View in EDS HTML Full Text PDF Full Text

Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS).

Saved in:
Bibliographic Details
Title: Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS).
Authors: Lincoln, Nadina B, Bradshaw, Lucy E, Constantinescu, Cris S, Day, Florence, Drummond, Avril ER, Fitzsimmons, Deborah, Harris, Shaun, Montgomery, Alan A, das Nair, Roshan, Morgan, Miriam, Scott, Julia, Evans, Susan, McKeown, Shirlee, Bharadia, Trishna, Moore, Perry, Young, Carolyn, Sharrack, Basil, Isaac, Claire, Griffths, David, Fixter, Vera
Source: Clinical Rehabilitation. Feb2020, Vol. 34 Issue 2, p229-241. 13p. 1 Diagram, 4 Charts, 2 Graphs.
Subjects: Mental health, Quality of life, Affect (Psychology), Attention, Cognition, Cognition disorders, Confidence intervals, Cost effectiveness, Employment, Fatigue (Physiology), Neuropsychological tests, Medical cooperation, Memory, Multiple sclerosis, Questionnaires, Research, Research funding, Statistical sampling, Randomized controlled trials, Quality-adjusted life years, Cognitive rehabilitation, Evaluation of human services programs, Data analysis software, Descriptive statistics
Geographic Terms: England
Abstract: Objective: To assess the clinical and cost-effectiveness of cognitive rehabilitation for attention and memory problems in people with multiple sclerosis. Design: Multicentre, pragmatic, randomized controlled trial. Setting: Community Participants: People with multiple sclerosis aged 18–69 years, who reported cognitive problems in daily life and had cognitive problems on standardized assessment. Interventions: A group cognitive rehabilitation programme delivered in 10 weekly sessions in comparison with usual care. Main measures: The primary outcome was the Multiple Sclerosis Impact Scale Psychological subscale at 12 months after randomization. Secondary outcomes included measures of everyday memory problems, mood, fatigue, cognitive abilities and employment at 6 and 12 months after randomization. Results: In all, 245 participants were allocated to cognitive rehabilitation and 204 to usual care. Mean Multiple Sclerosis Impact Scale Psychological at 12 months was 22.2 (SD = 6.1) for cognitive rehabilitation and 23.4 (SD = 6.0) for usual care group; adjusted difference −0.6, 95% confidence interval (CI) = −1.5 to 0.3, P = 0.20. No differences were observed in cognitive abilities, fatigue or employment. There were small differences in favour of cognitive rehabilitation for the Multiple Sclerosis Impact Scale Psychological at 6 months and everyday memory and mood at 6 and 12 months. There was no evidence of an effect on costs (−£808; 95% CI = −£2248 to £632) or on quality-adjusted life year gain (0.00; 95% CI = −0.01 to 0.02). Conclusion: This rehabilitation programme had no long-term benefits on the impact of multiple sclerosis on quality of life, but there was some evidence of an effect on everyday memory problems and mood. [ABSTRACT FROM AUTHOR]
Copyright of Clinical Rehabilitation is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 141487597
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS).
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Lincoln%2C+Nadina+B%22">Lincoln, Nadina B</searchLink><br /><searchLink fieldCode="AR" term="%22Bradshaw%2C+Lucy+E%22">Bradshaw, Lucy E</searchLink><br /><searchLink fieldCode="AR" term="%22Constantinescu%2C+Cris+S%22">Constantinescu, Cris S</searchLink><br /><searchLink fieldCode="AR" term="%22Day%2C+Florence%22">Day, Florence</searchLink><br /><searchLink fieldCode="AR" term="%22Drummond%2C+Avril+ER%22">Drummond, Avril ER</searchLink><br /><searchLink fieldCode="AR" term="%22Fitzsimmons%2C+Deborah%22">Fitzsimmons, Deborah</searchLink><br /><searchLink fieldCode="AR" term="%22Harris%2C+Shaun%22">Harris, Shaun</searchLink><br /><searchLink fieldCode="AR" term="%22Montgomery%2C+Alan+A%22">Montgomery, Alan A</searchLink><br /><searchLink fieldCode="AR" term="%22das+Nair%2C+Roshan%22">das Nair, Roshan</searchLink><br /><searchLink fieldCode="AR" term="%22Morgan%2C+Miriam%22">Morgan, Miriam</searchLink><br /><searchLink fieldCode="AR" term="%22Scott%2C+Julia%22">Scott, Julia</searchLink><br /><searchLink fieldCode="AR" term="%22Evans%2C+Susan%22">Evans, Susan</searchLink><br /><searchLink fieldCode="AR" term="%22McKeown%2C+Shirlee%22">McKeown, Shirlee</searchLink><br /><searchLink fieldCode="AR" term="%22Bharadia%2C+Trishna%22">Bharadia, Trishna</searchLink><br /><searchLink fieldCode="AR" term="%22Moore%2C+Perry%22">Moore, Perry</searchLink><br /><searchLink fieldCode="AR" term="%22Young%2C+Carolyn%22">Young, Carolyn</searchLink><br /><searchLink fieldCode="AR" term="%22Sharrack%2C+Basil%22">Sharrack, Basil</searchLink><br /><searchLink fieldCode="AR" term="%22Isaac%2C+Claire%22">Isaac, Claire</searchLink><br /><searchLink fieldCode="AR" term="%22Griffths%2C+David%22">Griffths, David</searchLink><br /><searchLink fieldCode="AR" term="%22Fixter%2C+Vera%22">Fixter, Vera</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Clinical+Rehabilitation%22">Clinical Rehabilitation</searchLink>. Feb2020, Vol. 34 Issue 2, p229-241. 13p. 1 Diagram, 4 Charts, 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Mental+health%22">Mental health</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Affect+%28Psychology%29%22">Affect (Psychology)</searchLink><br /><searchLink fieldCode="DE" term="%22Attention%22">Attention</searchLink><br /><searchLink fieldCode="DE" term="%22Cognition%22">Cognition</searchLink><br /><searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Cost+effectiveness%22">Cost effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Employment%22">Employment</searchLink><br /><searchLink fieldCode="DE" term="%22Fatigue+%28Physiology%29%22">Fatigue (Physiology)</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropsychological+tests%22">Neuropsychological tests</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+cooperation%22">Medical cooperation</searchLink><br /><searchLink