Malaria.
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| Title: | Malaria. |
|---|---|
| Authors: | Ashley, Elizabeth A., Aung Pyae Phyo, Woodrow, Charles J., Pyae Phyo, Aung |
| Source: | Lancet. 4/21/2018, Vol. 391 Issue 10130, p1608-1621. 14p. |
| Subjects: | Malaria prevention, Insecticide-treated mosquito nets, Resuscitation, Drug resistance, Malaria treatment |
| Abstract: | Following unsuccessful eradication attempts there was a resurgence of malaria towards the end of the 20th century. Renewed control efforts using a range of improved tools, such as long-lasting insecticide-treated bednets and artemisinin-based combination therapies, have more than halved the global burden of disease, but it remains high with 445 000 deaths and more than 200 million cases in 2016. Pitfalls in individual patient management are delayed diagnosis and overzealous fluid resuscitation in severe malaria. Even in the absence of drug resistance, parasite recurrence can occur, owing to high parasite densities, low host immunity, or suboptimal drug concentrations. Malaria elimination is firmly back as a mainstream policy but resistance to the artemisinin derivatives, their partner drugs, and insecticides present major challenges. Vaccine development continues on several fronts but none of the candidates developed to date have been shown to provide long-lasting benefits at a population level. Increased resources and unprecedented levels of regional cooperation and societal commitment will be needed if further substantial inroads into the malaria burden are to be made. [ABSTRACT FROM AUTHOR] |
| Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 129419648 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Malaria. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ashley%2C+Elizabeth+A%2E%22">Ashley, Elizabeth A.</searchLink><br /><searchLink fieldCode="AR" term="%22Aung+Pyae+Phyo%22">Aung Pyae Phyo</searchLink><br /><searchLink fieldCode="AR" term="%22Woodrow%2C+Charles+J%2E%22">Woodrow, Charles J.</searchLink><br /><searchLink fieldCode="AR" term="%22Pyae+Phyo%2C+Aung%22">Pyae Phyo, Aung</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 4/21/2018, Vol. 391 Issue 10130, p1608-1621. 14p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Malaria+prevention%22">Malaria prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Insecticide-treated+mosquito+nets%22">Insecticide-treated mosquito nets</searchLink><br /><searchLink fieldCode="DE" term="%22Resuscitation%22">Resuscitation</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+resistance%22">Drug resistance</searchLink><br /><searchLink fieldCode="DE" term="%22Malaria+treatment%22">Malaria treatment</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Following unsuccessful eradication attempts there was a resurgence of malaria towards the end of the 20th century. Renewed control efforts using a range of improved tools, such as long-lasting insecticide-treated bednets and artemisinin-based combination therapies, have more than halved the global burden of disease, but it remains high with 445 000 deaths and more than 200 million cases in 2016. Pitfalls in individual patient management are delayed diagnosis and overzealous fluid resuscitation in severe malaria. Even in the absence of drug resistance, parasite recurrence can occur, owing to high parasite densities, low host immunity, or suboptimal drug concentrations. Malaria elimination is firmly back as a mainstream policy but resistance to the artemisinin derivatives, their partner drugs, and insecticides present major challenges. Vaccine development continues on several fronts but none of the candidates developed to date have been shown to provide long-lasting benefits at a population level. Increased resources and unprecedented levels of regional cooperation and societal commitment will be needed if further substantial inroads into the malaria burden are to be made. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=129419648 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/S0140-6736(18)30324-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 14 StartPage: 1608 Subjects: – SubjectFull: Malaria prevention Type: general – SubjectFull: Insecticide-treated mosquito nets Type: general – SubjectFull: Resuscitation Type: general – SubjectFull: Drug resistance Type: general – SubjectFull: Malaria treatment Type: general Titles: – TitleFull: Malaria. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ashley, Elizabeth A. – PersonEntity: Name: NameFull: Aung Pyae Phyo – PersonEntity: Name: NameFull: Woodrow, Charles J. – PersonEntity: Name: NameFull: Pyae Phyo, Aung IsPartOfRelationships: – BibEntity: Dates: – D: 21 M: 04 Text: 4/21/2018 Type: published Y: 2018 Identifiers: – Type: issn-print Value: 01406736 Numbering: – Type: volume Value: 391 – Type: issue Value: 10130 Titles: – TitleFull: Lancet Type: main |
| ResultId | 1 |
