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Mobile assessment of heightened skin conductance in posttraumatic stress disorder.

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Title: Mobile assessment of heightened skin conductance in posttraumatic stress disorder.
Authors: Hinrichs, Rebecca, Michopoulos, Vasiliki, Winters, Sterling, Rothbaum, Alex O., Rothbaum, Barbara O., Ressler, Kerry J., Jovanovic, Tanja
Source: Depression & Anxiety (1091-4269). Jun2017, Vol. 34 Issue 6, p502-507. 6p. 1 Color Photograph, 1 Chart, 1 Graph.
Subjects: Galvanic skin response, Post-traumatic stress disorder, Psychophysiology, Logistic regression analysis, Mobile app development, Patient monitoring equipment, Diagnosis of post-traumatic stress disorder, Mental status examination, Patient monitoring, Research funding, Skin physiology, Pilot projects, Mobile apps
Abstract: Background: Increased psychophysiological reactivity is a hallmark intermediate phenotype of posttraumatic stress disorder (PTSD). Individuals with PTSD exhibit greater skin conductance (SC) responses to trauma scripts than trauma survivors without PTSD. However, trauma scripts require time for development and cannot be easily used in a single visit. Thus, there is a need for a low-cost, easy-to-use, SC recording protocol for PTSD assessment.Methods: Using a mobile device (eSense) connected to a portable tablet computer, we assessed SC reactivity to a standard trauma interview (STI) in 63 participants recruited from Grady Memorial Hospital in Atlanta, GA, approximately 1 year after trauma exposure. SC response (SCR) was calculated by subtracting the SC level (SCL) at the end of the baseline recording from the maximum SCL during the STI.Results: SCL was significantly higher during the STI compared to baseline (P < .001), and individuals with PTSD showed significantly greater SCR than individuals without PTSD (P = .006). Logistic regression using SCR with PTSD diagnosis as the outcome showed an odds ratio of 1.76 (95% CI: 1.11-2.78). Lastly, higher SCR during the STI was also significantly associated with PTSD symptom total score controlling for demographics and trauma severity (b = 0.42, P = .001).Conclusions: The current study demonstrated feasibility of the use of a mobile device for assessing psychophysiological reactivity in those with PTSD. The use of this low-cost, easy-to-use mobile device to collect objective physiological data in concert with a STI can be easily disseminated in clinical and research settings. [ABSTRACT FROM AUTHOR]
Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Mobile assessment of heightened skin conductance in posttraumatic stress disorder.
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  Data: &lt;bold&gt;Background: &lt;/bold&gt;Increased psychophysiological reactivity is a hallmark intermediate phenotype of posttraumatic stress disorder (PTSD). Individuals with PTSD exhibit greater skin conductance (SC) responses to trauma scripts than trauma survivors without PTSD. However, trauma scripts require time for development and cannot be easily used in a single visit. Thus, there is a need for a low-cost, easy-to-use, SC recording protocol for PTSD assessment.&lt;bold&gt;Methods: &lt;/bold&gt;Using a mobile device (eSense) connected to a portable tablet computer, we assessed SC reactivity to a standard trauma interview (STI) in 63 participants recruited from Grady Memorial Hospital in Atlanta, GA, approximately 1 year after trauma exposure. SC response (SCR) was calculated by subtracting the SC level (SCL) at the end of the baseline recording from the maximum SCL during the STI.&lt;bold&gt;Results: &lt;/bold&gt;SCL was significantly higher during the STI compared to baseline (P &lt; .001), and individuals with PTSD showed significantly greater SCR than individuals without PTSD (P = .006). Logistic regression using SCR with PTSD diagnosis as the outcome showed an odds ratio of 1.76 (95% CI: 1.11-2.78). Lastly, higher SCR during the STI was also significantly associated with PTSD symptom total score controlling for demographics and trauma severity (b = 0.42, P = .001).&lt;bold&gt;Conclusions: &lt;/bold&gt;The current study demonstrated feasibility of the use of a mobile device for assessing psychophysiological reactivity in those with PTSD. The use of this low-cost, easy-to-use mobile device to collect objective physiological data in concert with a STI can be easily disseminated in clinical and research settings. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Depression &amp; Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1002/da.22610
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        Text: English
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      – SubjectFull: Galvanic skin response
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      – SubjectFull: Post-traumatic stress disorder
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      – SubjectFull: Psychophysiology
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      – SubjectFull: Logistic regression analysis
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      – SubjectFull: Mobile app development
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      – SubjectFull: Mental status examination
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      – SubjectFull: Research funding
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      – SubjectFull: Skin physiology
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      – TitleFull: Mobile assessment of heightened skin conductance in posttraumatic stress disorder.
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              Text: Jun2017
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