RESISTANCE OF DELAYED-RECTIFIER K+ CURRENT TO CADMIUM IN DROSOPHILA NEURONS.
Saved in:
| Title: | RESISTANCE OF DELAYED-RECTIFIER K+ CURRENT TO CADMIUM IN DROSOPHILA NEURONS. |
|---|---|
| Authors: | Alshuaib, Waleed B., Mathew, Mini V. |
| Source: | International Journal of Neuroscience. 2004, Vol. 114 Issue 4, p481-491. 11p. |
| Subjects: | Cadmium, Neurotoxicology, Potassium, Neurons, Alkali metals, Neurophysiology |
| Abstract: | The delayed-rectifier potassium current (IKDR)is important in repolarizing the membrane potential and determining the level of neuronal excitability. We investigated the effect of cadmium on this potassium current. The whole-cell patch-clamp technique was used to measure IKDR from cultured Drosophila neurons derived from embryonic neuroblasts. The current was measured from neurons before and after the application of 0.1 mM cadmium to the external saline. IKDR was similar in the cadmium-containing saline(383±47 pA) an the control saline (401±60 pA). These results indicate that cadmium neurotoxicity does not specifically affect IKDR in Drosophila neurons. [ABSTRACT FROM AUTHOR] |
| Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 12456253 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: RESISTANCE OF DELAYED-RECTIFIER K<superscript>+</superscript> CURRENT TO CADMIUM IN DROSOPHILA NEURONS. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Alshuaib%2C+Waleed+B%2E%22">Alshuaib, Waleed B.</searchLink><br /><searchLink fieldCode="AR" term="%22Mathew%2C+Mini+V%2E%22">Mathew, Mini V.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Neuroscience%22">International Journal of Neuroscience</searchLink>. 2004, Vol. 114 Issue 4, p481-491. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Cadmium%22">Cadmium</searchLink><br /><searchLink fieldCode="DE" term="%22Neurotoxicology%22">Neurotoxicology</searchLink><br /><searchLink fieldCode="DE" term="%22Potassium%22">Potassium</searchLink><br /><searchLink fieldCode="DE" term="%22Neurons%22">Neurons</searchLink><br /><searchLink fieldCode="DE" term="%22Alkali+metals%22">Alkali metals</searchLink><br /><searchLink fieldCode="DE" term="%22Neurophysiology%22">Neurophysiology</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The delayed-rectifier potassium current (IKDR)is important in repolarizing the membrane potential and determining the level of neuronal excitability. We investigated the effect of cadmium on this potassium current. The whole-cell patch-clamp technique was used to measure IKDR from cultured Drosophila neurons derived from embryonic neuroblasts. The current was measured from neurons before and after the application of 0.1 mM cadmium to the external saline. IKDR was similar in the cadmium-containing saline(383±47 pA) an the control saline (401±60 pA). These results indicate that cadmium neurotoxicity does not specifically affect IKDR in Drosophila neurons. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=12456253 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/00207450490422795 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 481 Subjects: – SubjectFull: Cadmium Type: general – SubjectFull: Neurotoxicology Type: general – SubjectFull: Potassium Type: general – SubjectFull: Neurons Type: general – SubjectFull: Alkali metals Type: general – SubjectFull: Neurophysiology Type: general Titles: – TitleFull: RESISTANCE OF DELAYED-RECTIFIER K+ CURRENT TO CADMIUM IN DROSOPHILA NEURONS. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Alshuaib, Waleed B. – PersonEntity: Name: NameFull: Mathew, Mini V. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2004 Type: published Y: 2004 Identifiers: – Type: issn-print Value: 00207454 Numbering: – Type: volume Value: 114 – Type: issue Value: 4 Titles: – TitleFull: International Journal of Neuroscience Type: main |
| ResultId | 1 |
