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Genie in a blotter: A comparative study of LSD and LSD analogues' effects and user profile.

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Title: Genie in a blotter: A comparative study of LSD and LSD analogues' effects and user profile.
Authors: Coney, Leigh D., Maier, Larissa J., Ferris, Jason A., Winstock, Adam R., Barratt, Monica J.
Source: Human Psychopharmacology: Clinical & Experimental. May2017, Vol. 32 Issue 3, pn/a-N.PAG. 6p.
Subjects: LSD (Drug), Drug side effects, Drug abusers, Pharmaceutical research, Hallucinogenic drugs
Abstract: Objective This study aimed to describe self-reported patterns of use and effects of lysergic acid diethylamide (LSD) analogues (AL-LAD, 1P-LSD, and ETH-LAD) and the characteristics of those who use them. Methods An anonymous self-selected online survey of people who use drugs (Global Drug Survey 2016; N = 96,894), which measured perceived drug effects of LSD and its analogues. Results Most LSD analogue users (91%) had also tried LSD. The proportion of U.K. and U.S. respondents reporting LSD analogue use in the last 12 months was higher than for LSD only. LSD analogue users described the effects as psychedelic (93%), over half (55%) obtained it online, and almost all (99%) reported an oral route of administration. The modal duration (8 hr) and time to peak (2 hr) of LSD analogues were not significantly different from LSD. Ratings for pleasurable high, strength of effect, comedown, urge to use more drugs, value for money, and risk of harm following use were significantly lower for LSD analogues compared with LSD. Conclusions LSD analogues were reported as similar in time to peak and duration as LSD but weaker in strength, pleasurable high, and comedown. Future studies should seek to replicate these findings with chemical confirmation and dose measurement. [ABSTRACT FROM AUTHOR]
Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Genie in a blotter: A comparative study of LSD and LSD analogues' effects and user profile.
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  Data: <searchLink fieldCode="AR" term="%22Coney%2C+Leigh+D%2E%22">Coney, Leigh D.</searchLink><br /><searchLink fieldCode="AR" term="%22Maier%2C+Larissa+J%2E%22">Maier, Larissa J.</searchLink><br /><searchLink fieldCode="AR" term="%22Ferris%2C+Jason+A%2E%22">Ferris, Jason A.</searchLink><br /><searchLink fieldCode="AR" term="%22Winstock%2C+Adam+R%2E%22">Winstock, Adam R.</searchLink><br /><searchLink fieldCode="AR" term="%22Barratt%2C+Monica+J%2E%22">Barratt, Monica J.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Human+Psychopharmacology%3A+Clinical+%26+Experimental%22">Human Psychopharmacology: Clinical & Experimental</searchLink>. May2017, Vol. 32 Issue 3, pn/a-N.PAG. 6p.
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  Data: <searchLink fieldCode="DE" term="%22LSD+%28Drug%29%22">LSD (Drug)</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+side+effects%22">Drug side effects</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+abusers%22">Drug abusers</searchLink><br /><searchLink fieldCode="DE" term="%22Pharmaceutical+research%22">Pharmaceutical research</searchLink><br /><searchLink fieldCode="DE" term="%22Hallucinogenic+drugs%22">Hallucinogenic drugs</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective This study aimed to describe self-reported patterns of use and effects of lysergic acid diethylamide (LSD) analogues (AL-LAD, 1P-LSD, and ETH-LAD) and the characteristics of those who use them. Methods An anonymous self-selected online survey of people who use drugs (Global Drug Survey 2016; N = 96,894), which measured perceived drug effects of LSD and its analogues. Results Most LSD analogue users (91%) had also tried LSD. The proportion of U.K. and U.S. respondents reporting LSD analogue use in the last 12 months was higher than for LSD only. LSD analogue users described the effects as psychedelic (93%), over half (55%) obtained it online, and almost all (99%) reported an oral route of administration. The modal duration (8 hr) and time to peak (2 hr) of LSD analogues were not significantly different from LSD. Ratings for pleasurable high, strength of effect, comedown, urge to use more drugs, value for money, and risk of harm following use were significantly lower for LSD analogues compared with LSD. Conclusions LSD analogues were reported as similar in time to peak and duration as LSD but weaker in strength, pleasurable high, and comedown. Future studies should seek to replicate these findings with chemical confirmation and dose measurement. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=123822616
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