fieldCode="DE" term="%22Memory%22">Memory</searchLink><br /><searchLink fieldCode="DE" term="%22Multiple+sclerosis%22">Multiple sclerosis</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Research%22">Research</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Statistical+sampling%22">Statistical sampling</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Quality-adjusted+life+years%22">Quality-adjusted life years</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+rehabilitation%22">Cognitive rehabilitation</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation+of+human+services+programs%22">Evaluation of human services programs</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22England%22">England</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: To assess the clinical and cost-effectiveness of cognitive rehabilitation for attention and memory problems in people with multiple sclerosis. Design: Multicentre, pragmatic, randomized controlled trial. Setting: Community Participants: People with multiple sclerosis aged 18–69 years, who reported cognitive problems in daily life and had cognitive problems on standardized assessment. Interventions: A group cognitive rehabilitation programme delivered in 10 weekly sessions in comparison with usual care. Main measures: The primary outcome was the Multiple Sclerosis Impact Scale Psychological subscale at 12 months after randomization. Secondary outcomes included measures of everyday memory problems, mood, fatigue, cognitive abilities and employment at 6 and 12 months after randomization. Results: In all, 245 participants were allocated to cognitive rehabilitation and 204 to usual care. Mean Multiple Sclerosis Impact Scale Psychological at 12 months was 22.2 (SD = 6.1) for cognitive rehabilitation and 23.4 (SD = 6.0) for usual care group; adjusted difference −0.6, 95% confidence interval (CI) = −1.5 to 0.3, P = 0.20. No differences were observed in cognitive abilities, fatigue or employment. There were small differences in favour of cognitive rehabilitation for the Multiple Sclerosis Impact Scale Psychological at 6 months and everyday memory and mood at 6 and 12 months. There was no evidence of an effect on costs (−£808; 95% CI = −£2248 to £632) or on quality-adjusted life year gain (0.00; 95% CI = −0.01 to 0.02). Conclusion: This rehabilitation programme had no long-term benefits on the impact of multiple sclerosis on quality of life, but there was some evidence of an effect on everyday memory problems and mood. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Clinical Rehabilitation is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=141487597
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1177/0269215519890378
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 13
        StartPage: 229
    Subjects:
      – SubjectFull: Mental health
        Type: general
      – SubjectFull: Quality of life
        Type: general
      – SubjectFull: Affect (Psychology)
        Type: general
      – SubjectFull: Attention
        Type: general
      – SubjectFull: Cognition
        Type: general
      – SubjectFull: Cognition disorders
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Cost effectiveness
        Type: general
      – SubjectFull: Employment
        Type: general
      – SubjectFull: Fatigue (Physiology)
        Type: general
      – SubjectFull: Neuropsychological tests
        Type: general
      – SubjectFull: Medical cooperation
        Type: general
      – SubjectFull: Memory
        Type: general
      – SubjectFull: Multiple sclerosis
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Research
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Statistical sampling
        Type: general
      – SubjectFull: Randomized controlled trials
        Type: general
      – SubjectFull: Quality-adjusted life years
        Type: general
      – SubjectFull: Cognitive rehabilitation
        Type: general
      – SubjectFull: Evaluation of human services programs
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: England
        Type: general
    Titles:
      – TitleFull: Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS).
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Lincoln, Nadina B
      – PersonEntity:
          Name:
            NameFull: Bradshaw, Lucy E
      – PersonEntity:
          Name:
            NameFull: Constantinescu, Cris S
      – PersonEntity:
          Name:
            NameFull: Day, Florence
      – PersonEntity:
          Name:
            NameFull: Drummond, Avril ER
      – PersonEntity:
          Name:
            NameFull: Fitzsimmons, Deborah
      – PersonEntity:
          Name:
            NameFull: Harris, Shaun
      – PersonEntity:
          Name:
            NameFull: Montgomery, Alan A
      – PersonEntity:
          Name:
            NameFull: das Nair, Roshan
      – PersonEntity:
          Name:
            NameFull: Morgan, Miriam
      – PersonEntity:
          Name:
            NameFull: Scott, Julia
      – PersonEntity:
          Name:
            NameFull: Evans, Susan
      – PersonEntity:
          Name:
            NameFull: McKeown, Shirlee
      – PersonEntity:
          Name:
            NameFull: Bharadia, Trishna
      – PersonEntity:
          Name:
            NameFull: Moore, Perry
      – PersonEntity:
          Name:
            NameFull: Young, Carolyn
      – PersonEntity:
          Name:
            NameFull: Sharrack, Basil
      – PersonEntity:
          Name:
            NameFull: Isaac, Claire
      – PersonEntity:
          Name:
            NameFull: Griffths, David
      – PersonEntity:
          Name:
            NameFull: Fixter, Vera
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: Feb2020
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-print
              Value: 02692155
          Numbering:
            – Type: volume
              Value: 34
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Clinical Rehabilitation
              Type: main
ResultId 1