Viral-associated haemophagocytosis with parvovirus-B19-related pancytopenia.
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| Title: | Viral-associated haemophagocytosis with parvovirus-B19-related pancytopenia. |
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| Authors: | Muir, K (AUTHOR), Todd, W T (AUTHOR), Watson, W H (AUTHOR), Fitzsimons, E (AUTHOR) |
| Source: | Lancet. 5/9/1992, Vol. 339 Issue 8802, p1139-1140. 2p. |
| Subjects: | Blood disease treatment, Blood diseases, Blood transfusion, Bone marrow examination, DNA, Immunoglobulins, Fifth disease, Congenital hemolytic anemia, Non-langerhans-cell histiocytosis, Disease complications |
| Abstract: | Viral-associated haemophagocyte syndrome in response to infection with human parvovirus B19 was seen in 2 patients with hereditary spherocytosis. Depressed reticulocyte response during acute parvovirus infection is a known cause of hypoproliferative crises in patients with reduced erythrocyte lifespan; the observation of parvovirus-associated haemophagocytosis could account for the pancytopenia that may accompany human parvovirus B19 infection. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Viral-associated haemophagocyte syndrome in response to infection with human parvovirus B19 was seen in 2 patients with hereditary spherocytosis. Depressed reticulocyte response during acute parvovirus infection is a known cause of hypoproliferative crises in patients with reduced erythrocyte lifespan; the observation of parvovirus-associated haemophagocytosis could account for the pancytopenia that may accompany human parvovirus B19 infection. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 01406736 |
| DOI: | 10.1016/0140-6736(92)90735-l |
