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Efficacy of the Managing Cancer and Living Meaningfully (CALM) individual psychotherapy for patients with advanced cancer: A single‐blind randomized controlled trial.

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Title: Efficacy of the Managing Cancer and Living Meaningfully (CALM) individual psychotherapy for patients with advanced cancer: A single‐blind randomized controlled trial.
Authors: Mehnert, Anja (AUTHOR), Koranyi, Susan (AUTHOR), Philipp, Rebecca (AUTHOR), Scheffold, Katharina (AUTHOR), Kriston, Levente (AUTHOR), Lehmann‐Laue, Antje (AUTHOR), Engelmann, Dorit (AUTHOR), Vehling, Sigrun (AUTHOR), Eisenecker, Christina (AUTHOR), Oechsle, Karin (AUTHOR), Schulz‐Kindermann, Frank (AUTHOR), Rodin, Gary (AUTHOR), Härter, Martin (AUTHOR)
Source: Psycho-Oncology. Nov2020, Vol. 29 Issue 11, p1895-1904. 10p. 5 Charts.
Subjects: Psychotherapy patients, Randomized controlled trials, Mental depression, Psycho-oncology, Group psychotherapy, Cancer patients, Bibliotherapy
Abstract: Objective: We aimed to determine whether the Managing Cancer and Living Meaningfully (CALM) therapy is superior to a non‐manualized supportive psycho‐oncological counselling intervention (SPI). Methods: Adult patients with advanced cancer and ≥9 points on the PHQ‐9 and/or ≥5 points on the DT were randomized to CALM or SPI. We hypothesized that CALM patients would report significantly less depression (primary outcome) on the BDI‐II and the PHQ‐9 6 months after baseline compared to SPI patients. Results: From 329 eligible patients, 206 participated (61.2% female; age: M = 57.9 [SD = 11.7]; 84.5% UICC IV stage). Of them, 99 were assigned to CALM and 107 to SPI. Intention‐to‐treat analyses revealed significantly less depressive symptoms at 6 months than at baseline (P <.001 for BDI‐II and PHQ‐9), but participants in the CALM and SPI group did not differ in depression severity (BDI‐II: P =.62, PHQ‐9: P =.998). Group differences on secondary outcomes were statistically not significant either. Conclusions: CALM therapy was associated with reduction in depressive symptoms over time but this improvement was not statistically significant different than that obtained within SPI group. [ABSTRACT FROM AUTHOR]
Copyright of Psycho-Oncology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Efficacy of the Managing Cancer and Living Meaningfully (CALM) individual psychotherapy for patients with advanced cancer: A single‐blind randomized controlled trial.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Psycho-Oncology%22&quot;&gt;Psycho-Oncology&lt;/searchLink&gt;. Nov2020, Vol. 29 Issue 11, p1895-1904. 10p. 5 Charts.
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: We aimed to determine whether the Managing Cancer and Living Meaningfully (CALM) therapy is superior to a non‐manualized supportive psycho‐oncological counselling intervention (SPI). Methods: Adult patients with advanced cancer and ≥9 points on the PHQ‐9 and/or ≥5 points on the DT were randomized to CALM or SPI. We hypothesized that CALM patients would report significantly less depression (primary outcome) on the BDI‐II and the PHQ‐9 6 months after baseline compared to SPI patients. Results: From 329 eligible patients, 206 participated (61.2% female; age: M = 57.9 [SD = 11.7]; 84.5% UICC IV stage). Of them, 99 were assigned to CALM and 107 to SPI. Intention‐to‐treat analyses revealed significantly less depressive symptoms at 6 months than at baseline (P &lt;.001 for BDI‐II and PHQ‐9), but participants in the CALM and SPI group did not differ in depression severity (BDI‐II: P =.62, PHQ‐9: P =.998). Group differences on secondary outcomes were statistically not significant either. Conclusions: CALM therapy was associated with reduction in depressive symptoms over time but this improvement was not statistically significant different than that obtained within SPI group. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of Psycho-Oncology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1002/pon.5521
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        Text: English
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      – SubjectFull: Psychotherapy patients
        Type: general
      – SubjectFull: Randomized controlled trials
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      – SubjectFull: Mental depression
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      – SubjectFull: Psycho-oncology
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      – SubjectFull: Group psychotherapy
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      – SubjectFull: Cancer patients
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      – SubjectFull: Bibliotherapy
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              Text: Nov2020
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