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A Short-term Open Trial of Clomipramine in the Treatment of Patients with Panic Attacks.

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Title: A Short-term Open Trial of Clomipramine in the Treatment of Patients with Panic Attacks.
Authors: Judd, F. K., Burrows, G. D., Marriott, P. F., Farrott, P., Blair-West, S., Norman, T. R.
Source: Human Psychopharmacology: Clinical & Experimental. Mar91, Vol. 6 Issue 1, p53-60. 8p.
Subjects: Panic disorders, Health outcome assessment, Anxiety, Phobias, Mental depression, Depressed persons
Abstract: Clomipramine was used to treat 14 patients with panic attacks. Diagnosis was made according Lo DSM-III criteria for agoraphobia with panic attacks or panic disorder uncomplicated. An open evaluation of the drug over an 8-week treatment period was conducted. A total of 10 patients completed the study. Clomipramine was effective in reducing the mean number of panic attacks, the greatest response being observed in the first 2 weeks of treatment. Findings on all outcome measures showed that clomipramine was also effective in alleviating depression secondary to panic attacks, non-specific aspects of anxiety and improving phobic avoidance. There was a suggestion that responders to treatment received tower doses of clomipramine than non-responders. Further studies are required to evaluate this issue and the role of clomipramine in the treatment or panic disorders. [ABSTRACT FROM AUTHOR]
Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: <searchLink fieldCode="JN" term="%22Human+Psychopharmacology%3A+Clinical+%26+Experimental%22">Human Psychopharmacology: Clinical & Experimental</searchLink>. Mar91, Vol. 6 Issue 1, p53-60. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Panic+disorders%22">Panic disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Health+outcome+assessment%22">Health outcome assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety%22">Anxiety</searchLink><br /><searchLink fieldCode="DE" term="%22Phobias%22">Phobias</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Depressed+persons%22">Depressed persons</searchLink>
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  Data: Clomipramine was used to treat 14 patients with panic attacks. Diagnosis was made according Lo DSM-III criteria for agoraphobia with panic attacks or panic disorder uncomplicated. An open evaluation of the drug over an 8-week treatment period was conducted. A total of 10 patients completed the study. Clomipramine was effective in reducing the mean number of panic attacks, the greatest response being observed in the first 2 weeks of treatment. Findings on all outcome measures showed that clomipramine was also effective in alleviating depression secondary to panic attacks, non-specific aspects of anxiety and improving phobic avoidance. There was a suggestion that responders to treatment received tower doses of clomipramine than non-responders. Further studies are required to evaluate this issue and the role of clomipramine in the treatment or panic disorders. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Mar91
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