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Serum vitamin D deficiency in subjects with severe acquired brain injury and relationship with functional severity.

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Title: Serum vitamin D deficiency in subjects with severe acquired brain injury and relationship with functional severity.
Authors: Intiso, D., Fontana, A., Copetti, M., Di Rienzo, F.
Source: Brain Injury. 2018, Vol. 32 Issue 13/14, p1817-1823. 7p.
Subjects: Brain injuries, Hospital wards, Hospital admission & discharge, Inflammation, Longitudinal method, Neurology, Patients, Rehabilitation centers, Vitamin D deficiency, Cross-sectional method, Severity of illness index, Diagnosis, Functional assessment
Abstract: Background: Vitamin D may be important for the development and function of the nervous system. Low serum vitamin D levels have been detected in several neurological diseases. Objective: To ascertain the relationship between 25(OH)D serum level and disability in subjects with severe acquired brain injury (sABI). Design: Prospective cross-sectional study Methods: Consecutive subjects with sABI admitted to neuro-rehabilitation were enrolled. A sample of subjects from the neurological ward was considered the control group. Vitamin D serum levels and blood parameters were measured at admission. Disability Rating Scale (DRS), Glasgow Outcome Scale (GOS), and Level of Cognitive Functioning (LCF) were used in assessing disability. Results: A total of 104 subjects (34 F, 70 M; mean age 53.9 ± 15.2 years) were enrolled: 54 (19 F, 35 M) with sABI and 50 (15 F, 35 M) subjects as control group. Deficient mean serum levels of vitamin D (19.2 ± 9.4 ng/mL) were detected in the subjects with sABI and a significant inverse correlation between vitamin D serum levels and DRS score was detected (p = 0.04). Conclusion: Subjects with sABI showed vitamin D deficiency that might correlate to disability severity. The reason is unclear and might represent a secondary phenomenon resulting from the inflammatory process. [ABSTRACT FROM AUTHOR]
Copyright of Brain Injury is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Serum vitamin D deficiency in subjects with severe acquired brain injury and relationship with functional severity.
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  Data: <searchLink fieldCode="JN" term="%22Brain+Injury%22">Brain Injury</searchLink>. 2018, Vol. 32 Issue 13/14, p1817-1823. 7p.
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  Data: Background: Vitamin D may be important for the development and function of the nervous system. Low serum vitamin D levels have been detected in several neurological diseases. Objective: To ascertain the relationship between 25(OH)D serum level and disability in subjects with severe acquired brain injury (sABI). Design: Prospective cross-sectional study Methods: Consecutive subjects with sABI admitted to neuro-rehabilitation were enrolled. A sample of subjects from the neurological ward was considered the control group. Vitamin D serum levels and blood parameters were measured at admission. Disability Rating Scale (DRS), Glasgow Outcome Scale (GOS), and Level of Cognitive Functioning (LCF) were used in assessing disability. Results: A total of 104 subjects (34 F, 70 M; mean age 53.9 ± 15.2 years) were enrolled: 54 (19 F, 35 M) with sABI and 50 (15 F, 35 M) subjects as control group. Deficient mean serum levels of vitamin D (19.2 ± 9.4 ng/mL) were detected in the subjects with sABI and a significant inverse correlation between vitamin D serum levels and DRS score was detected (p = 0.04). Conclusion: Subjects with sABI showed vitamin D deficiency that might correlate to disability severity. The reason is unclear and might represent a secondary phenomenon resulting from the inflammatory process. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Brain Injury is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/02699052.2018.1537512
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 1817
    Subjects:
      – SubjectFull: Brain injuries
        Type: general
      – SubjectFull: Hospital wards
        Type: general
      – SubjectFull: Hospital admission & discharge
        Type: general
      – SubjectFull: Inflammation
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      – SubjectFull: Longitudinal method
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      – SubjectFull: Neurology
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      – SubjectFull: Patients
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      – SubjectFull: Rehabilitation centers
        Type: general
      – SubjectFull: Vitamin D deficiency
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Severity of illness index
        Type: general
      – SubjectFull: Diagnosis
        Type: general
      – SubjectFull: Functional assessment
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    Titles:
      – TitleFull: Serum vitamin D deficiency in subjects with severe acquired brain injury and relationship with functional severity.
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            NameFull: Intiso, D.
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            NameFull: Fontana, A.
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            NameFull: Copetti, M.
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              Text: 2018
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              Value: 32
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