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Validation of a New Arabic Version of the Neuropathic Pain Diagnostic Questionnaire (DN4).

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Title: Validation of a New Arabic Version of the Neuropathic Pain Diagnostic Questionnaire (DN4).
Authors: Chatila, Nadwa, Pereira, Bruno, Maarrawi, Joseph, Dallel, Radhouane
Source: Pain Practice. Jan2017, Vol. 17 Issue 1, p78-87. 10p. 1 Diagram, 9 Charts, 2 Graphs.
Subjects: Peripheral neuropathy diagnosis, Chi-squared test, Confidence intervals, Education, Informed consent (Medical law), Language & languages, Research methodology, Medical protocols, Psychometrics, Questionnaires, Research funding, Semantics, Transcultural medical care, Translations, Patient selection, Receiver operating characteristic curves, Data analysis software, Mann Whitney U Test
Geographic Terms: Arabian Peninsula, Lebanon
Abstract: The 'Douleur Neuropathique 4 ( DN4) questionnaire' was developed for screening neuropathic pain. The purpose of this work was to validate the DN4 questionnaire in the standard Arabic language. First, the questionnaire was translated and semantically adapted to Arabic according to the international guidelines for cross-cultural adaptation. Second, a prospective observational study was performed to validate this questionnaire. A total of 195 patients with chronic pain ( n = 99 with neuropathic pain and n = 96 without neuropathic pain) were enrolled in the study. The internal consistency Kuder-Richardson's Formula 20 for the whole DN4 questionnaire was 0.86 ( P < 0.001) and the intraclass correlation coefficient 0.99 (95% CI: 0.99 to 1.00). The test-retest reliability kappa coefficient for each item ranged from 0.92 to 1.00. Using a receiver-operating characteristic ( ROC) curve analysis, the areas under the curve were 0.94 and 0.97 for the 7-item DN4 and 10-item DN4, respectively. A cut-off score of 3 resulted in a sensitivity of 97.0% and a specificity of 82.3% for the 7-item DN4, while a cut-off score of 5 for the 10-item DN4 resulted in a sensitivity of 93.0% and a specificity of 95.8%. Tingling, numbness, and hypoesthesia to touch and to pricking were the most discriminating pain items. The sensitivity and specificity of the 7-item DN4 and 10-item DN4 were not influenced by either pain severity or educational level. In conclusion, this new Arabic version DN4 questionnaire is a simple, reliable, and valid tool for discriminating between neuropathic and non-neuropathic pain. It represents a useful tool in clinical setting and population-based studies. [ABSTRACT FROM AUTHOR]
Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Validation of a New Arabic Version of the Neuropathic Pain Diagnostic Questionnaire (DN4).
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Pain+Practice%22&quot;&gt;Pain Practice&lt;/searchLink&gt;. Jan2017, Vol. 17 Issue 1, p78-87. 10p. 1 Diagram, 9 Charts, 2 Graphs.
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  Data: The &#39;Douleur Neuropathique 4 ( DN4) questionnaire&#39; was developed for screening neuropathic pain. The purpose of this work was to validate the DN4 questionnaire in the standard Arabic language. First, the questionnaire was translated and semantically adapted to Arabic according to the international guidelines for cross-cultural adaptation. Second, a prospective observational study was performed to validate this questionnaire. A total of 195 patients with chronic pain ( n = 99 with neuropathic pain and n = 96 without neuropathic pain) were enrolled in the study. The internal consistency Kuder-Richardson&#39;s Formula 20 for the whole DN4 questionnaire was 0.86 ( P &lt; 0.001) and the intraclass correlation coefficient 0.99 (95% CI: 0.99 to 1.00). The test-retest reliability kappa coefficient for each item ranged from 0.92 to 1.00. Using a receiver-operating characteristic ( ROC) curve analysis, the areas under the curve were 0.94 and 0.97 for the 7-item DN4 and 10-item DN4, respectively. A cut-off score of 3 resulted in a sensitivity of 97.0% and a specificity of 82.3% for the 7-item DN4, while a cut-off score of 5 for the 10-item DN4 resulted in a sensitivity of 93.0% and a specificity of 95.8%. Tingling, numbness, and hypoesthesia to touch and to pricking were the most discriminating pain items. The sensitivity and specificity of the 7-item DN4 and 10-item DN4 were not influenced by either pain severity or educational level. In conclusion, this new Arabic version DN4 questionnaire is a simple, reliable, and valid tool for discriminating between neuropathic and non-neuropathic pain. It represents a useful tool in clinical setting and population-based studies. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=120786277
RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1111/papr.12419
    Languages:
      – Code: eng
        Text: English
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      Pagination:
        PageCount: 10
        StartPage: 78
    Subjects:
      – SubjectFull: Peripheral neuropathy diagnosis
        Type: general
      – SubjectFull: Chi-squared test
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Education
        Type: general
      – SubjectFull: Informed consent (Medical law)
        Type: general
      – SubjectFull: Language & languages
        Type: general
      – SubjectFull: Research methodology
        Type: general
      – SubjectFull: Medical protocols
        Type: general
      – SubjectFull: Psychometrics
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Research funding
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      – SubjectFull: Semantics
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      – SubjectFull: Transcultural medical care
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      – SubjectFull: Translations
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      – SubjectFull: Patient selection
        Type: general
      – SubjectFull: Receiver operating characteristic curves
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Mann Whitney U Test
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      – SubjectFull: Arabian Peninsula
        Type: general
      – SubjectFull: Lebanon
        Type: general
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      – TitleFull: Validation of a New Arabic Version of the Neuropathic Pain Diagnostic Questionnaire (DN4).
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            NameFull: Chatila, Nadwa
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            NameFull: Pereira, Bruno
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              Text: Jan2017
              Type: published
              Y: 2017
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