Increased non‐fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs.
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| Title: | Increased non‐fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs. |
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| Authors: | Rafful, Claudia, Orozco, Ricardo, Rangel, Gudelia, Davidson, Peter, Werb, Dan, Beletsky, Leo, Strathdee, Steffanie A. |
| Source: | Addiction. Jun2018, Vol. 113 Issue 6, p1056-1063. 8p. 3 Charts. |
| Subjects: | Drug overdose risk factors, Involuntary treatment, Intravenous drug abusers, Drug abuse treatment, Women & drugs, Heroin abuse, Substance use of men, Methamphetamine abuse, Longitudinal method, Confidence intervals, Descriptive statistics, Odds ratio |
| Geographic Terms: | Mexico |
| Abstract: | Abstract: Aim: To assess the effect of involuntary drug treatment (IDT) on non‐fatal overdose among people who inject drugs (PWID). Design: Longitudinal study. Setting: Tijuana, Mexico. Participants: Baseline sample of 671 PWID included 258 (38.4%) women and 413 (61.6%) men. Measurements: Primary independent variables were reported recent (i.e. past 6 months) non‐fatal overdose event (dependent variable) and IDT. Substance use the day of the non‐fatal overdose was also examined. Findings: From 2011 to 2017, 213 participants (31.7%) reported a recent non‐fatal overdose and 103 (15.4%) reported recent IDT. Heroin, in combination with methamphetamine and tranquilizers, were the drugs most reported at the day of the event. IDT significantly increased the odds of reporting a non‐fatal overdose event [adjusted odds ratio (aOR) = 1.76; 95% confidence interval (CI) = 1.04–2.96]. Odds of non‐fatal overdose also increased independently for each additional injection per day (aOR = 1.05; 95% CI = 1.02–1.08), recent tranquilizer use (aOR = 1.92; 95% CI = 1.41–2.61) and using hit doctors (aOR = 1.68; 95% CI = 1.29–2.18) and decreased with age (aOR = 0.97 per year, 95% CI = 0.95–0.99). Conclusions: Recent involuntary drug treatment in Mexico is a risk factor for non‐fatal drug overdose. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Abstract: Aim: To assess the effect of involuntary drug treatment (IDT) on non‐fatal overdose among people who inject drugs (PWID). Design: Longitudinal study. Setting: Tijuana, Mexico. Participants: Baseline sample of 671 PWID included 258 (38.4%) women and 413 (61.6%) men. Measurements: Primary independent variables were reported recent (i.e. past 6 months) non‐fatal overdose event (dependent variable) and IDT. Substance use the day of the non‐fatal overdose was also examined. Findings: From 2011 to 2017, 213 participants (31.7%) reported a recent non‐fatal overdose and 103 (15.4%) reported recent IDT. Heroin, in combination with methamphetamine and tranquilizers, were the drugs most reported at the day of the event. IDT significantly increased the odds of reporting a non‐fatal overdose event [adjusted odds ratio (aOR) = 1.76; 95% confidence interval (CI) = 1.04–2.96]. Odds of non‐fatal overdose also increased independently for each additional injection per day (aOR = 1.05; 95% CI = 1.02–1.08), recent tranquilizer use (aOR = 1.92; 95% CI = 1.41–2.61) and using hit doctors (aOR = 1.68; 95% CI = 1.29–2.18) and decreased with age (aOR = 0.97 per year, 95% CI = 0.95–0.99). Conclusions: Recent involuntary drug treatment in Mexico is a risk factor for non‐fatal drug overdose. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 09652140 |
| DOI: | 10.1111/add.14159 |
