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Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study.

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Title: Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study.
Authors: Castro, Rodolfo (AUTHOR), De Boni, Raquel B. (AUTHOR), Luz, Paula M. (AUTHOR), Velasque, Luciane (AUTHOR), Lopes, Livia V. (AUTHOR), Medina-Lara, Antonieta (AUTHOR), Cardoso, Sandra W. (AUTHOR), De Oliveira, Marilia S. (AUTHOR), Friedman, Ruth K. (AUTHOR), Grinsztejn, Beatriz (AUTHOR), Veloso, Valdiléa G. (AUTHOR)
Source: Quality of Life Research. Apr2019, Vol. 28 Issue 4, p1035-1045. 11p. 4 Charts.
Subjects: Quality of life, Sexual abstinence, Cross-sectional method, Viral load, Intimate partner violence, HIV
Geographic Terms: Brazil
Abstract: Purpose: To assess health-related quality of life (HRQoL) and its associated factors among people living with HIV/AIDS (PLWHA) in Rio de Janeiro, Brazil.Methods: A cross-sectional study including PLWHA receiving usual HIV-care at Instituto Nacional de Infectologia Evandro Chagas (INI/Fiocruz) was conducted between 2014 and 2016 in Rio de Janeiro, Brazil. The EQ-5D-3L assessed HRQoL; PHQ-2 and ASSIST were used for screening depression and substance use, respectively. Clinical variables were obtained from the INI/Fiocruz cohort database, and structured questions evaluated intimate partner violence, sexual abstinence and relationship status. Data were analysed using multivariable Tobit regression model.Results: A total of 1480 PLWHA were included: 64.7% were male at birth (38.4% men who have sex with men [MSM], 24.3% heterosexual men and 2% transgender women [TGW]); median age was 43.1 years, and 95.8% were receiving antiretroviral therapy. The median EQ-5D-3L utility score was 0.801. Results showed that the following factors: MSM and women; older age; lower educational level; no engagement in a relationship; depression screening positive; polysubstance use; and, detectable viral load were independently associated with worse HRQoL.Conclusions: PLWHA under care at INI/Fiocruz presented good HRQoL. Polysubstance use, depression and lower educational level were among the factors negatively associated with HRQoL. This was the first time that the EQ-5D-3L utility scores were calculated for a considerable number of PLWHA in Brazil, which is a fundamental piece of information for future cost-effectiveness analysis. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study.
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  Data: <searchLink fieldCode="AR" term="%22Castro%2C+Rodolfo%22">Castro, Rodolfo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22De+Boni%2C+Raquel+B%2E%22">De Boni, Raquel B.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Luz%2C+Paula+M%2E%22">Luz, Paula M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Velasque%2C+Luciane%22">Velasque, Luciane</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lopes%2C+Livia+V%2E%22">Lopes, Livia V.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Medina-Lara%2C+Antonieta%22">Medina-Lara, Antonieta</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cardoso%2C+Sandra+W%2E%22">Cardoso, Sandra W.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22De+Oliveira%2C+Marilia+S%2E%22">De Oliveira, Marilia S.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Friedman%2C+Ruth+K%2E%22">Friedman, Ruth K.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Grinsztejn%2C+Beatriz%22">Grinsztejn, Beatriz</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Veloso%2C+Valdiléa+G%2E%22">Veloso, Valdiléa G.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Quality+of+Life+Research%22">Quality of Life Research</searchLink>. Apr2019, Vol. 28 Issue 4, p1035-1045. 11p. 4 Charts.
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  Data: <bold>Purpose: </bold>To assess health-related quality of life (HRQoL) and its associated factors among people living with HIV/AIDS (PLWHA) in Rio de Janeiro, Brazil.<bold>Methods: </bold>A cross-sectional study including PLWHA receiving usual HIV-care at Instituto Nacional de Infectologia Evandro Chagas (INI/Fiocruz) was conducted between 2014 and 2016 in Rio de Janeiro, Brazil. The EQ-5D-3L assessed HRQoL; PHQ-2 and ASSIST were used for screening depression and substance use, respectively. Clinical variables were obtained from the INI/Fiocruz cohort database, and structured questions evaluated intimate partner violence, sexual abstinence and relationship status. Data were analysed using multivariable Tobit regression model.<bold>Results: </bold>A total of 1480 PLWHA were included: 64.7% were male at birth (38.4% men who have sex with men [MSM], 24.3% heterosexual men and 2% transgender women [TGW]); median age was 43.1 years, and 95.8% were receiving antiretroviral therapy. The median EQ-5D-3L utility score was 0.801. Results showed that the following factors: MSM and women; older age; lower educational level; no engagement in a relationship; depression screening positive; polysubstance use; and, detectable viral load were independently associated with worse HRQoL.<bold>Conclusions: </bold>PLWHA under care at INI/Fiocruz presented good HRQoL. Polysubstance use, depression and lower educational level were among the factors negatively associated with HRQoL. This was the first time that the EQ-5D-3L utility scores were calculated for a considerable number of PLWHA in Brazil, which is a fundamental piece of information for future cost-effectiveness analysis. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s11136-018-2044-8
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