View in EDS HTML Full Text PDF Full Text

Guided internet CBT versus "gold standard" depression treatments: An individual patient analysis.

Saved in:
Bibliographic Details
Title: Guided internet CBT versus "gold standard" depression treatments: An individual patient analysis.
Authors: Forand, Nicholas R., Feinberg, Jason E., Barnett, Jeffrey G., Strunk, Daniel R.
Source: Journal of Clinical Psychology. Apr2019, Vol. 75 Issue 4, p581-593. 13p. 4 Charts.
Subjects: Gold, Hamilton Depression Inventory, Behavior therapy
Abstract: Objective: Guided, computerized cognitive behavioral therapy delivered over the internet (iCBT) is a promising treatment for depression. However, comparisons to "gold standard" treatments and comparators, such as structured psychotherapy, medications, or pill placebo are rare. We compare the results of an 8‐week trial of guided iCBT to outcomes from two trials of depression treatment, Penn‐Vandy and U. Washington, using individual patient data. Method: We adjusted for sample differences by restricting the iCBT sample to randomised controlled trial (RCT) inclusion criteria and using propensity scores. Three separate samples were included in analyses: iCBT trial (N = 89), Penn‐Vandy (N = 240), and U. Washington (N = 241). Continuous outcomes were analyzed with linear‐mixed models and noninferiority analyses were conducted for iCBT versus the psychotherapy conditions. The primary outcomes were attrition, remission, and the Hamilton Rating Scale for Depression. Results: Dropout was greater in iCBT than in CT, medications, placebo (Penn‐Vandy), and CT and BA (U. Washington), but the rates of remission were similar. In continuous analyses, iCBT was superior to placebo in both RCTs and most analyses indicated no difference between iCBT and the active treatments. Conclusions: Guided iCBT appears not inferior to "gold standard" treatments for depression and is superior to placebo. Weaknesses include a lack of randomization, unblinded assessments, and a shorter "frame of treatment" in the iCBT sample. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Clinical Psychology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 135293625
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Guided internet CBT versus "gold standard" depression treatments: An individual patient analysis.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Forand%2C+Nicholas+R%2E%22">Forand, Nicholas R.</searchLink><br /><searchLink fieldCode="AR" term="%22Feinberg%2C+Jason+E%2E%22">Feinberg, Jason E.</searchLink><br /><searchLink fieldCode="AR" term="%22Barnett%2C+Jeffrey+G%2E%22">Barnett, Jeffrey G.</searchLink><br /><searchLink fieldCode="AR" term="%22Strunk%2C+Daniel+R%2E%22">Strunk, Daniel R.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Journal+of+Clinical+Psychology%22">Journal of Clinical Psychology</searchLink>. Apr2019, Vol. 75 Issue 4, p581-593. 13p. 4 Charts.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Gold%22">Gold</searchLink><br /><searchLink fieldCode="DE" term="%22Hamilton+Depression+Inventory%22">Hamilton Depression Inventory</searchLink><br /><searchLink fieldCode="DE" term="%22Behavior+therapy%22">Behavior therapy</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: Guided, computerized cognitive behavioral therapy delivered over the internet (iCBT) is a promising treatment for depression. However, comparisons to "gold standard" treatments and comparators, such as structured psychotherapy, medications, or pill placebo are rare. We compare the results of an 8‐week trial of guided iCBT to outcomes from two trials of depression treatment, Penn‐Vandy and U. Washington, using individual patient data. Method: We adjusted for sample differences by restricting the iCBT sample to randomised controlled trial (RCT) inclusion criteria and using propensity scores. Three separate samples were included in analyses: iCBT trial (N = 89), Penn‐Vandy (N = 240), and U. Washington (N = 241). Continuous outcomes were analyzed with linear‐mixed models and noninferiority analyses were conducted for iCBT versus the psychotherapy conditions. The primary outcomes were attrition, remission, and the Hamilton Rating Scale for Depression. Results: Dropout was greater in iCBT than in CT, medications, placebo (Penn‐Vandy), and CT and BA (U. Washington), but the rates of remission were similar. In continuous analyses, iCBT was superior to placebo in both RCTs and most analyses indicated no difference between iCBT and the active treatments. Conclusions: Guided iCBT appears not inferior to "gold standard" treatments for depression and is superior to placebo. Weaknesses include a lack of randomization, unblinded assessments, and a shorter "frame of treatment" in the iCBT sample. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Clinical Psychology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=135293625
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/jclp.22733
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 13
        StartPage: 581
    Subjects:
      – SubjectFull: Gold
        Type: general
      – SubjectFull: Hamilton Depression Inventory
        Type: general
      – SubjectFull: Behavior therapy
        Type: general
    Titles:
      – TitleFull: Guided internet CBT versus "gold standard" depression treatments: An individual patient analysis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Forand, Nicholas R.
      – PersonEntity:
          Name:
            NameFull: Feinberg, Jason E.
      – PersonEntity:
          Name:
            NameFull: Barnett, Jeffrey G.
      – PersonEntity:
          Name:
            NameFull: Strunk, Daniel R.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: Apr2019
              Type: published
              Y: 2019
          Identifiers:
            – Type: issn-print
              Value: 00219762
          Numbering:
            – Type: volume
              Value: 75
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Journal of Clinical Psychology
              Type: main
ResultId 1