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Novel treatment strategies in rheumatoid arthritis.

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Title: Novel treatment strategies in rheumatoid arthritis.
Authors: Burmester, Gerd R., Pope, Janet E.
Source: Lancet. 6/10/2017, Vol. 389 Issue 10086, p2338-2348. 11p. 1 Diagram, 1 Graph.
Subjects: Rheumatoid arthritis treatment, Rheumatoid arthritis diagnosis, Drug therapy, Physical therapy, Comorbidity, Methotrexate, Nonsteroidal anti-inflammatory agents, Combination drug therapy, Rheumatoid arthritis
Abstract: New treatment strategies have substantially changed the course of rheumatoid arthritis. Many patients can achieve remission if the disease is recognised early and is treated promptly and continuously; however, some individuals do not respond adequately to treatment. Rapid diagnosis and a treat-to-target approach with tight monitoring and control, can increase the likelihood of remission in patients with rheumatoid arthritis. In this Series paper, we describe new insights into the management of rheumatoid arthritis with targeted therapy approaches using classic and novel medications, and outline the potential effects of precision medicine in this challenging disease. Articles are included that investigate the treat-to-target approach, which includes adding or de-escalating treatment. Rheumatoid arthritis treatment is impeded by delayed diagnosis, problematic access to specialists, and difficulties adhering to treat-to-target principles. Clinical management goals in rheumatoid arthritis include enabling rapid access to optimum diagnosis and care and the well informed use of multiple treatments approved for this disease. [ABSTRACT FROM AUTHOR]
Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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DbLabel: Psychology and Behavioral Sciences Collection
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Novel treatment strategies in rheumatoid arthritis.
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  Data: <searchLink fieldCode="AR" term="%22Burmester%2C+Gerd+R%2E%22">Burmester, Gerd R.</searchLink><br /><searchLink fieldCode="AR" term="%22Pope%2C+Janet+E%2E%22">Pope, Janet E.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 6/10/2017, Vol. 389 Issue 10086, p2338-2348. 11p. 1 Diagram, 1 Graph.
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  Data: <searchLink fieldCode="DE" term="%22Rheumatoid+arthritis+treatment%22">Rheumatoid arthritis treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Rheumatoid+arthritis+diagnosis%22">Rheumatoid arthritis diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+therapy%22">Drug therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Physical+therapy%22">Physical therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink><br /><searchLink fieldCode="DE" term="%22Methotrexate%22">Methotrexate</searchLink><br /><searchLink fieldCode="DE" term="%22Nonsteroidal+anti-inflammatory+agents%22">Nonsteroidal anti-inflammatory agents</searchLink><br /><searchLink fieldCode="DE" term="%22Combination+drug+therapy%22">Combination drug therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Rheumatoid+arthritis%22">Rheumatoid arthritis</searchLink>
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  Data: New treatment strategies have substantially changed the course of rheumatoid arthritis. Many patients can achieve remission if the disease is recognised early and is treated promptly and continuously; however, some individuals do not respond adequately to treatment. Rapid diagnosis and a treat-to-target approach with tight monitoring and control, can increase the likelihood of remission in patients with rheumatoid arthritis. In this Series paper, we describe new insights into the management of rheumatoid arthritis with targeted therapy approaches using classic and novel medications, and outline the potential effects of precision medicine in this challenging disease. Articles are included that investigate the treat-to-target approach, which includes adding or de-escalating treatment. Rheumatoid arthritis treatment is impeded by delayed diagnosis, problematic access to specialists, and difficulties adhering to treat-to-target principles. Clinical management goals in rheumatoid arthritis include enabling rapid access to optimum diagnosis and care and the well informed use of multiple treatments approved for this disease. [ABSTRACT FROM AUTHOR]
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  Group: Ab
  Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=123939094
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/S0140-6736(17)31491-5
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      – Code: eng
        Text: English
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      – SubjectFull: Rheumatoid arthritis treatment
        Type: general
      – SubjectFull: Rheumatoid arthritis diagnosis
        Type: general
      – SubjectFull: Drug therapy
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      – SubjectFull: Physical therapy
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      – SubjectFull: Comorbidity
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      – SubjectFull: Methotrexate
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      – SubjectFull: Nonsteroidal anti-inflammatory agents
        Type: general
      – SubjectFull: Combination drug therapy
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      – SubjectFull: Rheumatoid arthritis
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              Text: 6/10/2017
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              Y: 2017
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