersonEntity: Name: NameFull: Kohn, Adam – PersonEntity: Name: NameFull: Rubin, Jonathan E – PersonEntity: Name: NameFull: Doiron, Brent IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2017 Type: published Y: 2017 Identifiers: – Type: issn-print Value: 10976256 Numbering: – Type: volume Value: 20 – Type: issue Value: 1 Titles: – TitleFull: Nature Neuroscience Type: main |
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