The Association Between Social Support, Body Mass Index and Increased Risk of Prediabetes: the Cardiovascular Risk in Young Finns Study.

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Title: The Association Between Social Support, Body Mass Index and Increased Risk of Prediabetes: the Cardiovascular Risk in Young Finns Study.
Authors: Serlachius, Anna, Elovainio, Marko, Juonala, Markus, Shea, Steven, Sabin, Matthew, Lehtimäki, Terho, Raitakari, Olli, Keltikangas-Järvinen, Liisa, Pulkki-Råback, Laura
Source: International Journal of Behavioral Medicine. Apr2017, Vol. 24 Issue 2, p161-170. 10p.
Subjects: Type 2 diabetes risk factors, Prediabetic state, C-reactive protein, Cardiovascular diseases risk factors, Confidence intervals, Mental depression, Fasting, Glucose, Inflammation, Longitudinal method, Health outcome assessment, Probability theory, Regression analysis, Research funding, Sex distribution, Logistic regression analysis, Social support, Socioeconomic factors, Body mass index, Data analysis software, Descriptive statistics, Odds ratio, Disease risk factors
Geographic Terms: Finland
Abstract: Purpose: The psychosocial determinants of prediabetes are poorly understood. The aims of our study were (1) to analyse the association between perceived social support in young adulthood and fasting glucose levels and prediabetes in mid-adulthood in a cohort of healthy Finns, (2) to explore whether body mass index (BMI), inflammation or depression mediate this relationship, (3) and to examine the association between social support trajectory groups and fasting glucose. Method: A prospective design was used with an analytic sample of 1250 participants aged 3-18 years at baseline (1980) and aged 12-39 years when social support was measured. Fasting glucose and prediabetes were assessed 32 years after baseline. Linear and logistic regression was used to examine the association between social support and the outcome measures. A bootstrapping technique was used to examine mediation effects. Results: Social support was associated with future glucose levels in women after adjusting for childhood socioeconomic status (SES) and youth depression ( β = −0.136, p = 0.001) and also predicted prediabetes in women after adjusting for childhood SES ( β = 1.31, 95 % CI 1.02 to 1.69, p = 0.031). Both associations were attenuated after adjusting for BMI in mid-adulthood. BMI was found to mediate the relationship between social support and prediabetes in women ( β for indirect effect β = 0.09, SE = 0.03, CI = 0.03 to 0.16). Conclusion: Low perceived social support in young adulthood is associated with high fasting glucose and prediabetes in mid-adulthood in women but not men. The association between social support and prediabetes in women can be partly explained by BMI. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Behavioral Medicine is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: The Association Between Social Support, Body Mass Index and Increased Risk of Prediabetes: the Cardiovascular Risk in Young Finns Study.
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– Name: Abstract
  Label: Abstract
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  Data: Purpose: The psychosocial determinants of prediabetes are poorly understood. The aims of our study were (1) to analyse the association between perceived social support in young adulthood and fasting glucose levels and prediabetes in mid-adulthood in a cohort of healthy Finns, (2) to explore whether body mass index (BMI), inflammation or depression mediate this relationship, (3) and to examine the association between social support trajectory groups and fasting glucose. Method: A prospective design was used with an analytic sample of 1250 participants aged 3-18 years at baseline (1980) and aged 12-39 years when social support was measured. Fasting glucose and prediabetes were assessed 32 years after baseline. Linear and logistic regression was used to examine the association between social support and the outcome measures. A bootstrapping technique was used to examine mediation effects. Results: Social support was associated with future glucose levels in women after adjusting for childhood socioeconomic status (SES) and youth depression ( β = −0.136, p = 0.001) and also predicted prediabetes in women after adjusting for childhood SES ( β = 1.31, 95 % CI 1.02 to 1.69, p = 0.031). Both associations were attenuated after adjusting for BMI in mid-adulthood. BMI was found to mediate the relationship between social support and prediabetes in women ( β for indirect effect β = 0.09, SE = 0.03, CI = 0.03 to 0.16). Conclusion: Low perceived social support in young adulthood is associated with high fasting glucose and prediabetes in mid-adulthood in women but not men. The association between social support and prediabetes in women can be partly explained by BMI. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of International Journal of Behavioral Medicine is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1007/s12529-016-9597-0
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        Text: English
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      – SubjectFull: Type 2 diabetes risk factors
        Type: general
      – SubjectFull: Prediabetic state
        Type: general
      – SubjectFull: C-reactive protein
        Type: general
      – SubjectFull: Cardiovascular diseases risk factors
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Mental depression
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      – SubjectFull: Fasting
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      – SubjectFull: Glucose
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      – SubjectFull: Inflammation
        Type: general
      – SubjectFull: Longitudinal method
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      – SubjectFull: Health outcome assessment
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      – SubjectFull: Probability theory
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      – SubjectFull: Regression analysis
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      – SubjectFull: Research funding
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      – SubjectFull: Sex distribution
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      – SubjectFull: Logistic regression analysis
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      – SubjectFull: Social support
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      – SubjectFull: Finland
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