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Current perspectives on psychedelic therapy: use of serotonergic hallucinogens in clinical interventions.

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Title: Current perspectives on psychedelic therapy: use of serotonergic hallucinogens in clinical interventions.
Authors: Garcia-Romeu, Albert, Richards, William A.
Source: International Review of Psychiatry. Aug2018, Vol. 30 Issue 4, p291-316. 26p.
Subjects: Serotonin agonists, Mental illness drug therapy, Hallucinogenic drugs, Mathematical models, Medical practice, Psychoanalytic interpretation, Psychology, Serotonin antagonists, Treatment effectiveness, Therapeutics
Abstract: Humans have used serotonergic hallucinogens (i.e. psychedelics) for spiritual, ceremonial, and recreational purposes for thousands of years, but their administration as part of a structured therapeutic intervention is still a relatively novel practice within Western medical and psychological frameworks. In the mid-20th century, considerable advances were made in developing therapeutic approaches integrating administration of low (psycholytic) and high (psychedelic) doses of serotonergic hallucinogens for treatment of a variety of conditions, often incorporating psychoanalytic concepts prevalent at that time. This work contributed seminal insights regarding how these substances may be employed with efficacy and safety in targeted therapeutic interventions, including the importance of optimizing set (frame of mind) and setting (therapeutic environment). More recently, clinical and pharmacological research has revisited the effects and therapeutic potential of psychedelics utilizing a variety of approaches. The current article provides an overview of past and present models of psychedelic therapy, and discusses important considerations for future interventions incorporating the use of psychedelics in research and clinical practice. [ABSTRACT FROM AUTHOR]
Copyright of International Review of Psychiatry is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Current perspectives on psychedelic therapy: use of serotonergic hallucinogens in clinical interventions.
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  Data: <searchLink fieldCode="AR" term="%22Garcia-Romeu%2C+Albert%22">Garcia-Romeu, Albert</searchLink><br /><searchLink fieldCode="AR" term="%22Richards%2C+William+A%2E%22">Richards, William A.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22International+Review+of+Psychiatry%22">International Review of Psychiatry</searchLink>. Aug2018, Vol. 30 Issue 4, p291-316. 26p.
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  Data: <searchLink fieldCode="DE" term="%22Serotonin+agonists%22">Serotonin agonists</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+illness+drug+therapy%22">Mental illness drug therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Hallucinogenic+drugs%22">Hallucinogenic drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Mathematical+models%22">Mathematical models</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+practice%22">Medical practice</searchLink><br /><searchLink fieldCode="DE" term="%22Psychoanalytic+interpretation%22">Psychoanalytic interpretation</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology%22">Psychology</searchLink><br /><searchLink fieldCode="DE" term="%22Serotonin+antagonists%22">Serotonin antagonists</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Humans have used serotonergic hallucinogens (i.e. psychedelics) for spiritual, ceremonial, and recreational purposes for thousands of years, but their administration as part of a structured therapeutic intervention is still a relatively novel practice within Western medical and psychological frameworks. In the mid-20th century, considerable advances were made in developing therapeutic approaches integrating administration of low (psycholytic) and high (psychedelic) doses of serotonergic hallucinogens for treatment of a variety of conditions, often incorporating psychoanalytic concepts prevalent at that time. This work contributed seminal insights regarding how these substances may be employed with efficacy and safety in targeted therapeutic interventions, including the importance of optimizing set (frame of mind) and setting (therapeutic environment). More recently, clinical and pharmacological research has revisited the effects and therapeutic potential of psychedelics utilizing a variety of approaches. The current article provides an overview of past and present models of psychedelic therapy, and discusses important considerations for future interventions incorporating the use of psychedelics in research and clinical practice. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of International Review of Psychiatry is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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        Value: 10.1080/09540261.2018.1486289
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      – Code: eng
        Text: English
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      – SubjectFull: Mental illness drug therapy
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      – SubjectFull: Psychology
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      – SubjectFull: Serotonin antagonists
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      – SubjectFull: Treatment effectiveness
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      – SubjectFull: Therapeutics
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      – TitleFull: Current perspectives on psychedelic therapy: use of serotonergic hallucinogens in clinical interventions.
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              Text: Aug2018
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