View in EDS

Lineage divergence of activity-driven transcription and evolution of cognitive ability.

Saved in:
Bibliographic Details
Title: Lineage divergence of activity-driven transcription and evolution of cognitive ability.
Authors: Hardingham, Giles E., Pruunsild, Priit, Greenberg, Michael E., Bading, Hilmar
Source: Nature Reviews Neuroscience. Jan2018, Vol. 19 Issue 1, p9-15. 7p. 2 Diagrams, 1 Chart.
Subjects: RNA physiology, Animals, Cell differentiation, Cognition, Genes, Immunity, Mice, Neural transmission, Research funding
Abstract: Excitation-transcription coupling shapes network formation during brain development and controls neuronal survival, synaptic function and cognitive skills in the adult. New studies have uncovered differences in the transcriptional responses to synaptic activity between humans and mice. These differences are caused both by the emergence of lineage-specific activity-regulated genes and by the acquisition of signal-responsive DNA elements in gene regulatory regions that determine whether a gene can be transcriptionally induced by synaptic activity or alter the extent of its inducibility. Such evolutionary divergence may have contributed to lineage-related advancements in cognitive abilities. [ABSTRACT FROM AUTHOR]
Copyright of Nature Reviews Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 126776678
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Lineage divergence of activity-driven transcription and evolution of cognitive ability.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Hardingham%2C+Giles+E%2E%22">Hardingham, Giles E.</searchLink><br /><searchLink fieldCode="AR" term="%22Pruunsild%2C+Priit%22">Pruunsild, Priit</searchLink><br /><searchLink fieldCode="AR" term="%22Greenberg%2C+Michael+E%2E%22">Greenberg, Michael E.</searchLink><br /><searchLink fieldCode="AR" term="%22Bading%2C+Hilmar%22">Bading, Hilmar</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Nature+Reviews+Neuroscience%22">Nature Reviews Neuroscience</searchLink>. Jan2018, Vol. 19 Issue 1, p9-15. 7p. 2 Diagrams, 1 Chart.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22RNA+physiology%22">RNA physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Animals%22">Animals</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+differentiation%22">Cell differentiation</searchLink><br /><searchLink fieldCode="DE" term="%22Cognition%22">Cognition</searchLink><br /><searchLink fieldCode="DE" term="%22Genes%22">Genes</searchLink><br /><searchLink fieldCode="DE" term="%22Immunity%22">Immunity</searchLink><br /><searchLink fieldCode="DE" term="%22Mice%22">Mice</searchLink><br /><searchLink fieldCode="DE" term="%22Neural+transmission%22">Neural transmission</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Excitation-transcription coupling shapes network formation during brain development and controls neuronal survival, synaptic function and cognitive skills in the adult. New studies have uncovered differences in the transcriptional responses to synaptic activity between humans and mice. These differences are caused both by the emergence of lineage-specific activity-regulated genes and by the acquisition of signal-responsive DNA elements in gene regulatory regions that determine whether a gene can be transcriptionally induced by synaptic activity or alter the extent of its inducibility. Such evolutionary divergence may have contributed to lineage-related advancements in cognitive abilities. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Nature Reviews Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=126776678
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/nrn.2017.138
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 9
    Subjects:
      – SubjectFull: RNA physiology
        Type: general
      – SubjectFull: Animals
        Type: general
      – SubjectFull: Cell differentiation
        Type: general
      – SubjectFull: Cognition
        Type: general
      – SubjectFull: Genes
        Type: general
      – SubjectFull: Immunity
        Type: general
      – SubjectFull: Mice
        Type: general
      – SubjectFull: Neural transmission
        Type: general
      – SubjectFull: Research funding
        Type: general
    Titles:
      – TitleFull: Lineage divergence of activity-driven transcription and evolution of cognitive ability.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hardingham, Giles E.
      – PersonEntity:
          Name:
            NameFull: Pruunsild, Priit
      – PersonEntity:
          Name:
            NameFull: Greenberg, Michael E.
      – PersonEntity:
          Name:
            NameFull: Bading, Hilmar
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: Jan2018
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-print
              Value: 1471003X
          Numbering:
            – Type: volume
              Value: 19
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature Reviews Neuroscience
              Type: main
ResultId 1