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Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru.

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Title: Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru.
Authors: Taype-Rondan, Alvaro, Abbs, Elizabeth, Lazo-Porras, Maria, Checkley, William, Gilman, Robert, Smeeth, Liam, Miranda, J., Bernabe-Ortiz, Antonio, Abbs, Elizabeth Sarah (AUTHOR), Gilman, Robert H (AUTHOR), Miranda, J Jaime (AUTHOR)
Source: Quality of Life Research. Dec2017, Vol. 26 Issue 12, p3439-3447. 9p.
Subjects: Chronic diseases, Quality of life, Urbanization, Health outcome assessment, Mental depression, Chronic bronchitis, Hypertension, Type 2 diabetes, Mental health, Diseases, Longitudinal method, Research funding, Social change, Cross-sectional method
Geographic Terms: Peru
Abstract: Purpose: To evaluate the role of urbanization as an effect modifier for the association between specific chronic conditions and number of conditions with health-related quality of life (QOL).Methods: We analyzed cross-sectional data from the CRONICAS Cohort Study conducted in Lima (highly urbanized), Tumbes (semi-urban), as well as rural and urban sites in Puno. Exposures of interest were chronic bronchitis, depressive mood, hypertension, type 2 diabetes, and a composite variable aggregating the number of chronic conditions (the four exposures plus heart disease and stroke). QOL outcomes were assessed with EuroQol's EQ-5D visual analogue scale (EQ-VAS). We fitted linear regressions with robust variance to evaluate the associations of interest. Study site was assessed as a potential effect modifier using the likelihood-ratio (LR) test.Results: We evaluated data on 2433 subjects: 51.3% were female, mean age was 57.2 years. Study site was found to be an effect modifier only for the association between depressive mood and EQ-VAS score (LR test p < 0.001). Compared to those without depressive mood, participants with depressive mood scored -13.7 points on the EQ-VAS in Lima, -7.9 in urban Puno, -11.0 in semi-urban Tumbes, and -2.7 in rural Puno. Study site was not found to be an effect modifier for the association between the number of chronic conditions and EQ-VAS (LR test p = 0.64).Conclusion: The impact of depressive mood on EQ-VAS was larger in urban than in rural sites, while site was not an effect modifier for the remaining associations. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Quality+of+Life+Research%22&quot;&gt;Quality of Life Research&lt;/searchLink&gt;. Dec2017, Vol. 26 Issue 12, p3439-3447. 9p.
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  Data: &lt;bold&gt;Purpose: &lt;/bold&gt;To evaluate the role of urbanization as an effect modifier for the association between specific chronic conditions and number of conditions with health-related quality of life (QOL).&lt;bold&gt;Methods: &lt;/bold&gt;We analyzed cross-sectional data from the CRONICAS Cohort Study conducted in Lima (highly urbanized), Tumbes (semi-urban), as well as rural and urban sites in Puno. Exposures of interest were chronic bronchitis, depressive mood, hypertension, type 2 diabetes, and a composite variable aggregating the number of chronic conditions (the four exposures plus heart disease and stroke). QOL outcomes were assessed with EuroQol&#39;s EQ-5D visual analogue scale (EQ-VAS). We fitted linear regressions with robust variance to evaluate the associations of interest. Study site was assessed as a potential effect modifier using the likelihood-ratio (LR) test.&lt;bold&gt;Results: &lt;/bold&gt;We evaluated data on 2433 subjects: 51.3% were female, mean age was 57.2&#160;years. Study site was found to be an effect modifier only for the association between depressive mood and EQ-VAS score (LR test p&#160;&lt;&#160;0.001). Compared to those without depressive mood, participants with depressive mood scored -13.7 points on the EQ-VAS in Lima, -7.9 in urban Puno, -11.0 in semi-urban Tumbes, and -2.7 in rural Puno. Study site was not found to be an effect modifier for the association between the number of chronic conditions and EQ-VAS (LR test p&#160;=&#160;0.64).&lt;bold&gt;Conclusion: &lt;/bold&gt;The impact of depressive mood on EQ-VAS was larger in urban than in rural sites, while site was not an effect modifier for the remaining associations. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=126170749
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        Value: 10.1007/s11136-017-1649-7
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