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Increased non‐fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs.

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Title: Increased non‐fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs.
Authors: Rafful, Claudia, Orozco, Ricardo, Rangel, Gudelia, Davidson, Peter, Werb, Dan, Beletsky, Leo, Strathdee, Steffanie A.
Source: Addiction. Jun2018, Vol. 113 Issue 6, p1056-1063. 8p. 3 Charts.
Subjects: Drug overdose risk factors, Involuntary treatment, Intravenous drug abusers, Drug abuse treatment, Women & drugs, Heroin abuse, Substance use of men, Methamphetamine abuse, Longitudinal method, Confidence intervals, Descriptive statistics, Odds ratio
Geographic Terms: Mexico
Abstract: Abstract: Aim: To assess the effect of involuntary drug treatment (IDT) on non‐fatal overdose among people who inject drugs (PWID). Design: Longitudinal study. Setting: Tijuana, Mexico. Participants: Baseline sample of 671 PWID included 258 (38.4%) women and 413 (61.6%) men. Measurements: Primary independent variables were reported recent (i.e. past 6 months) non‐fatal overdose event (dependent variable) and IDT. Substance use the day of the non‐fatal overdose was also examined. Findings: From 2011 to 2017, 213 participants (31.7%) reported a recent non‐fatal overdose and 103 (15.4%) reported recent IDT. Heroin, in combination with methamphetamine and tranquilizers, were the drugs most reported at the day of the event. IDT significantly increased the odds of reporting a non‐fatal overdose event [adjusted odds ratio (aOR) = 1.76; 95% confidence interval (CI) = 1.04–2.96]. Odds of non‐fatal overdose also increased independently for each additional injection per day (aOR = 1.05; 95% CI = 1.02–1.08), recent tranquilizer use (aOR = 1.92; 95% CI = 1.41–2.61) and using hit doctors (aOR = 1.68; 95% CI = 1.29–2.18) and decreased with age (aOR = 0.97 per year, 95% CI = 0.95–0.99). Conclusions: Recent involuntary drug treatment in Mexico is a risk factor for non‐fatal drug overdose. [ABSTRACT FROM AUTHOR]
Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Increased non‐fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs.
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  Data: <searchLink fieldCode="AR" term="%22Rafful%2C+Claudia%22">Rafful, Claudia</searchLink><br /><searchLink fieldCode="AR" term="%22Orozco%2C+Ricardo%22">Orozco, Ricardo</searchLink><br /><searchLink fieldCode="AR" term="%22Rangel%2C+Gudelia%22">Rangel, Gudelia</searchLink><br /><searchLink fieldCode="AR" term="%22Davidson%2C+Peter%22">Davidson, Peter</searchLink><br /><searchLink fieldCode="AR" term="%22Werb%2C+Dan%22">Werb, Dan</searchLink><br /><searchLink fieldCode="AR" term="%22Beletsky%2C+Leo%22">Beletsky, Leo</searchLink><br /><searchLink fieldCode="AR" term="%22Strathdee%2C+Steffanie+A%2E%22">Strathdee, Steffanie A.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Addiction%22">Addiction</searchLink>. Jun2018, Vol. 113 Issue 6, p1056-1063. 8p. 3 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Drug+overdose+risk+factors%22">Drug overdose risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Involuntary+treatment%22">Involuntary treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Intravenous+drug+abusers%22">Intravenous drug abusers</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+abuse+treatment%22">Drug abuse treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Women+%26+drugs%22">Women & drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Heroin+abuse%22">Heroin abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Substance+use+of+men%22">Substance use of men</searchLink><br /><searchLink fieldCode="DE" term="%22Methamphetamine+abuse%22">Methamphetamine abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Odds+ratio%22">Odds ratio</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Mexico%22">Mexico</searchLink>
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  Data: Abstract: Aim: To assess the effect of involuntary drug treatment (IDT) on non‐fatal overdose among people who inject drugs (PWID). Design: Longitudinal study. Setting: Tijuana, Mexico. Participants: Baseline sample of 671 PWID included 258 (38.4%) women and 413 (61.6%) men. Measurements: Primary independent variables were reported recent (i.e. past 6 months) non‐fatal overdose event (dependent variable) and IDT. Substance use the day of the non‐fatal overdose was also examined. Findings: From 2011 to 2017, 213 participants (31.7%) reported a recent non‐fatal overdose and 103 (15.4%) reported recent IDT. Heroin, in combination with methamphetamine and tranquilizers, were the drugs most reported at the day of the event. IDT significantly increased the odds of reporting a non‐fatal overdose event [adjusted odds ratio (aOR) = 1.76; 95% confidence interval (CI) = 1.04–2.96]. Odds of non‐fatal overdose also increased independently for each additional injection per day (aOR = 1.05; 95% CI = 1.02–1.08), recent tranquilizer use (aOR = 1.92; 95% CI = 1.41–2.61) and using hit doctors (aOR = 1.68; 95% CI = 1.29–2.18) and decreased with age (aOR = 0.97 per year, 95% CI = 0.95–0.99). Conclusions: Recent involuntary drug treatment in Mexico is a risk factor for non‐fatal drug overdose. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1111/add.14159
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 8
        StartPage: 1056
    Subjects:
      – SubjectFull: Drug overdose risk factors
        Type: general
      – SubjectFull: Involuntary treatment
        Type: general
      – SubjectFull: Intravenous drug abusers
        Type: general
      – SubjectFull: Drug abuse treatment
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      – SubjectFull: Women & drugs
        Type: general
      – SubjectFull: Heroin abuse
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      – SubjectFull: Substance use of men
        Type: general
      – SubjectFull: Methamphetamine abuse
        Type: general
      – SubjectFull: Longitudinal method
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Odds ratio
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      – SubjectFull: Mexico
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      – TitleFull: Increased non‐fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs.
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              Text: Jun2018
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              Y: 2018
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