View in EDS HTML Full Text PDF Full Text

Resting Heart Rate Variability (HRV) in Adolescents and Young Adults from a Genetically-Informed Perspective.

Saved in:
Bibliographic Details
Title: Resting Heart Rate Variability (HRV) in Adolescents and Young Adults from a Genetically-Informed Perspective.
Authors: Bourdon, Jessica L., Moore, Ashlee A., Eastman, Meridith, Savage, Jeanne E., Hazlett, Laura, Vrana, Scott R., Hettema, John M., Roberson-Nay, Roxann
Source: Behavior Genetics. Sep2018, Vol. 48 Issue 5, p386-396. 11p.
Subjects: Heritability, Psychophysiology, Heart beat, Health of young adults, Adolescent physiology
Abstract: Reduced heart rate variability (HRV) is associated with cardiac morbidity, mortality, and negative psychopathology. Most research concerning genetic influences on HRV has focused on adult populations, with fewer studies investigating the developmental period of adolescence and emerging adulthood. The current study estimated the genetic and environmental contributions to resting HRV in a sample of twins using various HRV time domain metrics to assess autonomic function across two different time measurement intervals (2.5- and 10-min). Five metrics of resting HRV [mean interbeat interval (IBI), the standard deviation of normal IBIs (SDNN), root square mean of successive differences between IBIs (RMSSD), cardiac vagal index (CVI), and cardiac sympathetic index (CSI)] were assessed in 421 twin pairs aged 14-20 during a baseline electrocardiogram. This was done for four successive 2.5-min intervals as well as the overall 10-min interval. Heritability (h2) appeared consistent across intervals within each metric with the following estimates (collapsed across time intervals): mean IBI (h2 = 0.36-0.46), SDNN (h2 = 0.23-0.30), RMSSD (h2 = 0.36-0.39), CVI (h2 = 0.37-0.42), CSI (h2 = 0.33-0.46). Beyond additive genetic contributions, unique environment also was an important influence on HRV. Within each metric, a multivariate Cholesky decomposition further revealed evidence of genetic stability across the four successive 2.5-min intervals. The same models showed evidence for both genetic and environmental stability with some environmental attenuation and innovation. All measures of HRV were moderately heritable across time, with further analyses revealing consistent patterns of genetic and environmental influences over time. This study confirms that in an adolescent sample, the time interval used (2.5- vs. 10-min) to measure HRV time domain metrics does not affect the relative proportions of genetic and environmental influences. [ABSTRACT FROM AUTHOR]
Copyright of Behavior Genetics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 130970587
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Resting Heart Rate Variability (HRV) in Adolescents and Young Adults from a Genetically-Informed Perspective.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Bourdon%2C+Jessica+L%2E%22">Bourdon, Jessica L.</searchLink><br /><searchLink fieldCode="AR" term="%22Moore%2C+Ashlee+A%2E%22">Moore, Ashlee A.</searchLink><br /><searchLink fieldCode="AR" term="%22Eastman%2C+Meridith%22">Eastman, Meridith</searchLink><br /><searchLink fieldCode="AR" term="%22Savage%2C+Jeanne+E%2E%22">Savage, Jeanne E.</searchLink><br /><searchLink fieldCode="AR" term="%22Hazlett%2C+Laura%22">Hazlett, Laura</searchLink><br /><searchLink fieldCode="AR" term="%22Vrana%2C+Scott+R%2E%22">Vrana, Scott R.</searchLink><br /><searchLink fieldCode="AR" term="%22Hettema%2C+John+M%2E%22">Hettema, John M.</searchLink><br /><searchLink fieldCode="AR" term="%22Roberson-Nay%2C+Roxann%22">Roberson-Nay, Roxann</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Behavior+Genetics%22">Behavior Genetics</searchLink>. Sep2018, Vol. 48 Issue 5, p386-396. 11p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Heritability%22">Heritability</searchLink><br /><searchLink fieldCode="DE" term="%22Psychophysiology%22">Psychophysiology</searchLink><br /><searchLink fieldCode="DE" term="%22Heart+beat%22">Heart beat</searchLink><br /><searchLink fieldCode="DE" term="%22Health+of+young+adults%22">Health of young adults</searchLink><br /><searchLink fieldCode="DE" term="%22Adolescent+physiology%22">Adolescent physiology</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Reduced heart rate variability (HRV) is associated with cardiac morbidity, mortality, and negative psychopathology. Most research concerning genetic influences on HRV has focused on adult populations, with fewer studies investigating the developmental period of adolescence and emerging adulthood. The current study estimated the genetic and environmental contributions to resting HRV in a sample of twins using various HRV time domain metrics to assess autonomic function across two different time measurement intervals (2.5- and 10-min). Five metrics of resting HRV [mean interbeat interval (IBI), the standard deviation of normal IBIs (SDNN), root square mean of successive differences between IBIs (RMSSD), cardiac vagal index (CVI), and cardiac sympathetic index (CSI)] were assessed in 421 twin pairs aged 14-20 during a baseline electrocardiogram. This was done for four successive 2.5-min intervals as well as the overall 10-min interval. Heritability (h2) appeared consistent across intervals within each metric with the following estimates (collapsed across time intervals): mean IBI (h2 = 0.36-0.46), SDNN (h2 = 0.23-0.30), RMSSD (h2 = 0.36-0.39), CVI (h2 = 0.37-0.42), CSI (h2 = 0.33-0.46). Beyond additive genetic contributions, unique environment also was an important influence on HRV. Within each metric, a multivariate Cholesky decomposition further revealed evidence of genetic stability across the four successive 2.5-min intervals. The same models showed evidence for both genetic and environmental stability with some environmental attenuation and innovation. All measures of HRV were moderately heritable across time, with further analyses revealing consistent patterns of genetic and environmental influences over time. This study confirms that in an adolescent sample, the time interval used (2.5- vs. 10-min) to measure HRV time domain metrics does not affect the relative proportions of genetic and environmental influences. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Behavior Genetics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=130970587
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10519-018-9915-1
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 386
    Subjects:
      – SubjectFull: Heritability
        Type: general
      – SubjectFull: Psychophysiology
        Type: general
      – SubjectFull: Heart beat
        Type: general
      – SubjectFull: Health of young adults
        Type: general
      – SubjectFull: Adolescent physiology
        Type: general
    Titles:
      – TitleFull: Resting Heart Rate Variability (HRV) in Adolescents and Young Adults from a Genetically-Informed Perspective.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Bourdon, Jessica L.
      – PersonEntity:
          Name:
            NameFull: Moore, Ashlee A.
      – PersonEntity:
          Name:
            NameFull: Eastman, Meridith
      – PersonEntity:
          Name:
            NameFull: Savage, Jeanne E.
      – PersonEntity:
          Name:
            NameFull: Hazlett, Laura
      – PersonEntity:
          Name:
            NameFull: Vrana, Scott R.
      – PersonEntity:
          Name:
            NameFull: Hettema, John M.
      – PersonEntity:
          Name:
            NameFull: Roberson-Nay, Roxann
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: Sep2018
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-print
              Value: 00018244
          Numbering:
            – Type: volume
              Value: 48
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Behavior Genetics
              Type: main
ResultId 1