Association of HIV status with sexual function in women aged 45–60 in England: results from two national surveys.

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Title: Association of HIV status with sexual function in women aged 45–60 in England: results from two national surveys.
Authors: Toorabally, Nasreen, Mercer, Catherine H., Mitchell, Kirstin R., Blell, Mwenza, Burns, Fiona, Gilson, Richard, McGregor-Read, Janine, Allan, Sris, De Ruiter, Annemiek, Dhairyawan, Rageshri, Fox, Julie, Gilleece, Yvonne, Jones, Rachael, Mackie, Nicola, Obeyesekera, Sharmin, Post, Frank, Reeves, Iain, Rosenvinge, Melanie, Ross, Jonathan, Sarner, Liat
Source: AIDS Care. Mar2020, Vol. 32 Issue 3, p286-295. 10p. 3 Charts.
Subjects: Diagnosis of HIV infections, Comparative studies, Confidence intervals, Health status indicators, HIV-positive persons, Questionnaires, Human sexuality, Statistics, Women, Logistic regression analysis, Data analysis software, Odds ratio
Geographic Terms: England
Abstract: Increasing numbers of women living with HIV are reaching their midlife. We explore the association of HIV status with sexual function (SF) in women aged 45–60 using two national cross-sectional surveys: the third British National Survey of Sexual Attitudes and Lifestyles ("Natsal-3") and "PRIME", a survey of women living with HIV attending HIV clinics across England. Both studies asked the same questions about SF that take account not only sexual difficulties but also the relationship context and overall level of satisfaction, which collectively allowed an overall SF score to be derived. We undertook analyses of sexually-active women aged 45–60 from Natsal-3 (N = 1228, presumed HIV-negative given the low estimated prevalence of HIV in Britain) and PRIME (N = 386 women living with HIV). Women living with HIV were compared to Natsal-3 participants using multivariable logistic regression (adjusting for key confounders identified a priori: ethnicity, ongoing relationship status, depression and number of chronic conditions) and propensity scoring. Relative to Natsal-3 participants, women living with HIV were more likely to: have low overall SF (adjusted odds ratio (AOR) 3.75 [2.15–6.56]), report ≥1 sexual problem(s) lasting ≥3 months (AOR 2.44 [1.49–4.00]), and report almost all 8 sexual problems asked about (AORs all ≥2.30). The association between HIV status and low SF remained statistically significant when using propensity scoring (AOR 2.43 [1.68–3.51]). Among women living with HIV (only), low SF was more common in those who were postmenopausal vs. Premenopausal (55.6% vs. 40.4%). This study suggests a negative association between HIV status and sexual function in women aged 45–60. We recommend routine assessment of SF in women living with HIV. [ABSTRACT FROM AUTHOR]
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  Data: Association of HIV status with sexual function in women aged 45–60 in England: results from two national surveys.
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  Data: <searchLink fieldCode="AR" term="%22Toorabally%2C+Nasreen%22">Toorabally, Nasreen</searchLink><br /><searchLink fieldCode="AR" term="%22Mercer%2C+Catherine+H%2E%22">Mercer, Catherine H.</searchLink><br /><searchLink fieldCode="AR" term="%22Mitchell%2C+Kirstin+R%2E%22">Mitchell, Kirstin R.</searchLink><br /><searchLink fieldCode="AR" term="%22Blell%2C+Mwenza%22">Blell, Mwenza</searchLink><br /><searchLink fieldCode="AR" term="%22Burns%2C+Fiona%22">Burns, Fiona</searchLink><br /><searchLink fieldCode="AR" term="%22Gilson%2C+Richard%22">Gilson, Richard</searchLink><br /><searchLink fieldCode="AR" term="%22McGregor-Read%2C+Janine%22">McGregor-Read, Janine</searchLink><br /><searchLink fieldCode="AR" term="%22Allan%2C+Sris%22">Allan, Sris</searchLink><br /><searchLink fieldCode="AR" term="%22De+Ruiter%2C+Annemiek%22">De Ruiter, Annemiek</searchLink><br /><searchLink fieldCode="AR" term="%22Dhairyawan%2C+Rageshri%22">Dhairyawan, Rageshri</searchLink><br /><searchLink fieldCode="AR" term="%22Fox%2C+Julie%22">Fox, Julie</searchLink><br /><searchLink fieldCode="AR" term="%22Gilleece%2C+Yvonne%22">Gilleece, Yvonne</searchLink><br /><searchLink fieldCode="AR" term="%22Jones%2C+Rachael%22">Jones, Rachael</searchLink><br /><searchLink fieldCode="AR" term="%22Mackie%2C+Nicola%22">Mackie, Nicola</searchLink><br /><searchLink fieldCode="AR" term="%22Obeyesekera%2C+Sharmin%22">Obeyesekera, Sharmin</searchLink><br /><searchLink fieldCode="AR" term="%22Post%2C+Frank%22">Post, Frank</searchLink><br /><searchLink fieldCode="AR" term="%22Reeves%2C+Iain%22">Reeves, Iain</searchLink><br /><searchLink fieldCode="AR" term="%22Rosenvinge%2C+Melanie%22">Rosenvinge, Melanie</searchLink><br /><searchLink fieldCode="AR" term="%22Ross%2C+Jonathan%22">Ross, Jonathan</searchLink><br /><searchLink fieldCode="AR" term="%22Sarner%2C+Liat%22">Sarner, Liat</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Mar2020, Vol. 32 Issue 3, p286-295. 10p. 3 Charts.
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  Data: <searchLink fieldCode="DE" term="%22England%22">England</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Increasing numbers of women living with HIV are reaching their midlife. We explore the association of HIV status with sexual function (SF) in women aged 45–60 using two national cross-sectional surveys: the third British National Survey of Sexual Attitudes and Lifestyles ("Natsal-3") and "PRIME", a survey of women living with HIV attending HIV clinics across England. Both studies asked the same questions about SF that take account not only sexual difficulties but also the relationship context and overall level of satisfaction, which collectively allowed an overall SF score to be derived. We undertook analyses of sexually-active women aged 45–60 from Natsal-3 (N = 1228, presumed HIV-negative given the low estimated prevalence of HIV in Britain) and PRIME (N = 386 women living with HIV). Women living with HIV were compared to Natsal-3 participants using multivariable logistic regression (adjusting for key confounders identified a priori: ethnicity, ongoing relationship status, depression and number of chronic conditions) and propensity scoring. Relative to Natsal-3 participants, women living with HIV were more likely to: have low overall SF (adjusted odds ratio (AOR) 3.75 [2.15–6.56]), report ≥1 sexual problem(s) lasting ≥3 months (AOR 2.44 [1.49–4.00]), and report almost all 8 sexual problems asked about (AORs all ≥2.30). The association between HIV status and low SF remained statistically significant when using propensity scoring (AOR 2.43 [1.68–3.51]). Among women living with HIV (only), low SF was more common in those who were postmenopausal vs. Premenopausal (55.6% vs. 40.4%). This study suggests a negative association between HIV status and sexual function in women aged 45–60. We recommend routine assessment of SF in women living with HIV. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2019.1653436
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        Text: English
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        StartPage: 286
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      – SubjectFull: Diagnosis of HIV infections
        Type: general
      – SubjectFull: Comparative studies
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Health status indicators
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      – SubjectFull: Human sexuality
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      – SubjectFull: Women
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      – SubjectFull: Logistic regression analysis
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      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Odds ratio
        Type: general
      – SubjectFull: England
        Type: general
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      – TitleFull: Association of HIV status with sexual function in women aged 45–60 in England: results from two national surveys.
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