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Nitrous Oxide Inhalant Use Disorder Preceding Symptoms Concerning for Primary Psychotic Illness.

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Title: Nitrous Oxide Inhalant Use Disorder Preceding Symptoms Concerning for Primary Psychotic Illness.
Authors: Roberts, Daniel (AUTHOR), Farahmand, Pantea (AUTHOR), Wolkin, Adam (AUTHOR)
Source: American Journal on Addictions. Nov2020, Vol. 29 Issue 6, p525-527. 3p.
Subjects: Nitrous oxide, Symptoms, Medical personnel, Diseases, Vitamin B12
Abstract: Background and Objective: Nitrous oxide has long been used recreationally for its ability to induce euphoria and other deliriant effects. In modern times, it remains a popular, legal, and widely available option for those seeking altered states. Though substance-induced psychotic symptoms have been mentioned in the literature, the potential long-term negative neuropsychiatric effects related to its use have not been well established.Methods and Results: This is a patient case report of a young man (N = 1) who initially presented with acute neurological symptoms requiring hospitalization due to heavy nitrous oxide inhalant use, and went on to present with symptoms concerning for a primary psychotic illness over multiple inpatient admissions. He provided both verbal and written consent to share his story for this case report.Discussion and Conclusions: It is important to consider nitrous oxide use as a possible contributing factor to the development of primary psychotic illness.Scientific Significance: Current literature suggests that psychosis associated with nitrous oxide use is transient and resolves upon cessation and treatment of vitamin B12 deficiency. Here, we present a patient with risk factors for psychotic illness developing psychotic illness following extensive nitrous oxide use. This report offers a unique perspective of longitudinal follow-up (often not provided with reports on this topic), and illustrates the importance of healthcare providers inquiring about nitrous oxide abuse in patients presenting with early psychotic symptoms. (Am J Addict 2020;29:525-527). [ABSTRACT FROM AUTHOR]
Copyright of American Journal on Addictions is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Label: Title
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  Data: Nitrous Oxide Inhalant Use Disorder Preceding Symptoms Concerning for Primary Psychotic Illness.
– Name: Author
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  Data: <searchLink fieldCode="AR" term="%22Roberts%2C+Daniel%22">Roberts, Daniel</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Farahmand%2C+Pantea%22">Farahmand, Pantea</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wolkin%2C+Adam%22">Wolkin, Adam</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22American+Journal+on+Addictions%22">American Journal on Addictions</searchLink>. Nov2020, Vol. 29 Issue 6, p525-527. 3p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Nitrous+oxide%22">Nitrous oxide</searchLink><br /><searchLink fieldCode="DE" term="%22Symptoms%22">Symptoms</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+personnel%22">Medical personnel</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases%22">Diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Vitamin+B12%22">Vitamin B12</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: <bold>Background and Objective: </bold>Nitrous oxide has long been used recreationally for its ability to induce euphoria and other deliriant effects. In modern times, it remains a popular, legal, and widely available option for those seeking altered states. Though substance-induced psychotic symptoms have been mentioned in the literature, the potential long-term negative neuropsychiatric effects related to its use have not been well established.<bold>Methods and Results: </bold>This is a patient case report of a young man (N = 1) who initially presented with acute neurological symptoms requiring hospitalization due to heavy nitrous oxide inhalant use, and went on to present with symptoms concerning for a primary psychotic illness over multiple inpatient admissions. He provided both verbal and written consent to share his story for this case report.<bold>Discussion and Conclusions: </bold>It is important to consider nitrous oxide use as a possible contributing factor to the development of primary psychotic illness.<bold>Scientific Significance: </bold>Current literature suggests that psychosis associated with nitrous oxide use is transient and resolves upon cessation and treatment of vitamin B12 deficiency. Here, we present a patient with risk factors for psychotic illness developing psychotic illness following extensive nitrous oxide use. This report offers a unique perspective of longitudinal follow-up (often not provided with reports on this topic), and illustrates the importance of healthcare providers inquiring about nitrous oxide abuse in patients presenting with early psychotic symptoms. (Am J Addict 2020;29:525-527). [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of American Journal on Addictions is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1111/ajad.13048
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      – Code: eng
        Text: English
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        StartPage: 525
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        Type: general
      – SubjectFull: Symptoms
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      – SubjectFull: Medical personnel
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      – SubjectFull: Diseases
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      – SubjectFull: Vitamin B12
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            – D: 01
              M: 11
              Text: Nov2020
              Type: published
              Y: 2020
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            – TitleFull: American Journal on Addictions
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