View in EDS

Trial of low-dose aspirin plus dipyridamole versus anticoagulants for prevention of aortocoronary vein graft occlusion.

Saved in:
Bibliographic Details
Title: Trial of low-dose aspirin plus dipyridamole versus anticoagulants for prevention of aortocoronary vein graft occlusion.
Authors: Pfisterer, M (AUTHOR), Burkart, F (AUTHOR), Jockers, G (AUTHOR), Meyer, B (AUTHOR), Regenass, S (AUTHOR), Burckhardt, D (AUTHOR), Schmitt, H E (AUTHOR), Müller-Brand, J (AUTHOR), Skarvan, K (AUTHOR), Stulz, P (AUTHOR)
Source: Lancet. 7/1/1989, Vol. 334 Issue 8653, p1-7. 7p.
Abstract: In a prospective randomised trial, 249 patients who had aortocoronary vein bypass surgery were assigned either to a platelet inhibitory drug regimen or to standard anticoagulant therapy. Treatment was replaced by placebo in half of the patients in each group after 3 months. The platelet inhibitory drug regimen--very low-dose aspirin combined with dipyridamole--was as effective as standard anticoagulant therapy to prevent early and late graft occlusion. Death, myocardial infarction, and severe bleeding occurred significantly more often in patients receiving anticoagulants, whereas mild drug-related gastrointestinal and cerebral side-effects were more common in patients taking platelet inhibitory drugs. Antithrombotic treatment should be continued for at least 1 year after coronary artery bypass graft surgery. [ABSTRACT FROM AUTHOR]
Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 136954137
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Trial of low-dose aspirin plus dipyridamole versus anticoagulants for prevention of aortocoronary vein graft occlusion.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Pfisterer%2C+M%22">Pfisterer, M</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burkart%2C+F%22">Burkart, F</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jockers%2C+G%22">Jockers, G</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Meyer%2C+B%22">Meyer, B</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Regenass%2C+S%22">Regenass, S</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burckhardt%2C+D%22">Burckhardt, D</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schmitt%2C+H+E%22">Schmitt, H E</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Müller-Brand%2C+J%22">Müller-Brand, J</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Skarvan%2C+K%22">Skarvan, K</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Stulz%2C+P%22">Stulz, P</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 7/1/1989, Vol. 334 Issue 8653, p1-7. 7p.
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: In a prospective randomised trial, 249 patients who had aortocoronary vein bypass surgery were assigned either to a platelet inhibitory drug regimen or to standard anticoagulant therapy. Treatment was replaced by placebo in half of the patients in each group after 3 months. The platelet inhibitory drug regimen--very low-dose aspirin combined with dipyridamole--was as effective as standard anticoagulant therapy to prevent early and late graft occlusion. Death, myocardial infarction, and severe bleeding occurred significantly more often in patients receiving anticoagulants, whereas mild drug-related gastrointestinal and cerebral side-effects were more common in patients taking platelet inhibitory drugs. Antithrombotic treatment should be continued for at least 1 year after coronary artery bypass graft surgery. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=136954137
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/s0140-6736(89)90253-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 1
    Titles:
      – TitleFull: Trial of low-dose aspirin plus dipyridamole versus anticoagulants for prevention of aortocoronary vein graft occlusion.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Pfisterer, M
      – PersonEntity:
          Name:
            NameFull: Burkart, F
      – PersonEntity:
          Name:
            NameFull: Jockers, G
      – PersonEntity:
          Name:
            NameFull: Meyer, B
      – PersonEntity:
          Name:
            NameFull: Regenass, S
      – PersonEntity:
          Name:
            NameFull: Burckhardt, D
      – PersonEntity:
          Name:
            NameFull: Schmitt, H E
      – PersonEntity:
          Name:
            NameFull: Müller-Brand, J
      – PersonEntity:
          Name:
            NameFull: Skarvan, K
      – PersonEntity:
          Name:
            NameFull: Stulz, P
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 7/1/1989
              Type: published
              Y: 1989
          Identifiers:
            – Type: issn-print
              Value: 01406736
          Numbering:
            – Type: volume
              Value: 334
            – Type: issue
              Value: 8653
          Titles:
            – TitleFull: Lancet
              Type: main
ResultId 1