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Effects of Upper Airway Surgery on Daytime Sleepiness in Nonobese Patients with Obstructive Sleep Apnea/Hypopnea Syndrome.

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Title: Effects of Upper Airway Surgery on Daytime Sleepiness in Nonobese Patients with Obstructive Sleep Apnea/Hypopnea Syndrome.
Authors: Lai, Chi-Chih, Lin, Pei-Wen, Lin, Hsin-Ching, Friedman, Michael, Chang, Hsueh-Wen, Salapatas, Anna M., Lin, Meng-Chih, Huang, Kuo-Tung
Source: Annals of Otology, Rhinology & Laryngology. Dec2018, Vol. 127 Issue 12, p912-918. 7p.
Subjects: Academic medical centers, Hypersomnia, Operative otolaryngology, Postoperative period, Sleep apnea syndromes, Snoring, Statistics, Polysomnography, Data analysis, Retrospective studies, Continuous positive airway pressure, Preoperative period, Tertiary care, Mann Whitney U Test, Diagnosis
Abstract: Introduction: The aim of this study was to evaluate the effects of upper airway surgery on daytime sleepiness in nonobese patients with obstructive sleep apnea/hypopnea syndrome (OSA). Methods: This retrospective study included 121 consecutive adult nonobese patients with OSA from a tertiary academic medical center. Patients with OSA who refused continuous positive airway pressure therapy, or in whom it was unsuccessful, and then underwent OSA surgery were enrolled. Evaluations of excessive daytime sleepiness using the Epworth Sleepiness Scale (ESS) and major parameters of objective full-night polysomnography were collected preoperatively and at least 3 months postoperatively. Statistical analysis was performed using the Wilcoxon signed rank test and Wilcoxon rank sum test. Results: When pre- and postoperative ESS and polysomnographic parameters were compared in all patients, ESS scores, apnea/hypopnea index, and snoring index showed statistically significant improvements (P = .007, P < .001, and P < .001, respectively). When patients were classified into mild, moderate, and severe OSA groups, snoring index had statistically significant improvements in all 3 groups, and apnea/hypopnea index had statistically significant decreases in the moderate and severe OSA groups. Although reductions in ESS scores were found in all 3 groups, the most statistically significant improvement was noted only in the severe OSA group. Conclusions: OSA surgery can improve daytime sleepiness in nonobese patients with OSA, especially for patients with severe OSA. This study elucidates the effects of OSA surgery on daytime sleepiness by excluding the major confounding factor of obesity. This study adds to the literature on the effects of upper airway surgery for nonobese patients with OSA on daytime quality of life. [ABSTRACT FROM AUTHOR]
Copyright of Annals of Otology, Rhinology & Laryngology is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Effects of Upper Airway Surgery on Daytime Sleepiness in Nonobese Patients with Obstructive Sleep Apnea/Hypopnea Syndrome.
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  Data: Introduction: The aim of this study was to evaluate the effects of upper airway surgery on daytime sleepiness in nonobese patients with obstructive sleep apnea/hypopnea syndrome (OSA). Methods: This retrospective study included 121 consecutive adult nonobese patients with OSA from a tertiary academic medical center. Patients with OSA who refused continuous positive airway pressure therapy, or in whom it was unsuccessful, and then underwent OSA surgery were enrolled. Evaluations of excessive daytime sleepiness using the Epworth Sleepiness Scale (ESS) and major parameters of objective full-night polysomnography were collected preoperatively and at least 3 months postoperatively. Statistical analysis was performed using the Wilcoxon signed rank test and Wilcoxon rank sum test. Results: When pre- and postoperative ESS and polysomnographic parameters were compared in all patients, ESS scores, apnea/hypopnea index, and snoring index showed statistically significant improvements (P = .007, P &lt; .001, and P &lt; .001, respectively). When patients were classified into mild, moderate, and severe OSA groups, snoring index had statistically significant improvements in all 3 groups, and apnea/hypopnea index had statistically significant decreases in the moderate and severe OSA groups. Although reductions in ESS scores were found in all 3 groups, the most statistically significant improvement was noted only in the severe OSA group. Conclusions: OSA surgery can improve daytime sleepiness in nonobese patients with OSA, especially for patients with severe OSA. This study elucidates the effects of OSA surgery on daytime sleepiness by excluding the major confounding factor of obesity. This study adds to the literature on the effects of upper airway surgery for nonobese patients with OSA on daytime quality of life. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Annals of Otology, Rhinology &amp; Laryngology is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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    Identifiers:
      – Type: doi
        Value: 10.1177/0003489418800089
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 912
    Subjects:
      – SubjectFull: Academic medical centers
        Type: general
      – SubjectFull: Hypersomnia
        Type: general
      – SubjectFull: Operative otolaryngology
        Type: general
      – SubjectFull: Postoperative period
        Type: general
      – SubjectFull: Sleep apnea syndromes
        Type: general
      – SubjectFull: Snoring
        Type: general
      – SubjectFull: Statistics
        Type: general
      – SubjectFull: Polysomnography
        Type: general
      – SubjectFull: Data analysis
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Continuous positive airway pressure
        Type: general
      – SubjectFull: Preoperative period
        Type: general
      – SubjectFull: Tertiary care
        Type: general
      – SubjectFull: Mann Whitney U Test
        Type: general
      – SubjectFull: Diagnosis
        Type: general
    Titles:
      – TitleFull: Effects of Upper Airway Surgery on Daytime Sleepiness in Nonobese Patients with Obstructive Sleep Apnea/Hypopnea Syndrome.
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            NameFull: Lai, Chi-Chih
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            NameFull: Friedman, Michael
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            NameFull: Chang, Hsueh-Wen
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            – D: 01
              M: 12
              Text: Dec2018
              Type: published
              Y: 2018
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            – TitleFull: Annals of Otology, Rhinology & Laryngology
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