Bibliographic Details
| Title: |
Different cutoffs of the reflux finding score for diagnosing laryngopharyngeal reflux disease should be used for different genders. |
| Authors: |
Cheng-Kai Gao, Yan-Fei Li, Lu Wang, Xiao-Yan Han, Ting Wu, Fang-Fang Zeng, Xiang-Ping Li |
| Source: |
Acta Oto-Laryngologica (Supplement). Sep2018, Vol. 138 Issue 9, p848-854. 7p. 5 Charts, 2 Graphs. |
| Subjects: |
Gastroesophageal reflux diagnosis, Fiber optics, Laryngoscopy, Reliability (Personality trait), Sex distribution, Symptoms, Receiver operating characteristic curves, Intraclass correlation |
| Abstract: |
Objectives: To assess the differences in Reflux Finding Score (RFS) between the genders and determine the suitable RFS threshold for diagnosing laryngopharyngeal reflux disease (LPRD) in each gender. Methods: Asymptomatic volunteers and patients with LPRD, confirmed with an oropharyngeal Dx-pH monitoring system, were included. All study subjects underwent transnasal flexible fiber-optic video laryngoscopy. Reliability was assessed with intra-class correlation coefficients (ICCs) and Bland-Altman plots. The RFS cutoffs for determining the presence and absence of LPRD between the two genders were examined by receiver operating characteristic (ROC) analysis. Results: One hundred seven asymptomatic volunteers and fifty-five LPRD patients were recruited. The mean RFS for LPRD subjects (9.4±3.2) was significantly higher than that for control subjects (7.1 ±2.6; p<0.001). The mean RFS for asymptomatic females (6.1 ±2.7) was significantly lower than that for males (7.7 ±2.5; p < 0.001). The mean RFS for female subjects with LPRD (7.8 ±2.6) was lower than that for males (11.0±2.8; p<0.001). According to ROC analysis, the best cutoffs were 9.0 for males and 6.0 for females. Conclusions: There was a significant difference in the RFS cutoff between the genders. For male subjects, we recommend a cutoff of 9.0 for diagnosing LPRD, and for female subjects, we recommend a cutoff of 6.0. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
